N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide

C116H94F8N30O5 — CID 157446013

IUPACN-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide
SMILESCc1cc(-c2ncc(CNC(=O)c3ccc(-c4cnccn4)cn3)cc2F)ccn1.Cc1cc(-c2ncc(CNC(=O)c3ccc(-c4cnccn4)nc3)cc2F)ccn1.Cc1cc(CNC(=O)c2ccc(-c3cccnn3)nc2)cnc1-c1ccnc(C(C)(F)F)c1.Cc1cc(CNC(=O)c2ccc(-c3cnccn3)cn2)cnc1-c1ccnc(C(C)(F)F)c1.Cc1cc(CNC(=O)c2ccc(-c3cnccn3)nc2)cnc1-c1ccnc(C(C)(F)F)c1
InChIInChI=1S/3C24H20F2N6O.2C22H17FN6O/c1-15-9-16(11-31-22(15)17-5-6-29-21(10-17)24(2,25)26)12-32-23(33)18-3-4-19(30-13-18)20-14-27-7-8-28-20;1-15-9-16(11-31-22(15)17-5-6-29-21(10-17)24(2,25)26)12-32-23(33)19-4-3-18(13-30-19)20-14-27-7-8-28-20;1-15-10-16(12-29-22(15)17-7-9-27-21(11-17)24(2,25)26)13-30-23(33)18-5-6-19(28-14-18)20-4-3-8-31-32-20;1-14-8-16(4-5-25-14)21-18(23)9-15(10-28-21)11-29-22(30)17-2-3-19(27-12-17)20-13-24-6-7-26-20;1-14-8-16(4-5-25-14)21-18(23)9-15(10-28-21)11-29-22(30)19-3-2-17(12-27-19)20-13-24-6-7-26-20/h2*3-11,13-14H,12H2,1-2H3,(H,32,33);3-12,14H,13H2,1-2H3,(H,30,33);2*2-10,12-13H,11H2,1H3,(H,29,30)
InChIKeyBSFPFOZUWOLEPD-UHFFFAOYSA-N
MW2140.22 g/mol
LogP19.78
Rot. Bonds28

About N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide

N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide (PubChem CID 157446013) has the molecular formula C116H94F8N30O5 and a molecular weight of 2140.22 g/mol. Its IUPAC name is N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide.

Molecular Properties

Compound NameN-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide
PubChem CID157446013
Molecular FormulaC116H94F8N30O5
Molecular Weight2140.22 g/mol
Exact Mass2138.79
IUPAC NameN-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide
SMILESCc1cc(-c2ncc(CNC(=O)c3ccc(-c4cnccn4)cn3)cc2F)ccn1.Cc1cc(-c2ncc(CNC(=O)c3ccc(-c4cnccn4)nc3)cc2F)ccn1.Cc1cc(CNC(=O)c2ccc(-c3cccnn3)nc2)cnc1-c1ccnc(C(C)(F)F)c1.Cc1cc(CNC(=O)c2ccc(-c3cnccn3)cn2)cnc1-c1ccnc(C(C)(F)F)c1.Cc1cc(CNC(=O)c2ccc(-c3cnccn3)nc2)cnc1-c1ccnc(C(C)(F)F)c1
InChIInChI=1S/3C24H20F2N6O.2C22H17FN6O/c1-15-9-16(11-31-22(15)17-5-6-29-21(10-17)24(2,25)26)12-32-23(33)18-3-4-19(30-13-18)20-14-27-7-8-28-20;1-15-9-16(11-31-22(15)17-5-6-29-21(10-17)24(2,25)26)12-32-23(33)19-4-3-18(13-30-19)20-14-27-7-8-28-20;1-15-10-16(12-29-22(15)17-7-9-27-21(11-17)24(2,25)26)13-30-23(33)18-5-6-19(28-14-18)20-4-3-8-31-32-20;1-14-8-16(4-5-25-14)21-18(23)9-15(10-28-21)11-29-22(30)17-2-3-19(27-12-17)20-13-24-6-7-26-20;1-14-8-16(4-5-25-14)21-18(23)9-15(10-28-21)11-29-22(30)19-3-2-17(12-27-19)20-13-24-6-7-26-20/h2*3-11,13-14H,12H2,1-2H3,(H,32,33);3-12,14H,13H2,1-2H3,(H,30,33);2*2-10,12-13H,11H2,1H3,(H,29,30)
InChIKeyBSFPFOZUWOLEPD-UHFFFAOYSA-N
XLogP19.78
TPSA467.75 Ų
H-Bond Donors5
H-Bond Acceptors30
Rotatable Bonds28
Heavy Atoms159
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002140.22
LogP ≤ 519.78
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1030

