6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide

C103H66Cl4F6N20O3 — CID 157457218

About 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide

6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide (PubChem CID 157457218) has the molecular formula C103H66Cl4F6N20O3 and a molecular weight of 1887.60 g/mol. Its IUPAC name is 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide.

Molecular Properties

• Compound Name: 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide
• PubChem CID: 157457218
• Molecular Formula: C103H66Cl4F6N20O3
• Molecular Weight: 1887.60 g/mol
• Exact Mass: 1884.43
• IUPAC Name: 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide
• SMILES: COc1ccnc2ccc(-c3cccnc3-c3cc(Cl)c(F)cc3F)cc12.Cc1cc(-c2ncccc2-c2ccc3nccc(C(N)=O)c3c2)ccc1F.Fc1ccc(-c2ncccc2-c2ccc3ncc(-c4ncc[nH]4)n3c2)cc1Cl.Fc1ccc(-c2ncccc2-c2ccc3ncc(-c4ncn[nH]4)n3c2)cc1Cl.NC(=O)c1cnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cn12
• InChI: InChI=1S/C22H16FN3O.C21H13ClF2N2O.C21H13ClFN5.C20H12ClFN6.C19H12ClFN4O/c1-13-11-15(4-6-19(13)23)21-16(3-2-9-26-21)14-5-7-20-18(12-14)17(22(24)27)8-10-25-20;1-27-20-6-8-25-19-5-4-12(9-15(19)20)13-3-2-7-26-21(13)14-10-16(22)18(24)11-17(14)23;22-16-10-13(3-5-17(16)23)20-15(2-1-7-24-20)14-4-6-19-27-11-18(28(19)12-14)21-25-8-9-26-21;21-15-8-12(3-5-16(15)22)19-14(2-1-7-23-19)13-4-6-18-24-9-17(28(18)10-13)20-25-11-26-27-20;20-14-8-11(3-5-15(14)21)18-13(2-1-7-23-18)12-4-6-17-24-9-16(19(22)26)25(17)10-12/h2-12H,1H3,(H2,24,27);2-11H,1H3;1-12H,(H,25,26);1-11H,(H,25,26,27);1-10H,(H2,22,26)
• InChIKey: BTMSONOHJJCGLK-UHFFFAOYSA-N
• XLogP: 24.26
• TPSA: 307.79 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 19
• Rotatable Bonds: 15
• Heavy Atoms: 136
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1887.60
LogP ≤ 5	24.26
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	19

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'halogenated_ring_1', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide?

The IUPAC name of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide (CID 157457218) is 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide.

What is the SMILES notation for 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide?

The canonical SMILES for 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide is COc1ccnc2ccc(-c3cccnc3-c3cc(Cl)c(F)cc3F)cc12.Cc1cc(-c2ncccc2-c2ccc3nccc(C(N)=O)c3c2)ccc1F.Fc1ccc(-c2ncccc2-c2ccc3ncc(-c4ncc[nH]4)n3c2)cc1Cl.Fc1ccc(-c2ncccc2-c2ccc3ncc(-c4ncn[nH]4)n3c2)cc1Cl.NC(=O)c1cnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cn12.

What is the InChIKey of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide?

The InChIKey is BTMSONOHJJCGLK-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H16FN3O.C21H13ClF2N2O.C21H13ClFN5.C20H12ClFN6.C19H12ClFN4O/c1-13-11-15(4-6-19(13)23)21-16(3-2-9-26-21)14-5-7-20-18(12-14)17(22(24)27)8-10-25-20;1-27-20-6-8-25-19-5-4-12(9-15(19)20)13-3-2-7-26-21(13)14-10-16(22)18(24)11-17(14)23;22-16-10-13(3-5-17(16)23)20-15(2-1-7-24-20)14-4-6-19-27-11-18(28(19)12-14)21-25-8-9-26-21;21-15-8-12(3-5-16(15)22)19-14(2-1-7-23-19)13-4-6-18-24-9-17(28(18)10-13)20-25-11-26-27-20;20-14-8-11(3-5-15(14)21)18-13(2-1-7-23-18)12-4-6-17-24-9-16(19(22)26)25(17)10-12/h2-12H,1H3,(H2,24,27);2-11H,1H3;1-12H,(H,25,26);1-11H,(H,25,26,27);1-10H,(H2,22,26).

What are the key properties of 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide?

6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide has a molecular weight of 1887.60 g/mol, XLogP of 24.26, 15 rotatable bonds, 4 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[2-(5-chloro-2,4-difluorophenyl)-3-pyridinyl]-4-methoxyquinoline;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxamide;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-imidazol-2-yl)imidazo[1,2-a]pyridine;6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-3-(1H-1,2,4-triazol-5-yl)imidazo[1,2-a]pyridine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinoline-4-carboxamide is sourced from PubChem (CID 157457218), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).