2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide

C110H116F5N17O6 — CID 157466369

IUPAC2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide
SMILESCC1=C(c2ccc(NC(=O)C(C)C)nc2)C2(CC1)CC2.CC1=C(c2ccc(NC(=O)c3c(F)cncc3F)nc2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)C(C)C)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3c(F)cccc3F)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3ccccc3C)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3ccccc3F)cn2)C2(CC1)CC2
InChIInChI=1S/C20H21N3O.2C19H17F2N3O.C19H18FN3O.C17H22N2O.C16H21N3O/c1-13-5-3-4-6-15(13)19(24)23-17-12-21-16(11-22-17)18-14(2)7-8-20(18)9-10-20;1-11-4-5-19(6-7-19)17(11)12-2-3-15(23-8-12)24-18(25)16-13(20)9-22-10-14(16)21;1-11-5-6-19(7-8-19)17(11)14-9-23-15(10-22-14)24-18(25)16-12(20)3-2-4-13(16)21;1-12-6-7-19(8-9-19)17(12)15-10-22-16(11-21-15)23-18(24)13-4-2-3-5-14(13)20;1-11(2)16(20)19-14-5-4-13(10-18-14)15-12(3)6-7-17(15)8-9-17;1-10(2)15(20)19-13-9-17-12(8-18-13)14-11(3)4-5-16(14)6-7-16/h3-6,11-12H,7-10H2,1-2H3,(H,22,23,24);2-3,8-10H,4-7H2,1H3,(H,23,24,25);2-4,9-10H,5-8H2,1H3,(H,23,24,25);2-5,10-11H,6-9H2,1H3,(H,22,23,24);4-5,10-11H,6-9H2,1-3H3,(H,18,19,20);8-10H,4-7H2,1-3H3,(H,18,19,20)
InChIKeyBUNJAQQFNGHBHW-UHFFFAOYSA-N
MW1867.24 g/mol
LogP24.75
Rot. Bonds18

About 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide

2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide (PubChem CID 157466369) has the molecular formula C110H116F5N17O6 and a molecular weight of 1867.24 g/mol. Its IUPAC name is 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide.

Molecular Properties

Compound Name2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide
PubChem CID157466369
Molecular FormulaC110H116F5N17O6
Molecular Weight1867.24 g/mol
Exact Mass1865.92
IUPAC Name2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide
SMILESCC1=C(c2ccc(NC(=O)C(C)C)nc2)C2(CC1)CC2.CC1=C(c2ccc(NC(=O)c3c(F)cncc3F)nc2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)C(C)C)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3c(F)cccc3F)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3ccccc3C)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3ccccc3F)cn2)C2(CC1)CC2
InChIInChI=1S/C20H21N3O.2C19H17F2N3O.C19H18FN3O.C17H22N2O.C16H21N3O/c1-13-5-3-4-6-15(13)19(24)23-17-12-21-16(11-22-17)18-14(2)7-8-20(18)9-10-20;1-11-4-5-19(6-7-19)17(11)12-2-3-15(23-8-12)24-18(25)16-13(20)9-22-10-14(16)21;1-11-5-6-19(7-8-19)17(11)14-9-23-15(10-22-14)24-18(25)16-12(20)3-2-4-13(16)21;1-12-6-7-19(8-9-19)17(12)15-10-22-16(11-21-15)23-18(24)13-4-2-3-5-14(13)20;1-11(2)16(20)19-14-5-4-13(10-18-14)15-12(3)6-7-17(15)8-9-17;1-10(2)15(20)19-13-9-17-12(8-18-13)14-11(3)4-5-16(14)6-7-16/h3-6,11-12H,7-10H2,1-2H3,(H,22,23,24);2-3,8-10H,4-7H2,1H3,(H,23,24,25);2-4,9-10H,5-8H2,1H3,(H,23,24,25);2-5,10-11H,6-9H2,1H3,(H,22,23,24);4-5,10-11H,6-9H2,1-3H3,(H,18,19,20);8-10H,4-7H2,1-3H3,(H,18,19,20)
InChIKeyBUNJAQQFNGHBHW-UHFFFAOYSA-N
XLogP24.75
TPSA316.39 Ų
H-Bond Donors6
H-Bond Acceptors17
Rotatable Bonds18
Heavy Atoms138
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001867.24
LogP ≤ 524.75
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1017