Analyze N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

3-amino-N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(triazol-1-yl)piperidin-1-yl]-3-pyridinyl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide
CID 91937645
3-amino-N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(triazol-1-yl)piperidin-1-yl]-3-pyridinyl]-6-[2-fluoro-5-(propan-2-ylcarbamoyl)phenyl]pyridine-2-carboxamide
CID 91937648
N-(cis-3-fluoro-1-(pyridin-4-ylmethyl)piperidin-4-yl)-5-(4-(4-fluorobenzyl)piperazine-1-carbonyl)picolinamide
CID 66710307
[4-Fluoro-4-[[6-(trifluoromethyl)pyridazin-3-yl]methyl]piperidin-1-yl]-(2-pyridin-4-yl-3-pyridinyl)methanone
CID 163385912
US12319655, Example 444
CID 168930010
US12319655, Example 374
CID 168930391
US12319655, Example 42
CID 168930653
US12319655, Example 463
CID 169024585
US12319655, Example 495
CID 169024738
US12319655, Example 492
CID 169024740
US12319655, Example 477
CID 169024741
US12319655, Example 330
CID 170100795

Frequently Asked Questions

What is the IUPAC name of N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide?
The IUPAC name of N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide (CID 157446013) is N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide.
What is the SMILES notation for N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide?
The canonical SMILES for N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide is Cc1cc(-c2ncc(CNC(=O)c3ccc(-c4cnccn4)cn3)cc2F)ccn1.Cc1cc(-c2ncc(CNC(=O)c3ccc(-c4cnccn4)nc3)cc2F)ccn1.Cc1cc(CNC(=O)c2ccc(-c3cccnn3)nc2)cnc1-c1ccnc(C(C)(F)F)c1.Cc1cc(CNC(=O)c2ccc(-c3cnccn3)cn2)cnc1-c1ccnc(C(C)(F)F)c1.Cc1cc(CNC(=O)c2ccc(-c3cnccn3)nc2)cnc1-c1ccnc(C(C)(F)F)c1.
What is the InChIKey of N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide?
The InChIKey is BSFPFOZUWOLEPD-UHFFFAOYSA-N. The full InChI is InChI=1S/3C24H20F2N6O.2C22H17FN6O/c1-15-9-16(11-31-22(15)17-5-6-29-21(10-17)24(2,25)26)12-32-23(33)18-3-4-19(30-13-18)20-14-27-7-8-28-20;1-15-9-16(11-31-22(15)17-5-6-29-21(10-17)24(2,25)26)12-32-23(33)19-4-3-18(13-30-19)20-14-27-7-8-28-20;1-15-10-16(12-29-22(15)17-7-9-27-21(11-17)24(2,25)26)13-30-23(33)18-5-6-19(28-14-18)20-4-3-8-31-32-20;1-14-8-16(4-5-25-14)21-18(23)9-15(10-28-21)11-29-22(30)17-2-3-19(27-12-17)20-13-24-6-7-26-20;1-14-8-16(4-5-25-14)21-18(23)9-15(10-28-21)11-29-22(30)19-3-2-17(12-27-19)20-13-24-6-7-26-20/h2*3-11,13-14H,12H2,1-2H3,(H,32,33);3-12,14H,13H2,1-2H3,(H,30,33);2*2-10,12-13H,11H2,1H3,(H,29,30).
What are the key properties of N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide?
N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide has a molecular weight of 2140.22 g/mol, XLogP of 19.78, 28 rotatable bonds, 5 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide;N-[[6-[2-(1,1-difluoroethyl)-4-pyridinyl]-5-methyl-3-pyridinyl]methyl]-6-pyridazin-3-ylpyridine-3-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-5-pyrazin-2-ylpyridine-2-carboxamide;N-[[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]-6-pyrazin-2-ylpyridine-3-carboxamide is sourced from PubChem (CID 157446013), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).