5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine

C164H154N56O8 — CID 158007432

IUPAC5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine
SMILESCC1=NCC(c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)=C1.CCn1nc(C)cc1-c1nc(C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)no1.Cc1[nH]ncc1-c1nc(C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)no1.Cc1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)n(C)n1.Cn1ncc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)c1N.Nc1ncc(-c2ccc(C3(c4noc(-c5cccnn5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5ccnnc5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5cncnc5)n4)CCC3)cc2)cn1
InChIInChI=1S/C22H23N7O.C21H21N7O.C21H20N6O.C20H20N8O.C20H19N7O.3C20H17N7O/c1-3-29-18(11-14(2)27-29)19-26-20(28-30-19)22(9-4-10-22)17-7-5-15(6-8-17)16-12-24-21(23)25-13-16;1-13-10-17(28(2)26-13)18-25-19(27-29-18)21(8-3-9-21)16-6-4-14(5-7-16)15-11-23-20(22)24-12-15;1-13-9-15(10-23-13)18-26-19(27-28-18)21(7-2-8-21)17-5-3-14(4-6-17)16-11-24-20(22)25-12-16;1-28-16(21)15(11-25-28)17-26-18(27-29-17)20(7-2-8-20)14-5-3-12(4-6-14)13-9-23-19(22)24-10-13;1-12-16(11-24-26-12)17-25-18(27-28-17)20(7-2-8-20)15-5-3-13(4-6-15)14-9-22-19(21)23-10-14;21-19-22-10-15(11-23-19)13-2-4-16(5-3-13)20(7-1-8-20)18-26-17(28-27-18)14-6-9-24-25-12-14;21-19-24-10-14(11-25-19)13-2-4-16(5-3-13)20(6-1-7-20)18-26-17(28-27-18)15-8-22-12-23-9-15;21-19-22-11-14(12-23-19)13-4-6-15(7-5-13)20(8-2-9-20)18-25-17(28-27-18)16-3-1-10-24-26-16/h5-8,11-13H,3-4,9-10H2,1-2H3,(H2,23,24,25);4-7,10-12H,3,8-9H2,1-2H3,(H2,22,23,24);3-6,9,11-12H,2,7-8,10H2,1H3,(H2,22,24,25);3-6,9-11H,2,7-8,21H2,1H3,(H2,22,23,24);3-6,9-11H,2,7-8H2,1H3,(H,24,26)(H2,21,22,23);2-6,9-12H,1,7-8H2,(H2,21,22,23);2-5,8-12H,1,6-7H2,(H2,21,24,25);1,3-7,10-12H,2,8-9H2,(H2,21,22,23)
InChIKeyFELTYADCOAPJGX-UHFFFAOYSA-N
MW3037.42 g/mol
LogP25.44
Rot. Bonds33

About 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine

5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine (PubChem CID 158007432) has the molecular formula C164H154N56O8 and a molecular weight of 3037.42 g/mol. Its IUPAC name is 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine.

Molecular Properties

Compound Name5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine
PubChem CID158007432
Molecular FormulaC164H154N56O8
Molecular Weight3037.42 g/mol
Exact Mass3035.34
IUPAC Name5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine
SMILESCC1=NCC(c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)=C1.CCn1nc(C)cc1-c1nc(C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)no1.Cc1[nH]ncc1-c1nc(C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)no1.Cc1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)n(C)n1.Cn1ncc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)c1N.Nc1ncc(-c2ccc(C3(c4noc(-c5cccnn5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5ccnnc5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5cncnc5)n4)CCC3)cc2)cn1
InChIInChI=1S/C22H23N7O.C21H21N7O.C21H20N6O.C20H20N8O.C20H19N7O.3C20H17N7O/c1-3-29-18(11-14(2)27-29)19-26-20(28-30-19)22(9-4-10-22)17-7-5-15(6-8-17)16-12-24-21(23)25-13-16;1-13-10-17(28(2)26-13)18-25-19(27-29-18)21(8-3-9-21)16-6-4-14(5-7-16)15-11-23-20(22)24-12-15;1-13-9-15(10-23-13)18-26-19(27-28-18)21(7-2-8-21)17-5-3-14(4-6-17)16-11-24-20(22)25-12-16;1-28-16(21)15(11-25-28)17-26-18(27-29-17)20(7-2-8-20)14-5-3-12(4-6-14)13-9-23-19(22)24-10-13;1-12-16(11-24-26-12)17-25-18(27-28-17)20(7-2-8-20)15-5-3-13(4-6-15)14-9-22-19(21)23-10-14;21-19-22-10-15(11-23-19)13-2-4-16(5-3-13)20(7-1-8-20)18-26-17(28-27-18)14-6-9-24-25-12-14;21-19-24-10-14(11-25-19)13-2-4-16(5-3-13)20(6-1-7-20)18-26-17(28-27-18)15-8-22-12-23-9-15;21-19-22-11-14(12-23-19)13-4-6-15(7-5-13)20(8-2-9-20)18-25-17(28-27-18)16-3-1-10-24-26-16/h5-8,11-13H,3-4,9-10H2,1-2H3,(H2,23,24,25);4-7,10-12H,3,8-9H2,1-2H3,(H2,22,23,24);3-6,9,11-12H,2,7-8,10H2,1H3,(H2,22,24,25);3-6,9-11H,2,7-8,21H2,1H3,(H2,22,23,24);3-6,9-11H,2,7-8H2,1H3,(H,24,26)(H2,21,22,23);2-6,9-12H,1,7-8H2,(H2,21,22,23);2-5,8-12H,1,6-7H2,(H2,21,24,25);1,3-7,10-12H,2,8-9H2,(H2,21,22,23)
InChIKeyFELTYADCOAPJGX-UHFFFAOYSA-N
XLogP25.44
TPSA923.62 Ų
H-Bond Donors10
H-Bond Acceptors63
Rotatable Bonds33
Heavy Atoms228
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003037.42
LogP ≤ 525.44
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1063

