N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine

C94H97N35O2S — CID 158005274

About N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine

N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine (PubChem CID 158005274) has the molecular formula C94H97N35O2S and a molecular weight of 1781.12 g/mol. Its IUPAC name is N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

• Compound Name: N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine
• PubChem CID: 158005274
• Molecular Formula: C94H97N35O2S
• Molecular Weight: 1781.12 g/mol
• Exact Mass: 1779.83
• IUPAC Name: N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine
• SMILES: CC(C)Oc1cccc(Nc2nccn3c(-c4cnn(C)c4)cnc23)c1.Cn1cc(-c2cnc3c(Nc4ccc5c(c4)CNCC5)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc5c(c4)NCCC5)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccc(OC5CCNC5)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc(C5CCCN5)cs4)nccn23)cn1
• InChI: InChI=1S/C20H21N7O.2C19H19N7.C19H20N6O.C17H18N8S/c1-26-13-14(10-24-26)18-12-23-20-19(22-7-8-27(18)20)25-15-3-2-4-16(9-15)28-17-5-6-21-11-17;1-25-12-15(10-23-25)17-11-22-19-18(21-6-7-26(17)19)24-16-3-2-13-4-5-20-9-14(13)8-16;1-25-12-14(10-23-25)17-11-22-19-18(21-7-8-26(17)19)24-15-5-4-13-3-2-6-20-16(13)9-15;1-13(2)26-16-6-4-5-15(9-16)23-18-19-21-11-17(25(19)8-7-20-18)14-10-22-24(3)12-14;1-24-9-11(7-21-24)14-8-20-16-15(19-5-6-25(14)16)23-17-22-13(10-26-17)12-3-2-4-18-12/h2-4,7-10,12-13,17,21H,5-6,11H2,1H3,(H,22,25);2-3,6-8,10-12,20H,4-5,9H2,1H3,(H,21,24);4-5,7-12,20H,2-3,6H2,1H3,(H,21,24);4-13H,1-3H3,(H,20,23);5-10,12,18H,2-4H2,1H3,(H,19,22,23)
• InChIKey: FEFGZFFBQWQNJE-UHFFFAOYSA-N
• XLogP: 14.78
• TPSA: 379.67 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 38
• Rotatable Bonds: 20
• Heavy Atoms: 132
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1781.12
LogP ≤ 5	14.78
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	38

Frequently Asked Questions

What is the IUPAC name of N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine?

The IUPAC name of N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine (CID 158005274) is N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine.

What is the SMILES notation for N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine?

The canonical SMILES for N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine is CC(C)Oc1cccc(Nc2nccn3c(-c4cnn(C)c4)cnc23)c1.Cn1cc(-c2cnc3c(Nc4ccc5c(c4)CNCC5)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc5c(c4)NCCC5)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccc(OC5CCNC5)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4nc(C5CCCN5)cs4)nccn23)cn1.

What is the InChIKey of N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine?

The InChIKey is FEFGZFFBQWQNJE-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H21N7O.2C19H19N7.C19H20N6O.C17H18N8S/c1-26-13-14(10-24-26)18-12-23-20-19(22-7-8-27(18)20)25-15-3-2-4-16(9-15)28-17-5-6-21-11-17;1-25-12-15(10-23-25)17-11-22-19-18(21-6-7-26(17)19)24-16-3-2-13-4-5-20-9-14(13)8-16;1-25-12-14(10-23-25)17-11-22-19-18(21-7-8-26(17)19)24-15-5-4-13-3-2-6-20-16(13)9-15;1-13(2)26-16-6-4-5-15(9-16)23-18-19-21-11-17(25(19)8-7-20-18)14-10-22-24(3)12-14;1-24-9-11(7-21-24)14-8-20-16-15(19-5-6-25(14)16)23-17-22-13(10-26-17)12-3-2-4-18-12/h2-4,7-10,12-13,17,21H,5-6,11H2,1H3,(H,22,25);2-3,6-8,10-12,20H,4-5,9H2,1H3,(H,21,24);4-5,7-12,20H,2-3,6H2,1H3,(H,21,24);4-13H,1-3H3,(H,20,23);5-10,12,18H,2-4H2,1H3,(H,19,22,23).

What are the key properties of N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine?

N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 1781.12 g/mol, XLogP of 14.78, 20 rotatable bonds, 9 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-4-pyrrolidin-2-yl-1,3-thiazol-2-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroisoquinolin-7-amine;N-[3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-1,2,3,4-tetrahydroquinolin-7-amine;3-(1-methylpyrazol-4-yl)-N-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-3-yloxyphenyl)imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 158005274), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).