(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one

C124H122F10N30O6 — CID 157463793

IUPAC(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one
SMILESC[C@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)cn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)nn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)cn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)nn1
InChIInChI=1S/C26H28F2N4O2.2C25H24F2N6O.2C24H23F2N7O/c1-14-26(33)31(2)13-21-23(30-25(32(14)21)16-6-7-16)17-4-3-5-20-18(17)12-19(24(27)28)22(29-20)15-8-10-34-11-9-15;2*1-13-10-32(12-28-13)24-18(22(26)27)9-17-16(5-4-6-19(17)29-24)21-20-11-31(3)25(34)14(2)33(20)23(30-21)15-7-8-15;2*1-12-10-32(30-29-12)23-17(21(25)26)9-16-15(5-4-6-18(16)27-23)20-19-11-31(3)24(34)13(2)33(19)22(28-20)14-7-8-14/h3-5,12,14-16,24H,6-11,13H2,1-2H3;2*4-6,9-10,12,14-15,22H,7-8,11H2,1-3H3;2*4-6,9-10,13-14,21H,7-8,11H2,1-3H3/t3*14-;2*13-/m01010/s1
InChIKeyBUFUQYJIMHZYQL-CYKGZOIZSA-N
MW2318.52 g/mol
LogP23.89
Rot. Bonds20

About (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one

(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one (PubChem CID 157463793) has the molecular formula C124H122F10N30O6 and a molecular weight of 2318.52 g/mol. Its IUPAC name is (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one.

Molecular Properties

Compound Name(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one
PubChem CID157463793
Molecular FormulaC124H122F10N30O6
Molecular Weight2318.52 g/mol
Exact Mass2317.00
IUPAC Name(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one
SMILESC[C@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)cn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)nn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)cn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)nn1
InChIInChI=1S/C26H28F2N4O2.2C25H24F2N6O.2C24H23F2N7O/c1-14-26(33)31(2)13-21-23(30-25(32(14)21)16-6-7-16)17-4-3-5-20-18(17)12-19(24(27)28)22(29-20)15-8-10-34-11-9-15;2*1-13-10-32(12-28-13)24-18(22(26)27)9-17-16(5-4-6-19(17)29-24)21-20-11-31(3)25(34)14(2)33(20)23(30-21)15-7-8-15;2*1-12-10-32(30-29-12)23-17(21(25)26)9-16-15(5-4-6-18(16)27-23)20-19-11-31(3)24(34)13(2)33(19)22(28-20)14-7-8-14/h3-5,12,14-16,24H,6-11,13H2,1-2H3;2*4-6,9-10,12,14-15,22H,7-8,11H2,1-3H3;2*4-6,9-10,13-14,21H,7-8,11H2,1-3H3/t3*14-;2*13-/m01010/s1
InChIKeyBUFUQYJIMHZYQL-CYKGZOIZSA-N
XLogP23.89
TPSA361.39 Ų
H-Bond Donors
H-Bond Acceptors31
Rotatable Bonds20
Heavy Atoms170
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002318.52
LogP ≤ 523.89
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1031

