N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide

C140H170F6N20O11 — CID 157440087

IUPACN-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide
SMILESCC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC(C)C)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(C(F)(F)F)n3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(OC4CCC4)c3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(Oc4cncnc4)c3)CC2)cc1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(C#N)n1
InChIInChI=1S/C25H29F3N2O2.C24H27N5O2.C24H31N3O2.C24H32N2O2.C23H28N4O2.C20H23F3N4O/c1-16(29-17(2)31)18-3-5-19(6-4-18)20-9-11-30(12-10-20)24-8-7-22(13-23(24)26)32-15-21-14-25(21,27)28;1-17(28-18(2)30)19-3-5-20(6-4-19)21-8-11-29(12-9-21)22-7-10-27-24(13-22)31-23-14-25-16-26-15-23;1-17(26-18(2)28)19-6-8-20(9-7-19)21-11-14-27(15-12-21)22-10-13-25-24(16-22)29-23-4-3-5-23;1-17(2)28-24-11-9-23(10-12-24)26-15-13-22(14-16-26)21-7-5-20(6-8-21)18(3)25-19(4)27;1-4-29-23-10-9-22(21(15-24)26-23)27-13-11-20(12-14-27)19-7-5-18(6-8-19)16(2)25-17(3)28;1-13(25-14(2)28)15-3-5-16(6-4-15)17-8-11-27(12-9-17)18-7-10-24-19(26-18)20(21,22)23/h3-8,13,16,20-21H,9-12,14-15H2,1-2H3,(H,29,31);3-7,10,13-17,21H,8-9,11-12H2,1-2H3,(H,28,30);6-10,13,16-17,21,23H,3-5,11-12,14-15H2,1-2H3,(H,26,28);5-12,17-18,22H,13-16H2,1-4H3,(H,25,27);5-10,16,20H,4,11-14H2,1-3H3,(H,25,28);3-7,10,13,17H,8-9,11-12H2,1-2H3,(H,25,28)/t16-,21?;2*17-;18-;16-;13-/m000000/s1
InChIKeyBROKGFILBBZTNM-NSKCEGPGSA-N
MW2423.02 g/mol
LogP27.34
Rot. Bonds35

About N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide

N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide (PubChem CID 157440087) has the molecular formula C140H170F6N20O11 and a molecular weight of 2423.02 g/mol. Its IUPAC name is N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide.

Molecular Properties

Compound NameN-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide
PubChem CID157440087
Molecular FormulaC140H170F6N20O11
Molecular Weight2423.02 g/mol
Exact Mass2421.33
IUPAC NameN-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide
SMILESCC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC(C)C)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(C(F)(F)F)n3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(OC4CCC4)c3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(Oc4cncnc4)c3)CC2)cc1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(C#N)n1
InChIInChI=1S/C25H29F3N2O2.C24H27N5O2.C24H31N3O2.C24H32N2O2.C23H28N4O2.C20H23F3N4O/c1-16(29-17(2)31)18-3-5-19(6-4-18)20-9-11-30(12-10-20)24-8-7-22(13-23(24)26)32-15-21-14-25(21,27)28;1-17(28-18(2)30)19-3-5-20(6-4-19)21-8-11-29(12-9-21)22-7-10-27-24(13-22)31-23-14-25-16-26-15-23;1-17(26-18(2)28)19-6-8-20(9-7-19)21-11-14-27(15-12-21)22-10-13-25-24(16-22)29-23-4-3-5-23;1-17(2)28-24-11-9-23(10-12-24)26-15-13-22(14-16-26)21-7-5-20(6-8-21)18(3)25-19(4)27;1-4-29-23-10-9-22(21(15-24)26-23)27-13-11-20(12-14-27)19-7-5-18(6-8-19)16(2)25-17(3)28;1-13(25-14(2)28)15-3-5-16(6-4-15)17-8-11-27(12-9-17)18-7-10-24-19(26-18)20(21,22)23/h3-8,13,16,20-21H,9-12,14-15H2,1-2H3,(H,29,31);3-7,10,13-17,21H,8-9,11-12H2,1-2H3,(H,28,30);6-10,13,16-17,21,23H,3-5,11-12,14-15H2,1-2H3,(H,26,28);5-12,17-18,22H,13-16H2,1-4H3,(H,25,27);5-10,16,20H,4,11-14H2,1-3H3,(H,25,28);3-7,10,13,17H,8-9,11-12H2,1-2H3,(H,25,28)/t16-,21?;2*17-;18-;16-;13-/m000000/s1
InChIKeyBROKGFILBBZTNM-NSKCEGPGSA-N
XLogP27.34
TPSA354.21 Ų
H-Bond Donors6
H-Bond Acceptors25
Rotatable Bonds35
Heavy Atoms177
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002423.02
LogP ≤ 527.34
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1025

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'anil_di_alk_C(246)', 'substructure': 'N/A'}

