1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone

C118H95FN24O8S6 — CID 158000541

About 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone

1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone (PubChem CID 158000541) has the molecular formula C118H95FN24O8S6 and a molecular weight of 2188.62 g/mol. Its IUPAC name is 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone.

Molecular Properties

• Compound Name: 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone
• PubChem CID: 158000541
• Molecular Formula: C118H95FN24O8S6
• Molecular Weight: 2188.62 g/mol
• Exact Mass: 2186.61
• IUPAC Name: 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone
• SMILES: COc1cnc(-c2cc(C(=O)Cc3nc(C)cs3)c3nccn3c2)cn1.Cc1cc(-c2cc(C(=O)Cc3nc(C)cs3)c3nccn3c2)ccn1.Cc1cccc(-c2cc(C(=O)Cc3nc(C)cs3)c3nccn3c2)c1.Cc1csc(CC(=O)c2cc(-c3ccc4occc4c3)cn3ccnc23)n1.Cc1csc(CC(=O)c2cc(-c3cccc4c3cnn4C)cn3ccnc23)n1.Cc1csc(CC(=O)c2cc(-c3cnc(F)c(C)c3)cn3ccnc23)n1
• InChI: InChI=1S/C21H17N5OS.C21H15N3O2S.C20H17N3OS.C19H15FN4OS.C19H16N4OS.C18H15N5O2S/c1-13-12-28-20(24-13)9-19(27)16-8-14(11-26-7-6-22-21(16)26)15-4-3-5-18-17(15)10-23-25(18)2;1-13-12-27-20(23-13)10-18(25)17-9-16(11-24-6-5-22-21(17)24)14-2-3-19-15(8-14)4-7-26-19;1-13-4-3-5-15(8-13)16-9-17(20-21-6-7-23(20)11-16)18(24)10-19-22-14(2)12-25-19;1-11-5-13(8-22-18(11)20)14-6-15(19-21-3-4-24(19)9-14)16(25)7-17-23-12(2)10-26-17;1-12-7-14(3-4-20-12)15-8-16(19-21-5-6-23(19)10-15)17(24)9-18-22-13(2)11-25-18;1-11-10-26-17(22-11)6-15(24)13-5-12(9-23-4-3-19-18(13)23)14-7-21-16(25-2)8-20-14/h3-8,10-12H,9H2,1-2H3;2-9,11-12H,10H2,1H3;3-9,11-12H,10H2,1-2H3;3-6,8-10H,7H2,1-2H3;3-8,10-11H,9H2,1-2H3;3-5,7-10H,6H2,1-2H3
• InChIKey: FDRGYFNTOOCHIT-UHFFFAOYSA-N
• XLogP: 24.44
• TPSA: 375.31 Ų
• H-Bond Acceptors: 38
• Rotatable Bonds: 25
• Heavy Atoms: 157
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2188.62
LogP ≤ 5	24.44
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	38

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone?

The IUPAC name of 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone (CID 158000541) is 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone.

What is the SMILES notation for 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone?

The canonical SMILES for 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone is COc1cnc(-c2cc(C(=O)Cc3nc(C)cs3)c3nccn3c2)cn1.Cc1cc(-c2cc(C(=O)Cc3nc(C)cs3)c3nccn3c2)ccn1.Cc1cccc(-c2cc(C(=O)Cc3nc(C)cs3)c3nccn3c2)c1.Cc1csc(CC(=O)c2cc(-c3ccc4occc4c3)cn3ccnc23)n1.Cc1csc(CC(=O)c2cc(-c3cccc4c3cnn4C)cn3ccnc23)n1.Cc1csc(CC(=O)c2cc(-c3cnc(F)c(C)c3)cn3ccnc23)n1.

What is the InChIKey of 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone?

The InChIKey is FDRGYFNTOOCHIT-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H17N5OS.C21H15N3O2S.C20H17N3OS.C19H15FN4OS.C19H16N4OS.C18H15N5O2S/c1-13-12-28-20(24-13)9-19(27)16-8-14(11-26-7-6-22-21(16)26)15-4-3-5-18-17(15)10-23-25(18)2;1-13-12-27-20(23-13)10-18(25)17-9-16(11-24-6-5-22-21(17)24)14-2-3-19-15(8-14)4-7-26-19;1-13-4-3-5-15(8-13)16-9-17(20-21-6-7-23(20)11-16)18(24)10-19-22-14(2)12-25-19;1-11-5-13(8-22-18(11)20)14-6-15(19-21-3-4-24(19)9-14)16(25)7-17-23-12(2)10-26-17;1-12-7-14(3-4-20-12)15-8-16(19-21-5-6-23(19)10-15)17(24)9-18-22-13(2)11-25-18;1-11-10-26-17(22-11)6-15(24)13-5-12(9-23-4-3-19-18(13)23)14-7-21-16(25-2)8-20-14/h3-8,10-12H,9H2,1-2H3;2-9,11-12H,10H2,1H3;3-9,11-12H,10H2,1-2H3;3-6,8-10H,7H2,1-2H3;3-8,10-11H,9H2,1-2H3;3-5,7-10H,6H2,1-2H3.

What are the key properties of 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone?

1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone has a molecular weight of 2188.62 g/mol, XLogP of 24.44, 25 rotatable bonds, 0 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[6-(1-benzofuran-5-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(6-fluoro-5-methyl-3-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(5-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(1-methylindazol-4-yl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(3-methylphenyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone;1-[6-(2-methyl-4-pyridinyl)imidazo[1,2-a]pyridin-8-yl]-2-(4-methyl-1,3-thiazol-2-yl)ethanone is sourced from PubChem (CID 158000541), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).