2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide

C309H319F20N73O38 — CID 158004114

About 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide

2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide (PubChem CID 158004114) has the molecular formula C309H319F20N73O38 and a molecular weight of 6043.38 g/mol. Its IUPAC name is 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide
• PubChem CID: 158004114
• Molecular Formula: C309H319F20N73O38
• Molecular Weight: 6043.38 g/mol
• Exact Mass: 6039.50
• IUPAC Name: 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide
• SMILES: CCNC(=O)c1cc(-c2cc(C)c3c(n2)C(C)(C)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1C.CCOc1cc(-c2cc(C)c3c(n2)CN(c2ccn([C@H]4CCOC4)n2)C3=O)cnc1C.CCOc1cc(-c2cc(C)c3c(n2)CN(c2cnn(CC)c2)C3=O)cnc1OC.CCn1cc(N2Cc3nc(-c4cnc(OC)c(OC(C)C)c4)cc(C)c3C2=O)cn1.CCn1cc(N2Cc3nc(-c4cnc(OCCOC)c(OC)c4)cc(C)c3C2=O)cn1.COc1cc(-c2cc(C)c3c(n2)C(C)(C)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1F.COc1cncc(-c2cc(C)c3c(n2)C(C)(C)N(c2ccn(C[C@H](C)O)n2)C3=O)c1.COc1cncc(-c2cc(C)c3c(n2)CN(c2ccn(C4COC4)n2)C3=O)c1.COc1cncc(-c2cc(C)c3c(n2)CN(c2ccn(C[C@@H](C)F)n2)C3=O)c1.COc1cncc(-c2cc(C)c3c(n2)CN(c2ccn([C@H]4CCOC4)n2)C3=O)c1.Cc1cc(-c2cnc(C)c(C(=O)NC(C)C)c2)nc2c1C(=O)N(c1cnn(CC(F)(F)F)c1)C2(C)C.Cc1cc(-c2cnc(C)c(OCC(F)F)c2)nc2c1C(=O)N(c1ccn([C@H]3CCOC3)n1)C2.Cc1cc(-c2cncc(C(=O)NCC(F)F)c2)nc2c1C(=O)N(c1cnn(CC(F)(F)F)c1)C2(C)C.Cc1cc(-c2cncc(OCC(F)F)c2)nc2c1C(=O)N(c1ccn([C@H]3CCOC3)n1)C2
• InChI: InChI=1S/C25H27F3N6O2.C24H25F3N6O2.C23H21F5N6O2.C23H23F2N5O3.C23H25N5O3.C22H21F2N5O3.C22H25N5O4.2C22H25N5O3.C21H19F4N5O2.C21H21N5O3.C21H23N5O3.C20H20FN5O2.C20H19N5O3/c1-13(2)31-22(35)18-8-16(9-29-15(18)4)19-7-14(3)20-21(32-19)24(5,6)34(23(20)36)17-10-30-33(11-17)12-25(26,27)28;1-6-28-21(34)17-8-15(9-29-14(17)3)18-7-13(2)19-20(31-18)23(4,5)33(22(19)35)16-10-30-32(11-16)12-24(25,26)27;1-12-4-16(13-5-14(7-29-6-13)20(35)30-9-17(24)25)32-19-18(12)21(36)34(22(19,2)3)15-8-31-33(10-15)11-23(26,27)28;1-13-7-17(15-8-19(14(2)26-9-15)33-12-20(24)25)27-18-10-29(23(31)22(13)18)21-3-5-30(28-21)16-4-6-32-11-16;1-4-31-20-10-16(11-24-15(20)3)18-9-14(2)22-19(25-18)12-27(23(22)29)21-5-7-28(26-21)17-6-8-30-13-17;1-13-6-17(14-7-16(9-25-8-14)32-12-19(23)24)26-18-10-28(22(30)21(13)18)20-2-4-29(27-20)15-3-5-31-11-15;1-5-26-12-16(11-24-26)27-13-18-20(22(27)28)14(2)8-17(25-18)15-9-19(30-4)21(23-10-15)31-7-6-29-3;1-13-8-17(15-9-16(30-5)11-23-10-15)24-20-19(13)21(29)27(22(20,3)4)18-6-7-26(25-18)12-14(2)28;1-6-26-11-16(10-24-26)27-12-18-20(22(27)28)14(4)7-17(25-18)15-8-19(30-13(2)3)21(29-5)23-9-15;1-11-5-14(12-6-15(32-4)18(22)26-7-12)28-17-16(11)19(31)30(20(17,2)3)13-8-27-29(9-13)10-21(23,24)25;1-13-7-17(14-8-16(28-2)10-22-9-14)23-18-11-25(21(27)20(13)18)19-3-5-26(24-19)15-4-6-29-12-15;1-5-25-11-15(10-23-25)26-12-17-19(21(26)27)13(3)7-16(24-17)14-8-18(29-6-2)20(28-4)22-9-14;1-12-6-16(14-7-15(28-3)9-22-8-14)23-17-11-26(20(27)19(12)17)18-4-5-25(24-18)10-13(2)21;1-12-5-16(13-6-15(27-2)8-21-7-13)22-17-9-24(20(26)19(12)17)18-3-4-25(23-18)14-10-28-11-14/h7-11,13H,12H2,1-6H3,(H,31,35);7-11H,6,12H2,1-5H3,(H,28,34);4-8,10,17H,9,11H2,1-3H3,(H,30,35);3,5,7-9,16,20H,4,6,10-12H2,1-2H3;5,7,9-11,17H,4,6,8,12-13H2,1-3H3;2,4,6-9,15,19H,3,5,10-12H2,1H3;8-12H,5-7,13H2,1-4H3;6-11,14,28H,12H2,1-5H3;7-11,13H,6,12H2,1-5H3;5-9H,10H2,1-4H3;3,5,7-10,15H,4,6,11-12H2,1-2H3;7-11H,5-6,12H2,1-4H3;4-9,13H,10-11H2,1-3H3;3-8,14H,9-11H2,1-2H3/t;;;16-;17-;15-;;14-;;;15-;;13-;/m...000.0..0.1./s1
• InChIKey: FEBRQJWZNBESQI-JRHMNWJOSA-N
• XLogP: 48.69
• TPSA: 1186.87 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 94
• Rotatable Bonds: 75
• Heavy Atoms: 440
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	6043.38
LogP ≤ 5	48.69
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	94