Analyze N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide with MolForge

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Related Compounds

2-[1-[(1S)-2,2-difluorocyclopropanecarbonyl]-3,3-difluoropiperidin-4-yl]oxy-5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl]amino]pyrimidin-4-yl]benzonitrile
CID 138561050
2-[1-[(2S)-3,3-difluoro-2-hydroxypropanoyl]piperidin-4-yl]oxy-5-[2-[[5-methoxy-6-[4-(oxetan-3-yl)piperazin-1-yl]-3-pyridinyl]amino]pyrimidin-4-yl]benzonitrile
CID 138561148
2-[1-(2-Cyanoacetyl)-3,3-difluoropiperidin-4-yl]oxy-5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl]amino]pyrimidin-4-yl]benzonitrile
CID 138561161
2-[1-[(2S)-2-cyanopropanoyl]-3,3-difluoropiperidin-4-yl]oxy-5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]-2-pyridinyl]amino]pyrimidin-4-yl]benzonitrile
CID 138561187
2-[1-[(2S)-3,3-difluoro-2-hydroxypropanoyl]piperidin-4-yl]oxy-5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]-2-pyridinyl]amino]pyrimidin-4-yl]pyridine-3-carbonitrile
CID 138561226
5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]-2-pyridinyl]amino]pyrimidin-4-yl]-2-[1-[(2S)-2,3,3-trifluoropropanoyl]piperidin-4-yl]oxybenzonitrile
CID 138561312
5-[1-[(2S)-3,3-difluoro-2-hydroxypropanoyl]piperidin-4-yl]oxy-2-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]-2-pyridinyl]amino]pyrimidin-4-yl]pyridine-4-carbonitrile
CID 138561703
Tert-butyl 4-[2-cyano-6-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl]amino]pyrimidin-4-yl]pyridin-3-yl]oxy-3,3-difluoropiperidine-1-carboxylate
CID 138576503
2-[1-(2,2-Difluorocyclopropanecarbonyl)-3,3-difluoropiperidin-4-yl]oxy-5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]-2-pyridinyl]amino]pyrimidin-4-yl]benzonitrile
CID 138576588
2-[3,3-Difluoro-1-(2-fluoropropanoyl)piperidin-4-yl]oxy-5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl]amino]pyrimidin-4-yl]benzonitrile
CID 138576589
2-[1-(2-Cyanopropanoyl)-3,3-difluoropiperidin-4-yl]oxy-5-[2-[[6-methoxy-5-[4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl]amino]pyrimidin-4-yl]benzonitrile
CID 138576666
2-[3,3-difluoro-1-[(2S)-2-hydroxypropanoyl]piperidin-4-yl]oxy-5-[2-[[5-methoxy-6-[4-(oxetan-3-yl)piperazin-1-yl]pyridin-3-yl]amino]pyrimidin-4-yl]benzonitrile
CID 138576713

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
The IUPAC name of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide (CID 157440087) is N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide.
What is the SMILES notation for N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
The canonical SMILES for N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide is CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC(C)C)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(C(F)(F)F)n3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(OC4CCC4)c3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(Oc4cncnc4)c3)CC2)cc1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(C#N)n1.
What is the InChIKey of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
The InChIKey is BROKGFILBBZTNM-NSKCEGPGSA-N. The full InChI is InChI=1S/C25H29F3N2O2.C24H27N5O2.C24H31N3O2.C24H32N2O2.C23H28N4O2.C20H23F3N4O/c1-16(29-17(2)31)18-3-5-19(6-4-18)20-9-11-30(12-10-20)24-8-7-22(13-23(24)26)32-15-21-14-25(21,27)28;1-17(28-18(2)30)19-3-5-20(6-4-19)21-8-11-29(12-9-21)22-7-10-27-24(13-22)31-23-14-25-16-26-15-23;1-17(26-18(2)28)19-6-8-20(9-7-19)21-11-14-27(15-12-21)22-10-13-25-24(16-22)29-23-4-3-5-23;1-17(2)28-24-11-9-23(10-12-24)26-15-13-22(14-16-26)21-7-5-20(6-8-21)18(3)25-19(4)27;1-4-29-23-10-9-22(21(15-24)26-23)27-13-11-20(12-14-27)19-7-5-18(6-8-19)16(2)25-17(3)28;1-13(25-14(2)28)15-3-5-16(6-4-15)17-8-11-27(12-9-17)18-7-10-24-19(26-18)20(21,22)23/h3-8,13,16,20-21H,9-12,14-15H2,1-2H3,(H,29,31);3-7,10,13-17,21H,8-9,11-12H2,1-2H3,(H,28,30);6-10,13,16-17,21,23H,3-5,11-12,14-15H2,1-2H3,(H,26,28);5-12,17-18,22H,13-16H2,1-4H3,(H,25,27);5-10,16,20H,4,11-14H2,1-3H3,(H,25,28);3-7,10,13,17H,8-9,11-12H2,1-2H3,(H,25,28)/t16-,21?;2*17-;18-;16-;13-/m000000/s1.
What are the key properties of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide has a molecular weight of 2423.02 g/mol, XLogP of 27.34, 35 rotatable bonds, 6 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-cyclobutyloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide is sourced from PubChem (CID 157440087), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).