5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide

C110H121FN40O8 — CID 157463810

About 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide

5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide (PubChem CID 157463810) has the molecular formula C110H121FN40O8 and a molecular weight of 2150.45 g/mol. Its IUPAC name is 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide.

Molecular Properties

• Compound Name: 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide
• PubChem CID: 157463810
• Molecular Formula: C110H121FN40O8
• Molecular Weight: 2150.45 g/mol
• Exact Mass: 2149.03
• IUPAC Name: 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide
• SMILES: CC(C)c1cnc(C(=O)NC2(CO)CCN(c3nccn4cccc34)C2)nc1.CC(C)c1cnc(C(=O)N[C@H]2CCN(c3nccn4ccnc34)C2)nc1.CC(C)c1cnc(C(=O)N[C@H]2CCN(c3nccn4cnnc34)C2)nc1.CCc1cnc(C(=O)N[C@H]2CCN(c3nccn4ccnc34)C2)nc1.Cc1cnc(C(=O)N[C@H]2CCN(c3nccn4cccc34)C2)nc1.O=C(N[C@@H]1CN(c2nccn3cccc23)CC1O)c1ccn(-c2ccc(F)cc2)n1
• InChI: InChI=1S/C21H19FN6O2.C20H24N6O2.C18H21N7O.C17H20N8O.C17H19N7O.C17H18N6O/c22-14-3-5-15(6-4-14)28-10-7-16(25-28)21(30)24-17-12-27(13-19(17)29)20-18-2-1-9-26(18)11-8-23-20;1-14(2)15-10-22-17(23-11-15)19(28)24-20(13-27)5-8-26(12-20)18-16-4-3-7-25(16)9-6-21-18;1-12(2)13-9-21-15(22-10-13)18(26)23-14-3-6-25(11-14)17-16-19-4-7-24(16)8-5-20-17;1-11(2)12-7-19-14(20-8-12)17(26)22-13-3-5-24(9-13)15-16-23-21-10-25(16)6-4-18-15;1-2-12-9-20-14(21-10-12)17(25)22-13-3-6-24(11-13)16-15-18-4-7-23(15)8-5-19-16;1-12-9-19-15(20-10-12)17(24)21-13-4-7-23(11-13)16-14-3-2-6-22(14)8-5-18-16/h1-11,17,19,29H,12-13H2,(H,24,30);3-4,6-7,9-11,14,27H,5,8,12-13H2,1-2H3,(H,24,28);4-5,7-10,12,14H,3,6,11H2,1-2H3,(H,23,26);4,6-8,10-11,13H,3,5,9H2,1-2H3,(H,22,26);4-5,7-10,13H,2-3,6,11H2,1H3,(H,22,25);2-3,5-6,8-10,13H,4,7,11H2,1H3,(H,21,24)/t17-,19?;;14-;3*13-/m1.0000/s1
• InChIKey: BUFVYPHXMYJYCJ-NMHPCHQPSA-N
• XLogP: 8.49
• TPSA: 536.58 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 42
• Rotatable Bonds: 24
• Heavy Atoms: 159
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2150.45
LogP ≤ 5	8.49
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	42

Frequently Asked Questions

What is the IUPAC name of 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide?

The IUPAC name of 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide (CID 157463810) is 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide.

What is the SMILES notation for 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide?

The canonical SMILES for 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide is CC(C)c1cnc(C(=O)NC2(CO)CCN(c3nccn4cccc34)C2)nc1.CC(C)c1cnc(C(=O)N[C@H]2CCN(c3nccn4ccnc34)C2)nc1.CC(C)c1cnc(C(=O)N[C@H]2CCN(c3nccn4cnnc34)C2)nc1.CCc1cnc(C(=O)N[C@H]2CCN(c3nccn4ccnc34)C2)nc1.Cc1cnc(C(=O)N[C@H]2CCN(c3nccn4cccc34)C2)nc1.O=C(N[C@@H]1CN(c2nccn3cccc23)CC1O)c1ccn(-c2ccc(F)cc2)n1.

What is the InChIKey of 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide?

The InChIKey is BUFVYPHXMYJYCJ-NMHPCHQPSA-N. The full InChI is InChI=1S/C21H19FN6O2.C20H24N6O2.C18H21N7O.C17H20N8O.C17H19N7O.C17H18N6O/c22-14-3-5-15(6-4-14)28-10-7-16(25-28)21(30)24-17-12-27(13-19(17)29)20-18-2-1-9-26(18)11-8-23-20;1-14(2)15-10-22-17(23-11-15)19(28)24-20(13-27)5-8-26(12-20)18-16-4-3-7-25(16)9-6-21-18;1-12(2)13-9-21-15(22-10-13)18(26)23-14-3-6-25(11-14)17-16-19-4-7-24(16)8-5-20-17;1-11(2)12-7-19-14(20-8-12)17(26)22-13-3-5-24(9-13)15-16-23-21-10-25(16)6-4-18-15;1-2-12-9-20-14(21-10-12)17(25)22-13-3-6-24(11-13)16-15-18-4-7-23(15)8-5-19-16;1-12-9-19-15(20-10-12)17(24)21-13-4-7-23(11-13)16-14-3-2-6-22(14)8-5-18-16/h1-11,17,19,29H,12-13H2,(H,24,30);3-4,6-7,9-11,14,27H,5,8,12-13H2,1-2H3,(H,24,28);4-5,7-10,12,14H,3,6,11H2,1-2H3,(H,23,26);4,6-8,10-11,13H,3,5,9H2,1-2H3,(H,22,26);4-5,7-10,13H,2-3,6,11H2,1H3,(H,22,25);2-3,5-6,8-10,13H,4,7,11H2,1H3,(H,21,24)/t17-,19?;;14-;3*13-/m1.0000/s1.

What are the key properties of 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide?

5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide has a molecular weight of 2150.45 g/mol, XLogP of 8.49, 24 rotatable bonds, 8 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 5-ethyl-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;1-(4-fluorophenyl)-N-[(3R)-4-hydroxy-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide;N-[3-(hydroxymethyl)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-5-propan-2-ylpyrimidine-2-carboxamide;5-methyl-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrimidine-2-carboxamide;5-propan-2-yl-N-[(3S)-1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)pyrrolidin-3-yl]pyrimidine-2-carboxamide is sourced from PubChem (CID 157463810), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).