3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide

C89H70N32O7S — CID 157441785

About 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide

3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide (PubChem CID 157441785) has the molecular formula C89H70N32O7S and a molecular weight of 1731.82 g/mol. Its IUPAC name is 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide.

Molecular Properties

• Compound Name: 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide
• PubChem CID: 157441785
• Molecular Formula: C89H70N32O7S
• Molecular Weight: 1731.82 g/mol
• Exact Mass: 1730.58
• IUPAC Name: 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide
• SMILES: CS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3n[nH]c4ccccc34)n2)cc1.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1ccc2[nH]ccc2c1.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1ccc2cc[nH]c2c1.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1cccc2cc[nH]c12.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1cccn2ncnc12
• InChI: InChI=1S/C19H16N6O3S.3C18H14N6O.C16H12N8O/c1-29(27,28)12-8-6-11(7-9-12)15-10-21-17(20)16(22-15)19(26)23-18-13-4-2-3-5-14(13)24-25-18;19-17-16(23-14(10-22-17)12-4-2-7-20-9-12)18(25)24-13-5-1-3-11-6-8-21-15(11)13;19-17-16(24-15(10-22-17)12-2-1-6-20-9-12)18(25)23-13-3-4-14-11(8-13)5-7-21-14;19-17-16(24-15(10-22-17)12-2-1-6-20-9-12)18(25)23-13-4-3-11-5-7-21-14(11)8-13;17-14-13(22-12(8-19-14)10-3-1-5-18-7-10)16(25)23-11-4-2-6-24-15(11)20-9-21-24/h2-10H,1H3,(H2,20,21)(H2,23,24,25,26);1-10,21H,(H2,19,22)(H,24,25);2*1-10,21H,(H2,19,22)(H,23,25);1-9H,(H2,17,19)(H,23,25)
• InChIKey: BRTJHZVJPSDQPJ-UHFFFAOYSA-N
• XLogP: 12.24
• TPSA: 596.44 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 30
• Rotatable Bonds: 16
• Heavy Atoms: 129
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1731.82
LogP ≤ 5	12.24
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide?

The IUPAC name of 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide (CID 157441785) is 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide.

What is the SMILES notation for 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide?

The canonical SMILES for 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide is CS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3n[nH]c4ccccc34)n2)cc1.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1ccc2[nH]ccc2c1.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1ccc2cc[nH]c2c1.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1cccc2cc[nH]c12.Nc1ncc(-c2cccnc2)nc1C(=O)Nc1cccn2ncnc12.

What is the InChIKey of 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide?

The InChIKey is BRTJHZVJPSDQPJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H16N6O3S.3C18H14N6O.C16H12N8O/c1-29(27,28)12-8-6-11(7-9-12)15-10-21-17(20)16(22-15)19(26)23-18-13-4-2-3-5-14(13)24-25-18;19-17-16(23-14(10-22-17)12-4-2-7-20-9-12)18(25)24-13-5-1-3-11-6-8-21-15(11)13;19-17-16(24-15(10-22-17)12-2-1-6-20-9-12)18(25)23-13-3-4-14-11(8-13)5-7-21-14;19-17-16(24-15(10-22-17)12-2-1-6-20-9-12)18(25)23-13-4-3-11-5-7-21-14(11)8-13;17-14-13(22-12(8-19-14)10-3-1-5-18-7-10)16(25)23-11-4-2-6-24-15(11)20-9-21-24/h2-10H,1H3,(H2,20,21)(H2,23,24,25,26);1-10,21H,(H2,19,22)(H,24,25);2*1-10,21H,(H2,19,22)(H,23,25);1-9H,(H2,17,19)(H,23,25).

What are the key properties of 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide?

3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide has a molecular weight of 1731.82 g/mol, XLogP of 12.24, 16 rotatable bonds, 14 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-(1H-indazol-3-yl)-6-(4-methylsulfonylphenyl)pyrazine-2-carboxamide;3-amino-N-(1H-indol-5-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-6-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-N-(1H-indol-7-yl)-6-pyridin-3-ylpyrazine-2-carboxamide;3-amino-6-pyridin-3-yl-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pyrazine-2-carboxamide is sourced from PubChem (CID 157441785), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).