Analyze (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

3-[2-[[5-(3-cyclopropyl-7-methyl-6-oxo-5,8-dihydroimidazo[1,5-a]pyrazin-1-yl)-3-(1-methylpyrazol-4-yl)indazol-1-yl]methyl]cyclopropyl]-1-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one
CID 139570970
(6-Cyclopropylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(6-methylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(6-pyrrolidin-1-ylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(6-pyrrol-1-ylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 157508524
3-(3,3-difluorocyclobutyl)-1-[3-(difluoromethyl)-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-N-methyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;3-(4,4-difluorocyclohexyl)-1-[3-(difluoromethyl)-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-N-methyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;3-(2,2-difluorocyclopropyl)-1-[3-(difluoromethyl)-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-N-methyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide
CID 157762464
1-[3-cyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-3-(3,3-difluorocyclobutyl)-N-methyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;3-(3,3-difluorocyclobutyl)-N-methyl-1-(3-morpholin-4-ylisoquinolin-8-yl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;N-methyl-1-[2-(1-methylpyrazol-4-yl)-3-(trifluoromethyl)quinolin-5-yl]-3-(oxan-4-yl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide
CID 157854620
1-[3-(3,3-difluorocyclobutyl)-1-[3-(1,3-dimethylpyrazol-4-yl)-7-methylisoquinolin-8-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-3-(4-fluoro-4-methylcyclohexyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[3-(3-fluoro-3-methylcyclobutyl)-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[3-(4-fluoro-4-methylcyclohexyl)-1-[3-methyl-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one
CID 158102377
3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)-7-methylisoquinolin-8-yl]-N-methyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;3-cyclopropyl-N-methyl-1-[7-methyl-3-(oxan-4-yl)isoquinolin-8-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;3-(4,4-difluorocyclohexyl)-N-methyl-1-(3-morpholin-4-ylisoquinolin-8-yl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;1-[3-(1,3-dimethylpyrazol-4-yl)-7-methylisoquinolin-8-yl]-N-methyl-3-(oxan-4-yl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide
CID 158202317
(6-Cyclopropylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;imidazo[1,2-b]pyridazin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis((6-methylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);(6-pyrrolidin-1-ylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 158376602
1-[3-cyclopropyl-1-[3-methyl-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[3-(3,3-difluorocyclopentyl)-1-[3-methyl-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[3-(2,2-difluorocyclopropyl)-1-[3-methyl-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[1-(3-morpholin-4-ylisoquinolin-8-yl)-3-(oxan-4-yl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one
CID 158953891
3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-N-methyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;3-(3,3-difluorocyclobutyl)-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-N-methyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-N-methyl-3-(oxan-4-yl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide;N-methyl-3-(oxan-4-yl)-1-[3-(oxan-4-yl)isoquinolin-8-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxamide
CID 159317607
1-[3-cyclopropyl-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[3-cyclopropyl-1-[7-methyl-3-(2-methyl-1,3-thiazol-5-yl)isoquinolin-8-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[3-cyclopropyl-1-[3-(oxan-4-yl)isoquinolin-8-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one;1-[3-(3,3-difluorocyclobutyl)-1-[3-methyl-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]propan-1-one
CID 159782323
(6-Cyclopropylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis((6-methylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);(6-pyrrolidin-1-ylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(6-pyrrol-1-ylimidazo[1,2-b]pyridazin-2-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 160109032
1-[(2R)-4-[7-(2,3-dimethylphenyl)-2-[[(2S,4R)-1,4-dimethylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-2-(isocyanomethyl)piperazin-1-yl]prop-2-en-1-one;1-[(2R)-2-(isocyanomethyl)-4-[7-(1-methylindol-7-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one;1-[(2R)-2-(isocyanomethyl)-4-[2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7-[8-(trifluoromethyl)naphthalen-1-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one;1-[(2S)-2-(2-methoxyethyl)-4-[2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-7-naphthalen-1-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one
CID 160374355

Frequently Asked Questions

What is the IUPAC name of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?
The IUPAC name of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one (CID 157463793) is (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one.
What is the SMILES notation for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?
The canonical SMILES for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one is C[C@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)cn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)nn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)cn1.Cc1cn(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)nn1.
What is the InChIKey of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?
The InChIKey is BUFUQYJIMHZYQL-CYKGZOIZSA-N. The full InChI is InChI=1S/C26H28F2N4O2.2C25H24F2N6O.2C24H23F2N7O/c1-14-26(33)31(2)13-21-23(30-25(32(14)21)16-6-7-16)17-4-3-5-20-18(17)12-19(24(27)28)22(29-20)15-8-10-34-11-9-15;2*1-13-10-32(12-28-13)24-18(22(26)27)9-17-16(5-4-6-19(17)29-24)21-20-11-31(3)25(34)14(2)33(20)23(30-21)15-7-8-15;2*1-12-10-32(30-29-12)23-17(21(25)26)9-16-15(5-4-6-18(16)27-23)20-19-11-31(3)24(34)13(2)33(19)22(28-20)14-7-8-14/h3-5,12,14-16,24H,6-11,13H2,1-2H3;2*4-6,9-10,12,14-15,22H,7-8,11H2,1-3H3;2*4-6,9-10,13-14,21H,7-8,11H2,1-3H3/t3*14-;2*13-/m01010/s1.
What are the key properties of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?
(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one has a molecular weight of 2318.52 g/mol, XLogP of 23.89, 20 rotatable bonds, 0 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methylimidazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(4-methyltriazol-1-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one is sourced from PubChem (CID 157463793), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).