2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide

C133H169FN36O12 — CID 157461363

About 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide

2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide (PubChem CID 157461363) has the molecular formula C133H169FN36O12 and a molecular weight of 2483.05 g/mol. Its IUPAC name is 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide.

Molecular Properties

• Compound Name: 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide
• PubChem CID: 157461363
• Molecular Formula: C133H169FN36O12
• Molecular Weight: 2483.05 g/mol
• Exact Mass: 2481.37
• IUPAC Name: 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide
• SMILES: CCC(CC)n1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21.Cc1[nH]c2ccccc2c1CNCC1CCN(c2ncc(C(=O)NO)cn2)CC1.Cc1ccc2c(c1)c(CNCC1CCN(c3ncc(C(=O)NO)cn3)CC1)cn2C.Cc1cccc2c(CNCC3CCN(c4ncc(C(=O)NO)cn4)CC3)cn(C)c12.Cc1cccc2c1c(CNCC1CCN(c3ncc(C(=O)NO)cn3)CC1)cn2C.Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2c(F)cccc21
• InChI: InChI=1S/C25H34N6O2.3C22H28N6O2.C21H25FN6O2.C21H26N6O2/c1-3-21(4-2)31-17-20(22-7-5-6-8-23(22)31)14-26-13-18-9-11-30(12-10-18)25-27-15-19(16-28-25)24(32)29-33;1-15-3-4-20-19(9-15)18(14-27(20)2)11-23-10-16-5-7-28(8-6-16)22-24-12-17(13-25-22)21(29)26-30;1-15-4-3-5-19-20(15)18(14-27(19)2)11-23-10-16-6-8-28(9-7-16)22-24-12-17(13-25-22)21(29)26-30;1-15-4-3-5-19-18(14-27(2)20(15)19)11-23-10-16-6-8-28(9-7-16)22-24-12-17(13-25-22)21(29)26-30;1-27-13-16(19-17(22)3-2-4-18(19)27)10-23-9-14-5-7-28(8-6-14)21-24-11-15(12-25-21)20(29)26-30;1-14-18(17-4-2-3-5-19(17)25-14)13-22-10-15-6-8-27(9-7-15)21-23-11-16(12-24-21)20(28)26-29/h5-8,15-18,21,26,33H,3-4,9-14H2,1-2H3,(H,29,32);3-4,9,12-14,16,23,30H,5-8,10-11H2,1-2H3,(H,26,29);2*3-5,12-14,16,23,30H,6-11H2,1-2H3,(H,26,29);2-4,11-14,23,30H,5-10H2,1H3,(H,26,29);2-5,11-12,15,22,25,29H,6-10,13H2,1H3,(H,26,28)
• InChIKey: BTYQVTKQBJFQHV-UHFFFAOYSA-N
• XLogP: 15.75
• TPSA: 582.72 Ų
• H-Bond Donors: 19
• H-Bond Acceptors: 41
• Rotatable Bonds: 39
• Heavy Atoms: 182
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2483.05
LogP ≤ 5	15.75
H-Bond Donors ≤ 5	19
H-Bond Acceptors ≤ 10	41

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'indol_3yl_alk(461)', 'substructure': 'N/A'}, {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide?

The IUPAC name of 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide (CID 157461363) is 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide.

What is the SMILES notation for 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide?

The canonical SMILES for 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide is CCC(CC)n1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2ccccc21.Cc1[nH]c2ccccc2c1CNCC1CCN(c2ncc(C(=O)NO)cn2)CC1.Cc1ccc2c(c1)c(CNCC1CCN(c3ncc(C(=O)NO)cn3)CC1)cn2C.Cc1cccc2c(CNCC3CCN(c4ncc(C(=O)NO)cn4)CC3)cn(C)c12.Cc1cccc2c1c(CNCC1CCN(c3ncc(C(=O)NO)cn3)CC1)cn2C.Cn1cc(CNCC2CCN(c3ncc(C(=O)NO)cn3)CC2)c2c(F)cccc21.

What is the InChIKey of 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide?

The InChIKey is BTYQVTKQBJFQHV-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H34N6O2.3C22H28N6O2.C21H25FN6O2.C21H26N6O2/c1-3-21(4-2)31-17-20(22-7-5-6-8-23(22)31)14-26-13-18-9-11-30(12-10-18)25-27-15-19(16-28-25)24(32)29-33;1-15-3-4-20-19(9-15)18(14-27(20)2)11-23-10-16-5-7-28(8-6-16)22-24-12-17(13-25-22)21(29)26-30;1-15-4-3-5-19-20(15)18(14-27(19)2)11-23-10-16-6-8-28(9-7-16)22-24-12-17(13-25-22)21(29)26-30;1-15-4-3-5-19-18(14-27(2)20(15)19)11-23-10-16-6-8-28(9-7-16)22-24-12-17(13-25-22)21(29)26-30;1-27-13-16(19-17(22)3-2-4-18(19)27)10-23-9-14-5-7-28(8-6-14)21-24-11-15(12-25-21)20(29)26-30;1-14-18(17-4-2-3-5-19(17)25-14)13-22-10-15-6-8-27(9-7-15)21-23-11-16(12-24-21)20(28)26-29/h5-8,15-18,21,26,33H,3-4,9-14H2,1-2H3,(H,29,32);3-4,9,12-14,16,23,30H,5-8,10-11H2,1-2H3,(H,26,29);2*3-5,12-14,16,23,30H,6-11H2,1-2H3,(H,26,29);2-4,11-14,23,30H,5-10H2,1H3,(H,26,29);2-5,11-12,15,22,25,29H,6-10,13H2,1H3,(H,26,28).

What are the key properties of 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide?

2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide has a molecular weight of 2483.05 g/mol, XLogP of 15.75, 39 rotatable bonds, 19 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[4-[[(1,4-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,5-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(1,7-dimethylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;2-[4-[[(4-fluoro-1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(2-methyl-1H-indol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[4-[[(1-pentan-3-ylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide is sourced from PubChem (CID 157461363), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).