2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

C154H174N30O24S2 — CID 157494531

About 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide (PubChem CID 157494531) has the molecular formula C154H174N30O24S2 and a molecular weight of 2893.41 g/mol. Its IUPAC name is 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide.

Molecular Properties

• Compound Name: 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
• PubChem CID: 157494531
• Molecular Formula: C154H174N30O24S2
• Molecular Weight: 2893.41 g/mol
• Exact Mass: 2891.28
• IUPAC Name: 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
• SMILES: C=CC(=O)Cc1cc(-c2nn(C3CCN(CC(=O)NCCCCCC(=O)COc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)c3ncnc(N)c23)ccc1Oc1ccccc1.C=CC(=O)Nc1cc(-c2nn(C3CCN(CC(=O)C[C@@H](C(=O)N4C[C@@H](O)C[C@@H]4C(=O)NCc4ccc(-c5scnc5C)cc4)C(C)(C)C)CC3)c3ncnc(N)c23)ccc1Oc1ccccc1.C=CC(=O)Nc1cc(-c2nn(C3CCN(CCOCCOCCOCCC(=O)N[C@@H](C(=O)N4C[C@@H](O)C[C@@H]4C(=O)NCc4ccc(-c5scnc5C)cc4)C(C)(C)C)CC3)c3ncnc(N)c23)ccc1Oc1ccccc1
• InChI: InChI=1S/C56H69N11O9S.C50H56N10O6S.C48H49N9O9/c1-6-46(69)62-43-30-39(16-17-45(43)76-42-10-8-7-9-11-42)49-48-52(57)59-34-60-53(48)67(64-49)40-18-21-65(22-19-40)23-25-74-27-29-75-28-26-73-24-20-47(70)63-51(56(3,4)5)55(72)66-33-41(68)31-44(66)54(71)58-32-37-12-14-38(15-13-37)50-36(2)61-35-77-50;1-6-42(63)56-39-22-33(16-17-41(39)66-37-10-8-7-9-11-37)44-43-46(51)53-28-54-47(43)60(57-44)34-18-20-58(21-19-34)26-35(61)23-38(50(3,4)5)49(65)59-27-36(62)24-40(59)48(64)52-25-31-12-14-32(15-13-31)45-30(2)55-29-67-45;1-2-32(58)25-30-24-29(15-17-37(30)66-34-11-6-3-7-12-34)43-42-44(49)51-28-52-45(42)57(54-43)31-19-22-55(23-20-31)26-40(61)50-21-8-4-5-10-33(59)27-65-38-14-9-13-35-41(38)48(64)56(47(35)63)36-16-18-39(60)53-46(36)62/h6-17,30,34-35,40-41,44,51,68H,1,18-29,31-33H2,2-5H3,(H,58,71)(H,62,69)(H,63,70)(H2,57,59,60);6-17,22,28-29,34,36,38,40,62H,1,18-21,23-27H2,2-5H3,(H,52,64)(H,56,63)(H2,51,53,54);2-3,6-7,9,11-15,17,24,28,31,36H,1,4-5,8,10,16,18-23,25-27H2,(H,50,61)(H2,49,51,52)(H,53,60,62)/t41-,44+,51-;36-,38-,40+;/m00./s1
• InChIKey: BXQZWVVMFCGHGE-FLKSHIDISA-N
• XLogP: 17.80
• TPSA: 699.41 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 46
• Rotatable Bonds: 58
• Heavy Atoms: 210
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2893.41
LogP ≤ 5	17.80
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	46

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}, {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide?

The IUPAC name of 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide (CID 157494531) is 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide.

What is the SMILES notation for 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide?

The canonical SMILES for 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide is C=CC(=O)Cc1cc(-c2nn(C3CCN(CC(=O)NCCCCCC(=O)COc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)c3ncnc(N)c23)ccc1Oc1ccccc1.C=CC(=O)Nc1cc(-c2nn(C3CCN(CC(=O)C[C@@H](C(=O)N4C[C@@H](O)C[C@@H]4C(=O)NCc4ccc(-c5scnc5C)cc4)C(C)(C)C)CC3)c3ncnc(N)c23)ccc1Oc1ccccc1.C=CC(=O)Nc1cc(-c2nn(C3CCN(CCOCCOCCOCCC(=O)N[C@@H](C(=O)N4C[C@@H](O)C[C@@H]4C(=O)NCc4ccc(-c5scnc5C)cc4)C(C)(C)C)CC3)c3ncnc(N)c23)ccc1Oc1ccccc1.

What is the InChIKey of 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide?

The InChIKey is BXQZWVVMFCGHGE-FLKSHIDISA-N. The full InChI is InChI=1S/C56H69N11O9S.C50H56N10O6S.C48H49N9O9/c1-6-46(69)62-43-30-39(16-17-45(43)76-42-10-8-7-9-11-42)49-48-52(57)59-34-60-53(48)67(64-49)40-18-21-65(22-19-40)23-25-74-27-29-75-28-26-73-24-20-47(70)63-51(56(3,4)5)55(72)66-33-41(68)31-44(66)54(71)58-32-37-12-14-38(15-13-37)50-36(2)61-35-77-50;1-6-42(63)56-39-22-33(16-17-41(39)66-37-10-8-7-9-11-37)44-43-46(51)53-28-54-47(43)60(57-44)34-18-20-58(21-19-34)26-35(61)23-38(50(3,4)5)49(65)59-27-36(62)24-40(59)48(64)52-25-31-12-14-32(15-13-31)45-30(2)55-29-67-45;1-2-32(58)25-30-24-29(15-17-37(30)66-34-11-6-3-7-12-34)43-42-44(49)51-28-52-45(42)57(54-43)31-19-22-55(23-20-31)26-40(61)50-21-8-4-5-10-33(59)27-65-38-14-9-13-35-41(38)48(64)56(47(35)63)36-16-18-39(60)53-46(36)62/h6-17,30,34-35,40-41,44,51,68H,1,18-29,31-33H2,2-5H3,(H,58,71)(H,62,69)(H,63,70)(H2,57,59,60);6-17,22,28-29,34,36,38,40,62H,1,18-21,23-27H2,2-5H3,(H,52,64)(H,56,63)(H2,51,53,54);2-3,6-7,9,11-15,17,24,28,31,36H,1,4-5,8,10,16,18-23,25-27H2,(H,50,61)(H2,49,51,52)(H,53,60,62)/t41-,44+,51-;36-,38-,40+;/m00./s1.

What are the key properties of 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide?

2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide has a molecular weight of 2893.41 g/mol, XLogP of 17.80, 58 rotatable bonds, 12 hydrogen bond donors, and 46 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[4-[4-amino-3-[3-(2-oxobut-3-enyl)-4-phenoxyphenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-N-[7-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxy-6-oxoheptyl]acetamide;(2R,4S)-1-[(2R)-5-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2-tert-butyl-4-oxopentanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;(2R,4S)-1-[(2R)-2-[3-[2-[2-[2-[4-[4-amino-3-[4-phenoxy-3-(prop-2-enoylamino)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide is sourced from PubChem (CID 157494531), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).