2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide

C78H87Cl2N21O15S — CID 157458987

IUPAC2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide
SMILESCc1ccc2[nH]cc(CC(=O)N3CCn4nc(C(=O)NO)cc4C3)c2c1.Cc1nc(CC(=O)N2CCn3nc(C(=O)NO)cc3C2)cs1.Cn1c(C(=O)N2CCn3cc(C(=O)NO)cc3C2)cc(Cl)c1Cl.Cn1ccc2cc(C(=O)N3CCn4cc(C(=O)NO)cc4C3)ccc21.O=C(NO)c1cc2n(c1)CCN(C(=O)C1CCCCC1)C2
InChIInChI=1S/C18H19N5O3.C18H18N4O3.C15H21N3O3.C14H14Cl2N4O3.C13H15N5O3S/c1-11-2-3-15-14(6-11)12(9-19-15)7-17(24)22-4-5-23-13(10-22)8-16(20-23)18(25)21-26;1-20-5-4-12-8-13(2-3-16(12)20)18(24)22-7-6-21-10-14(17(23)19-25)9-15(21)11-22;19-14(16-21)12-8-13-10-18(7-6-17(13)9-12)15(20)11-4-2-1-3-5-11;1-18-11(5-10(15)12(18)16)14(22)20-3-2-19-6-8(13(21)17-23)4-9(19)7-20;1-8-14-9(7-22-8)4-12(19)17-2-3-18-10(6-17)5-11(15-18)13(20)16-21/h2-3,6,8-9,19,26H,4-5,7,10H2,1H3,(H,21,25);2-5,8-10,25H,6-7,11H2,1H3,(H,19,23);8-9,11,21H,1-7,10H2,(H,16,19);4-6,23H,2-3,7H2,1H3,(H,17,21);5,7,21H,2-4,6H2,1H3,(H,16,20)
InChIKeyBTRVJGXGCSXBCS-UHFFFAOYSA-N
MW1661.66 g/mol
LogP6.92
Rot. Bonds12

About 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide

2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide (PubChem CID 157458987) has the molecular formula C78H87Cl2N21O15S and a molecular weight of 1661.66 g/mol. Its IUPAC name is 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide.

Molecular Properties

Compound Name2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide
PubChem CID157458987
Molecular FormulaC78H87Cl2N21O15S
Molecular Weight1661.66 g/mol
Exact Mass1659.58
IUPAC Name2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide
SMILESCc1ccc2[nH]cc(CC(=O)N3CCn4nc(C(=O)NO)cc4C3)c2c1.Cc1nc(CC(=O)N2CCn3nc(C(=O)NO)cc3C2)cs1.Cn1c(C(=O)N2CCn3cc(C(=O)NO)cc3C2)cc(Cl)c1Cl.Cn1ccc2cc(C(=O)N3CCn4cc(C(=O)NO)cc4C3)ccc21.O=C(NO)c1cc2n(c1)CCN(C(=O)C1CCCCC1)C2
InChIInChI=1S/C18H19N5O3.C18H18N4O3.C15H21N3O3.C14H14Cl2N4O3.C13H15N5O3S/c1-11-2-3-15-14(6-11)12(9-19-15)7-17(24)22-4-5-23-13(10-22)8-16(20-23)18(25)21-26;1-20-5-4-12-8-13(2-3-16(12)20)18(24)22-7-6-21-10-14(17(23)19-25)9-15(21)11-22;19-14(16-21)12-8-13-10-18(7-6-17(13)9-12)15(20)11-4-2-1-3-5-11;1-18-11(5-10(15)12(18)16)14(22)20-3-2-19-6-8(13(21)17-23)4-9(19)7-20;1-8-14-9(7-22-8)4-12(19)17-2-3-18-10(6-17)5-11(15-18)13(20)16-21/h2-3,6,8-9,19,26H,4-5,7,10H2,1H3,(H,21,25);2-5,8-10,25H,6-7,11H2,1H3,(H,19,23);8-9,11,21H,1-7,10H2,(H,16,19);4-6,23H,2-3,7H2,1H3,(H,17,21);5,7,21H,2-4,6H2,1H3,(H,16,20)
InChIKeyBTRVJGXGCSXBCS-UHFFFAOYSA-N
XLogP6.92
TPSA437.17 Ų
H-Bond Donors11
H-Bond Acceptors26
Rotatable Bonds12
Heavy Atoms117
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001661.66
LogP ≤ 56.92
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1026

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide?
The IUPAC name of 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide (CID 157458987) is 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide.
What is the SMILES notation for 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide?
The canonical SMILES for 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide is Cc1ccc2[nH]cc(CC(=O)N3CCn4nc(C(=O)NO)cc4C3)c2c1.Cc1nc(CC(=O)N2CCn3nc(C(=O)NO)cc3C2)cs1.Cn1c(C(=O)N2CCn3cc(C(=O)NO)cc3C2)cc(Cl)c1Cl.Cn1ccc2cc(C(=O)N3CCn4cc(C(=O)NO)cc4C3)ccc21.O=C(NO)c1cc2n(c1)CCN(C(=O)C1CCCCC1)C2.
What is the InChIKey of 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide?
The InChIKey is BTRVJGXGCSXBCS-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H19N5O3.C18H18N4O3.C15H21N3O3.C14H14Cl2N4O3.C13H15N5O3S/c1-11-2-3-15-14(6-11)12(9-19-15)7-17(24)22-4-5-23-13(10-22)8-16(20-23)18(25)21-26;1-20-5-4-12-8-13(2-3-16(12)20)18(24)22-7-6-21-10-14(17(23)19-25)9-15(21)11-22;19-14(16-21)12-8-13-10-18(7-6-17(13)9-12)15(20)11-4-2-1-3-5-11;1-18-11(5-10(15)12(18)16)14(22)20-3-2-19-6-8(13(21)17-23)4-9(19)7-20;1-8-14-9(7-22-8)4-12(19)17-2-3-18-10(6-17)5-11(15-18)13(20)16-21/h2-3,6,8-9,19,26H,4-5,7,10H2,1H3,(H,21,25);2-5,8-10,25H,6-7,11H2,1H3,(H,19,23);8-9,11,21H,1-7,10H2,(H,16,19);4-6,23H,2-3,7H2,1H3,(H,17,21);5,7,21H,2-4,6H2,1H3,(H,16,20).
What are the key properties of 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide?
2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide has a molecular weight of 1661.66 g/mol, XLogP of 6.92, 12 rotatable bonds, 11 hydrogen bond donors, and 26 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;2-(4,5-dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide;N-hydroxy-5-[2-(5-methyl-1H-indol-3-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide;N-hydroxy-5-[2-(2-methyl-1,3-thiazol-4-yl)acetyl]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide is sourced from PubChem (CID 157458987), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).