Frequently Asked Questions

What is the IUPAC name of 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide?

The IUPAC name of 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide (CID 158004114) is 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide.

What is the SMILES notation for 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide?

The canonical SMILES for 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide is CCNC(=O)c1cc(-c2cc(C)c3c(n2)C(C)(C)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1C.CCOc1cc(-c2cc(C)c3c(n2)CN(c2ccn([C@H]4CCOC4)n2)C3=O)cnc1C.CCOc1cc(-c2cc(C)c3c(n2)CN(c2cnn(CC)c2)C3=O)cnc1OC.CCn1cc(N2Cc3nc(-c4cnc(OC)c(OC(C)C)c4)cc(C)c3C2=O)cn1.CCn1cc(N2Cc3nc(-c4cnc(OCCOC)c(OC)c4)cc(C)c3C2=O)cn1.COc1cc(-c2cc(C)c3c(n2)C(C)(C)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1F.COc1cncc(-c2cc(C)c3c(n2)C(C)(C)N(c2ccn(C[C@H](C)O)n2)C3=O)c1.COc1cncc(-c2cc(C)c3c(n2)CN(c2ccn(C4COC4)n2)C3=O)c1.COc1cncc(-c2cc(C)c3c(n2)CN(c2ccn(C[C@@H](C)F)n2)C3=O)c1.COc1cncc(-c2cc(C)c3c(n2)CN(c2ccn([C@H]4CCOC4)n2)C3=O)c1.Cc1cc(-c2cnc(C)c(C(=O)NC(C)C)c2)nc2c1C(=O)N(c1cnn(CC(F)(F)F)c1)C2(C)C.Cc1cc(-c2cnc(C)c(OCC(F)F)c2)nc2c1C(=O)N(c1ccn([C@H]3CCOC3)n1)C2.Cc1cc(-c2cncc(C(=O)NCC(F)F)c2)nc2c1C(=O)N(c1cnn(CC(F)(F)F)c1)C2(C)C.Cc1cc(-c2cncc(OCC(F)F)c2)nc2c1C(=O)N(c1ccn([C@H]3CCOC3)n1)C2.

What is the InChIKey of 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide?