Analyze 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide with MolForge

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Related Compounds

N-(5-(3-(cyclopropanecarboxamido)isoquinolin-7-yl)-6-methylpyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide
CID 71115180
US20240043448, Example 19a
CID 156295593
US12319655, Example 433
CID 168929262
US12319655, Example 454
CID 168929489
US12319655, Example 276
CID 168929534
US12319655, Example 466
CID 168929535
US12319655, Example 271
CID 168929837
US12319655, Example 275
CID 168930169
US20240043448, Example 19b
CID 171362513
6-[5-(2-amino-2-oxo-1-pyridin-3-ylethyl)-6-[2-(3-fluorophenyl)ethylamino]-2-pyridinyl]-2-[2-(3-fluorophenyl)ethylamino]-N-(pyridin-3-ylmethyl)pyridine-3-carboxamide
CID 67101814
1-[1-[[6-(2-fluorophenyl)-5-(3-fluoro-4-pyridinyl)pyrazin-2-yl]carbamoyl]cyclopropyl]-N-[5-(3-fluoro-4-pyridinyl)-6-(5-fluoro-2-pyridinyl)pyrazin-2-yl]cyclopropane-1-carboxamide
CID 69149862
[(7S)-7-[[(4,6-dimethylpyrimidin-2-yl)amino]methyl]-6-azaspiro[2.5]octan-6-yl]-(2-phenylphenyl)methanone;(5-methyl-2-pyrimidin-2-ylphenyl)-[(7S)-7-[[[6-(trifluoromethyl)-2-pyridinyl]amino]methyl]-6-azaspiro[2.5]octan-6-yl]methanone
CID 87180376

Frequently Asked Questions

What is the IUPAC name of 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide?
The IUPAC name of 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide (CID 157466369) is 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide.
What is the SMILES notation for 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide?
The canonical SMILES for 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide is CC1=C(c2ccc(NC(=O)C(C)C)nc2)C2(CC1)CC2.CC1=C(c2ccc(NC(=O)c3c(F)cncc3F)nc2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)C(C)C)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3c(F)cccc3F)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3ccccc3C)cn2)C2(CC1)CC2.CC1=C(c2cnc(NC(=O)c3ccccc3F)cn2)C2(CC1)CC2.
What is the InChIKey of 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide?
The InChIKey is BUNJAQQFNGHBHW-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H21N3O.2C19H17F2N3O.C19H18FN3O.C17H22N2O.C16H21N3O/c1-13-5-3-4-6-15(13)19(24)23-17-12-21-16(11-22-17)18-14(2)7-8-20(18)9-10-20;1-11-4-5-19(6-7-19)17(11)12-2-3-15(23-8-12)24-18(25)16-13(20)9-22-10-14(16)21;1-11-5-6-19(7-8-19)17(11)14-9-23-15(10-22-14)24-18(25)16-12(20)3-2-4-13(16)21;1-12-6-7-19(8-9-19)17(12)15-10-22-16(11-21-15)23-18(24)13-4-2-3-5-14(13)20;1-11(2)16(20)19-14-5-4-13(10-18-14)15-12(3)6-7-17(15)8-9-17;1-10(2)15(20)19-13-9-17-12(8-18-13)14-11(3)4-5-16(14)6-7-16/h3-6,11-12H,7-10H2,1-2H3,(H,22,23,24);2-3,8-10H,4-7H2,1H3,(H,23,24,25);2-4,9-10H,5-8H2,1H3,(H,23,24,25);2-5,10-11H,6-9H2,1H3,(H,22,23,24);4-5,10-11H,6-9H2,1-3H3,(H,18,19,20);8-10H,4-7H2,1-3H3,(H,18,19,20).
What are the key properties of 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide?
2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide has a molecular weight of 1867.24 g/mol, XLogP of 24.75, 18 rotatable bonds, 6 hydrogen bond donors, and 17 hydrogen bond acceptors.
Where does this data come from?
All data for 2,6-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;3,5-difluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]pyridine-4-carboxamide;2-fluoro-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)pyrazin-2-yl]propanamide;2-methyl-N-[5-(6-methylspiro[2.4]hept-6-en-7-yl)-2-pyridinyl]propanamide is sourced from PubChem (CID 157466369), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).