[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone

C125H128Cl5F7N18O6 — CID 157457941

About [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone

[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone (PubChem CID 157457941) has the molecular formula C125H128Cl5F7N18O6 and a molecular weight of 2288.77 g/mol. Its IUPAC name is [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone.

Molecular Properties

• Compound Name: [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone
• PubChem CID: 157457941
• Molecular Formula: C125H128Cl5F7N18O6
• Molecular Weight: 2288.77 g/mol
• Exact Mass: 2284.86
• IUPAC Name: [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone
• SMILES: CC(F)(F)c1ccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.CC(F)(F)c1ccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1F.CC(F)(F)c1ccc(CN2CCC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.Cc1ccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.O=C(c1ccc(-c2ncn[nH]2)cc1)N1CC2(CCN(C(=O)c3cc4cc(Cl)ccc4[nH]3)CC2)C1
• InChI: InChI=1S/C26H28ClF2N3O.C25H25ClF3N3O.C25H26ClF2N3O.C25H23ClN6O2.C24H26ClN3O/c1-25(28,29)20-4-2-18(3-5-20)16-31-11-8-26(17-31)9-12-32(13-10-26)24(33)23-15-19-14-21(27)6-7-22(19)30-23;1-24(28,29)19-4-2-16(10-20(19)27)13-31-14-25(15-31)6-8-32(9-7-25)23(33)22-12-17-11-18(26)3-5-21(17)30-22;1-24(27,28)19-4-2-17(3-5-19)14-30-15-25(16-30)8-10-31(11-9-25)23(32)22-13-18-12-20(26)6-7-21(18)29-22;26-19-5-6-20-18(11-19)12-21(29-20)24(34)31-9-7-25(8-10-31)13-32(14-25)23(33)17-3-1-16(2-4-17)22-27-15-28-30-22;1-17-2-4-18(5-3-17)14-27-15-24(16-27)8-10-28(11-9-24)23(29)22-13-19-12-20(25)6-7-21(19)26-22/h2-7,14-15,30H,8-13,16-17H2,1H3;2-5,10-12,30H,6-9,13-15H2,1H3;2-7,12-13,29H,8-11,14-16H2,1H3;1-6,11-12,15,29H,7-10,13-14H2,(H,27,28,30);2-7,12-13,26H,8-11,14-16H2,1H3
• InChIKey: BTOTWBGIDBZSHL-UHFFFAOYSA-N
• XLogP: 26.40
• TPSA: 255.34 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 12
• Rotatable Bonds: 18
• Heavy Atoms: 161
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2288.77
LogP ≤ 5	26.40
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	12

Frequently Asked Questions

What is the IUPAC name of [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

The IUPAC name of [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone (CID 157457941) is [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone.

What is the SMILES notation for [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

The canonical SMILES for [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone is CC(F)(F)c1ccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.CC(F)(F)c1ccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1F.CC(F)(F)c1ccc(CN2CCC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.Cc1ccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.O=C(c1ccc(-c2ncn[nH]2)cc1)N1CC2(CCN(C(=O)c3cc4cc(Cl)ccc4[nH]3)CC2)C1.

What is the InChIKey of [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

The InChIKey is BTOTWBGIDBZSHL-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H28ClF2N3O.C25H25ClF3N3O.C25H26ClF2N3O.C25H23ClN6O2.C24H26ClN3O/c1-25(28,29)20-4-2-18(3-5-20)16-31-11-8-26(17-31)9-12-32(13-10-26)24(33)23-15-19-14-21(27)6-7-22(19)30-23;1-24(28,29)19-4-2-16(10-20(19)27)13-31-14-25(15-31)6-8-32(9-7-25)23(33)22-12-17-11-18(26)3-5-21(17)30-22;1-24(27,28)19-4-2-17(3-5-19)14-30-15-25(16-30)8-10-31(11-9-25)23(32)22-13-18-12-20(26)6-7-21(18)29-22;26-19-5-6-20-18(11-19)12-21(29-20)24(34)31-9-7-25(8-10-31)13-32(14-25)23(33)17-3-1-16(2-4-17)22-27-15-28-30-22;1-17-2-4-18(5-3-17)14-27-15-24(16-27)8-10-28(11-9-24)23(29)22-13-19-12-20(25)6-7-21(19)26-22/h2-7,14-15,30H,8-13,16-17H2,1H3;2-5,10-12,30H,6-9,13-15H2,1H3;2-7,12-13,29H,8-11,14-16H2,1H3;1-6,11-12,15,29H,7-10,13-14H2,(H,27,28,30);2-7,12-13,26H,8-11,14-16H2,1H3.

What are the key properties of [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone has a molecular weight of 2288.77 g/mol, XLogP of 26.40, 18 rotatable bonds, 6 hydrogen bond donors, and 12 hydrogen bond acceptors.

Where does this data come from?

All data for [7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1H-1,2,4-triazol-5-yl)phenyl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)-3-fluorophenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[[4-(1,1-difluoroethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(5-chloro-1H-indol-2-yl)-[2-[(4-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone is sourced from PubChem (CID 157457941), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).