The InChIKey is FEBRQJWZNBESQI-JRHMNWJOSA-N. The full InChI is InChI=1S/C25H27F3N6O2.C24H25F3N6O2.C23H21F5N6O2.C23H23F2N5O3.C23H25N5O3.C22H21F2N5O3.C22H25N5O4.2C22H25N5O3.C21H19F4N5O2.C21H21N5O3.C21H23N5O3.C20H20FN5O2.C20H19N5O3/c1-13(2)31-22(35)18-8-16(9-29-15(18)4)19-7-14(3)20-21(32-19)24(5,6)34(23(20)36)17-10-30-33(11-17)12-25(26,27)28;1-6-28-21(34)17-8-15(9-29-14(17)3)18-7-13(2)19-20(31-18)23(4,5)33(22(19)35)16-10-30-32(11-16)12-24(25,26)27;1-12-4-16(13-5-14(7-29-6-13)20(35)30-9-17(24)25)32-19-18(12)21(36)34(22(19,2)3)15-8-31-33(10-15)11-23(26,27)28;1-13-7-17(15-8-19(14(2)26-9-15)33-12-20(24)25)27-18-10-29(23(31)22(13)18)21-3-5-30(28-21)16-4-6-32-11-16;1-4-31-20-10-16(11-24-15(20)3)18-9-14(2)22-19(25-18)12-27(23(22)29)21-5-7-28(26-21)17-6-8-30-13-17;1-13-6-17(14-7-16(9-25-8-14)32-12-19(23)24)26-18-10-28(22(30)21(13)18)20-2-4-29(27-20)15-3-5-31-11-15;1-5-26-12-16(11-24-26)27-13-18-20(22(27)28)14(2)8-17(25-18)15-9-19(30-4)21(23-10-15)31-7-6-29-3;1-13-8-17(15-9-16(30-5)11-23-10-15)24-20-19(13)21(29)27(22(20,3)4)18-6-7-26(25-18)12-14(2)28;1-6-26-11-16(10-24-26)27-12-18-20(22(27)28)14(4)7-17(25-18)15-8-19(30-13(2)3)21(29-5)23-9-15;1-11-5-14(12-6-15(32-4)18(22)26-7-12)28-17-16(11)19(31)30(20(17,2)3)13-8-27-29(9-13)10-21(23,24)25;1-13-7-17(14-8-16(28-2)10-22-9-14)23-18-11-25(21(27)20(13)18)19-3-5-26(24-19)15-4-6-29-12-15;1-5-25-11-15(10-23-25)26-12-17-19(21(26)27)13(3)7-16(24-17)14-8-18(29-6-2)20(28-4)22-9-14;1-12-6-16(14-7-15(28-3)9-22-8-14)23-17-11-26(20(27)19(12)17)18-4-5-25(24-18)10-13(2)21;1-12-5-16(13-6-15(27-2)8-21-7-13)22-17-9-24(20(26)19(12)17)18-3-4-25(23-18)14-10-28-11-14/h7-11,13H,12H2,1-6H3,(H,31,35);7-11H,6,12H2,1-5H3,(H,28,34);4-8,10,17H,9,11H2,1-3H3,(H,30,35);3,5,7-9,16,20H,4,6,10-12H2,1-2H3;5,7,9-11,17H,4,6,8,12-13H2,1-3H3;2,4,6-9,15,19H,3,5,10-12H2,1H3;8-12H,5-7,13H2,1-4H3;6-11,14,28H,12H2,1-5H3;7-11,13H,6,12H2,1-5H3;5-9H,10H2,1-4H3;3,5,7-10,15H,4,6,11-12H2,1-2H3;7-11H,5-6,12H2,1-4H3;4-9,13H,10-11H2,1-3H3;3-8,14H,9-11H2,1-2H3/t;;;16-;17-;15-;;14-;;;15-;;13-;/m...000.0..0.1./s1.

What are the key properties of 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide?

2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide has a molecular weight of 6043.38 g/mol, XLogP of 48.69, 75 rotatable bonds, 4 hydrogen bond donors, and 94 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[5-(2,2-difluoroethoxy)-6-methyl-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-[5-(2,2-difluoroethoxy)-3-pyridinyl]-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-(2,2-difluoroethyl)-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;2-(5-ethoxy-6-methoxy-3-pyridinyl)-6-(1-ethylpyrazol-4-yl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-ethoxy-6-methyl-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;N-ethyl-2-methyl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide;6-(1-ethylpyrazol-4-yl)-2-[5-methoxy-6-(2-methoxyethoxy)-3-pyridinyl]-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-(1-ethylpyrazol-4-yl)-2-(6-methoxy-5-propan-2-yloxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;2-(6-fluoro-5-methoxy-3-pyridinyl)-4,7,7-trimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2R)-2-fluoropropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4-methyl-7H-pyrrolo[3,4-b]pyridin-5-one;6-[1-[(2S)-2-hydroxypropyl]pyrazol-3-yl]-2-(5-methoxy-3-pyridinyl)-4,7,7-trimethylpyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-(oxetan-3-yl)pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-(5-methoxy-3-pyridinyl)-4-methyl-6-[1-[(3S)-oxolan-3-yl]pyrazol-3-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;2-methyl-N-propan-2-yl-5-[4,7,7-trimethyl-5-oxo-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-2-yl]pyridine-3-carboxamide is sourced from PubChem (CID 158004114), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).