N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide

C116H216F5N23O12 — CID 158000426

About N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide

N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide (PubChem CID 158000426) has the molecular formula C116H216F5N23O12 and a molecular weight of 2220.14 g/mol. Its IUPAC name is N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide.

Molecular Properties

• Compound Name: N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide
• PubChem CID: 158000426
• Molecular Formula: C116H216F5N23O12
• Molecular Weight: 2220.14 g/mol
• Exact Mass: 2218.69
• IUPAC Name: N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide
• SMILES: CC(C)(C)N1CCC(NC(=O)N2CC3COCC3C2)CC1.CC(C)(C)N1CCC(NC(=O)N2CCC(F)(F)CC2)CC1.CC(C)(C)N1CCC(NC(=O)N2CCC(O)CC2)CC1.CC(C)N1CCC(NC(=O)C2CCOCC2)CC1.CC(C)N1CCC(NC(=O)N2CCCC(F)(F)C2)CC1.CC(C)N1CCC(NC(=O)N2CCCC(F)C2)CC1.CC(C)N1CCC(NC(=O)N2CCOCC2)CC1.CC1CCN(C(=O)NC2CCN(C(C)C)CC2)CC1
• InChI: InChI=1S/C16H29N3O2.C15H27F2N3O.C15H29N3O2.C15H29N3O.C14H25F2N3O.C14H26FN3O.C14H26N2O2.C13H25N3O2/c1-16(2,3)19-6-4-14(5-7-19)17-15(20)18-8-12-10-21-11-13(12)9-18;1-14(2,3)20-8-4-12(5-9-20)18-13(21)19-10-6-15(16,17)7-11-19;1-15(2,3)18-10-4-12(5-11-18)16-14(20)17-8-6-13(19)7-9-17;1-12(2)17-10-6-14(7-11-17)16-15(19)18-8-4-13(3)5-9-18;1-11(2)18-8-4-12(5-9-18)17-13(20)19-7-3-6-14(15,16)10-19;1-11(2)17-8-5-13(6-9-17)16-14(19)18-7-3-4-12(15)10-18;1-11(2)16-7-3-13(4-8-16)15-14(17)12-5-9-18-10-6-12;1-11(2)15-5-3-12(4-6-15)14-13(17)16-7-9-18-10-8-16/h12-14H,4-11H2,1-3H3,(H,17,20);12H,4-11H2,1-3H3,(H,18,21);12-13,19H,4-11H2,1-3H3,(H,16,20);12-14H,4-11H2,1-3H3,(H,16,19);11-12H,3-10H2,1-2H3,(H,17,20);11-13H,3-10H2,1-2H3,(H,16,19);11-13H,3-10H2,1-2H3,(H,15,17);11-12H,3-10H2,1-2H3,(H,14,17)
• InChIKey: FDQYPQVXRFMUIJ-UHFFFAOYSA-N
• XLogP: 14.55
• TPSA: 329.32 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 20
• Rotatable Bonds: 14
• Heavy Atoms: 156
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2220.14
LogP ≤ 5	14.55
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide?

The IUPAC name of N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide (CID 158000426) is N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide.

What is the SMILES notation for N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide?

The canonical SMILES for N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide is CC(C)(C)N1CCC(NC(=O)N2CC3COCC3C2)CC1.CC(C)(C)N1CCC(NC(=O)N2CCC(F)(F)CC2)CC1.CC(C)(C)N1CCC(NC(=O)N2CCC(O)CC2)CC1.CC(C)N1CCC(NC(=O)C2CCOCC2)CC1.CC(C)N1CCC(NC(=O)N2CCCC(F)(F)C2)CC1.CC(C)N1CCC(NC(=O)N2CCCC(F)C2)CC1.CC(C)N1CCC(NC(=O)N2CCOCC2)CC1.CC1CCN(C(=O)NC2CCN(C(C)C)CC2)CC1.

What is the InChIKey of N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide?

The InChIKey is FDQYPQVXRFMUIJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H29N3O2.C15H27F2N3O.C15H29N3O2.C15H29N3O.C14H25F2N3O.C14H26FN3O.C14H26N2O2.C13H25N3O2/c1-16(2,3)19-6-4-14(5-7-19)17-15(20)18-8-12-10-21-11-13(12)9-18;1-14(2,3)20-8-4-12(5-9-20)18-13(21)19-10-6-15(16,17)7-11-19;1-15(2,3)18-10-4-12(5-11-18)16-14(20)17-8-6-13(19)7-9-17;1-12(2)17-10-6-14(7-11-17)16-15(19)18-8-4-13(3)5-9-18;1-11(2)18-8-4-12(5-9-18)17-13(20)19-7-3-6-14(15,16)10-19;1-11(2)17-8-5-13(6-9-17)16-14(19)18-7-3-4-12(15)10-18;1-11(2)16-7-3-13(4-8-16)15-14(17)12-5-9-18-10-6-12;1-11(2)15-5-3-12(4-6-15)14-13(17)16-7-9-18-10-8-16/h12-14H,4-11H2,1-3H3,(H,17,20);12H,4-11H2,1-3H3,(H,18,21);12-13,19H,4-11H2,1-3H3,(H,16,20);12-14H,4-11H2,1-3H3,(H,16,19);11-12H,3-10H2,1-2H3,(H,17,20);11-13H,3-10H2,1-2H3,(H,16,19);11-13H,3-10H2,1-2H3,(H,15,17);11-12H,3-10H2,1-2H3,(H,14,17).

What are the key properties of N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide?

N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide has a molecular weight of 2220.14 g/mol, XLogP of 14.55, 14 rotatable bonds, 9 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for N-(1-tert-butylpiperidin-4-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]pyrrole-5-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4,4-difluoropiperidine-1-carboxamide;N-(1-tert-butylpiperidin-4-yl)-4-hydroxypiperidine-1-carboxamide;3,3-difluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;3-fluoro-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;4-methyl-N-(1-propan-2-ylpiperidin-4-yl)piperidine-1-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)morpholine-4-carboxamide;N-(1-propan-2-ylpiperidin-4-yl)oxane-4-carboxamide is sourced from PubChem (CID 158000426), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).