2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide

C92H111N25O4 — CID 157446104

IUPAC2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide
SMILESCC(C)c1ccc(NC(=O)C2CCCNC2)c(N2CCN(c3cnccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2ccccn2)c(N2CCN(c3cnccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2cccnc2)c(N2CCN(c3ncccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2cccnc2N)c(N2CCN(c3cnccn3)CC2)c1
InChIInChI=1S/C23H27N7O.C23H26N6O.C23H32N6O.C23H26N6O/c1-16(2)17-5-6-19(28-23(31)18-4-3-7-27-22(18)24)20(14-17)29-10-12-30(13-11-29)21-15-25-8-9-26-21;1-17(2)18-6-7-20(27-22(30)19-5-3-8-24-16-19)21(15-18)28-11-13-29(14-12-28)23-25-9-4-10-26-23;1-17(2)18-5-6-20(27-23(30)19-4-3-7-24-15-19)21(14-18)28-10-12-29(13-11-28)22-16-25-8-9-26-22;1-17(2)18-6-7-19(27-23(30)20-5-3-4-8-25-20)21(15-18)28-11-13-29(14-12-28)22-16-24-9-10-26-22/h3-9,14-16H,10-13H2,1-2H3,(H2,24,27)(H,28,31);3-10,15-17H,11-14H2,1-2H3,(H,27,30);5-6,8-9,14,16-17,19,24H,3-4,7,10-13,15H2,1-2H3,(H,27,30);3-10,15-17H,11-14H2,1-2H3,(H,27,30)
InChIKeyBSFVULNKHFRMCZ-UHFFFAOYSA-N
MW1631.07 g/mol
LogP13.17
Rot. Bonds20

About 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide

2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide (PubChem CID 157446104) has the molecular formula C92H111N25O4 and a molecular weight of 1631.07 g/mol. Its IUPAC name is 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide.

Molecular Properties

Compound Name2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide
PubChem CID157446104
Molecular FormulaC92H111N25O4
Molecular Weight1631.07 g/mol
Exact Mass1629.93
IUPAC Name2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide
SMILESCC(C)c1ccc(NC(=O)C2CCCNC2)c(N2CCN(c3cnccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2ccccn2)c(N2CCN(c3cnccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2cccnc2)c(N2CCN(c3ncccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2cccnc2N)c(N2CCN(c3cnccn3)CC2)c1
InChIInChI=1S/C23H27N7O.C23H26N6O.C23H32N6O.C23H26N6O/c1-16(2)17-5-6-19(28-23(31)18-4-3-7-27-22(18)24)20(14-17)29-10-12-30(13-11-29)21-15-25-8-9-26-21;1-17(2)18-6-7-20(27-22(30)19-5-3-8-24-16-19)21(15-18)28-11-13-29(14-12-28)23-25-9-4-10-26-23;1-17(2)18-5-6-20(27-23(30)19-4-3-7-24-15-19)21(14-18)28-10-12-29(13-11-28)22-16-25-8-9-26-22;1-17(2)18-6-7-19(27-23(30)20-5-3-4-8-25-20)21(15-18)28-11-13-29(14-12-28)22-16-24-9-10-26-22/h3-9,14-16H,10-13H2,1-2H3,(H2,24,27)(H,28,31);3-10,15-17H,11-14H2,1-2H3,(H,27,30);5-6,8-9,14,16-17,19,24H,3-4,7,10-13,15H2,1-2H3,(H,27,30);3-10,15-17H,11-14H2,1-2H3,(H,27,30)
InChIKeyBSFVULNKHFRMCZ-UHFFFAOYSA-N
XLogP13.17
TPSA322.16 Ų
H-Bond Donors6
H-Bond Acceptors25
Rotatable Bonds20
Heavy Atoms121
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001631.07
LogP ≤ 513.17
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1025

Analyze 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide with MolForge

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Related Compounds

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N-[4-isopropyl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]-2-methyl-pyridine-3-carboxamide
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N-[4-isopropyl-2-[4-(6-methylpyrazin-2-yl)piperazin-1-yl]phenyl]pyridine-3-carboxamide
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N-[4-isopropyl-2-(4-pyrimidin-4-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide
CID 53311639
N-[4-isopropyl-2-[4-(2-methylpyrimidin-4-yl)piperazin-1-yl]phenyl]pyridine-3-carboxamide
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2-amino-N-[4-isopropyl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide
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Frequently Asked Questions

What is the IUPAC name of 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide?
The IUPAC name of 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide (CID 157446104) is 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide.
What is the SMILES notation for 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide?
The canonical SMILES for 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide is CC(C)c1ccc(NC(=O)C2CCCNC2)c(N2CCN(c3cnccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2ccccn2)c(N2CCN(c3cnccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2cccnc2)c(N2CCN(c3ncccn3)CC2)c1.CC(C)c1ccc(NC(=O)c2cccnc2N)c(N2CCN(c3cnccn3)CC2)c1.
What is the InChIKey of 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide?
The InChIKey is BSFVULNKHFRMCZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H27N7O.C23H26N6O.C23H32N6O.C23H26N6O/c1-16(2)17-5-6-19(28-23(31)18-4-3-7-27-22(18)24)20(14-17)29-10-12-30(13-11-29)21-15-25-8-9-26-21;1-17(2)18-6-7-20(27-22(30)19-5-3-8-24-16-19)21(15-18)28-11-13-29(14-12-28)23-25-9-4-10-26-23;1-17(2)18-5-6-20(27-23(30)19-4-3-7-24-15-19)21(14-18)28-10-12-29(13-11-28)22-16-25-8-9-26-22;1-17(2)18-6-7-19(27-23(30)20-5-3-4-8-25-20)21(15-18)28-11-13-29(14-12-28)22-16-24-9-10-26-22/h3-9,14-16H,10-13H2,1-2H3,(H2,24,27)(H,28,31);3-10,15-17H,11-14H2,1-2H3,(H,27,30);5-6,8-9,14,16-17,19,24H,3-4,7,10-13,15H2,1-2H3,(H,27,30);3-10,15-17H,11-14H2,1-2H3,(H,27,30).
What are the key properties of 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide?
2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide has a molecular weight of 1631.07 g/mol, XLogP of 13.17, 20 rotatable bonds, 6 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]piperidine-3-carboxamide;N-[4-propan-2-yl-2-(4-pyrazin-2-ylpiperazin-1-yl)phenyl]pyridine-2-carboxamide;N-[4-propan-2-yl-2-(4-pyrimidin-2-ylpiperazin-1-yl)phenyl]pyridine-3-carboxamide is sourced from PubChem (CID 157446104), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).