Analyze 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine with MolForge

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Related Compounds

4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-N-methylpyrazole-1-carboxamide;2-[[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]-methylamino]ethanol;[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]-(4,4-difluoropiperidin-1-yl)methanone;[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]-(3-hydroxypyrrolidin-1-yl)methanone;5-[4-[1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine
CID 160781072
bis(2-[4-[3-[(1R)-1-[4-(2-aminopyrimidin-5-yl)phenyl]-1-cyclopropylethyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide);5-[4-[1-cyclopropyl-1-[5-(1-methylimidazol-4-yl)-1,2,4-oxadiazol-3-yl]ethyl]phenyl]pyrimidin-2-amine;5-[4-[1-cyclopropyl-1-[5-(2-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]ethyl]phenyl]pyrimidin-2-amine
CID 157313971
1-[2-[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]ethyl]pyrrolidin-2-one;2-[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N-(2-methylpropyl)acetamide;5-[4-[1-[5-[5-(2-methoxyethylamino)pyrazin-2-yl]-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyridin-2-amine;5-[4-[1-[5-(5-propylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine
CID 157347242
1-[4-[3-[(1S)-1-[6-(6-amino-3-pyridinyl)-3-pyridinyl]-1-cyclopropylethyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-2-methylpropan-2-ol;1-[[6-[3-[2-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]pyridazin-3-yl]amino]-2-methylpropan-2-ol;5-[5-[(1S)-1-cyclopropyl-1-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]ethyl]-2-pyridinyl]pyridin-2-amine;5-[5-[2-[5-[1-[2-(2-methoxyethoxy)ethyl]pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[(2R)-3-methyl-2-[5-[1-(oxetan-3-yl)pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]butan-2-yl]-2-pyridinyl]pyrimidin-2-amine
CID 157494846
1-[4-[3-[2-[4-(2-aminopyrimidin-5-yl)phenyl]propan-2-yl]-1,2,4-oxadiazol-5-yl]anilino]-2-methylpropan-2-ol;5-[4-[2-[5-[4-(dimethylamino)piperidin-1-yl]-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]phenyl]pyrimidin-2-amine;5-[4-[3-methyl-2-[5-[4-(methylamino)piperidin-1-yl]-1,2,4-oxadiazol-3-yl]butan-2-yl]phenyl]pyrimidin-2-amine;5-[4-[2-[5-(1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]phenyl]pyrimidin-2-amine;5-[4-[2-[5-(1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]phenyl]pyrimidin-2-amine
CID 157516883
2-[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N-methyl-N-(oxan-3-yl)acetamide;2-[[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]amino]ethanol;2-[[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]-methylamino]ethanol;3-[1-[4-(2-cyclopropylpyrimidin-5-yl)phenyl]cyclobutyl]-5-(1-methylpyrazol-4-yl)-1,2,4-oxadiazole;5-[4-[1-[5-(1H-pyrazol-5-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine
CID 157734983
2-[4-[3-[(1R)-1-[4-(2-amino-6-oxo-1H-pyrimidin-5-yl)phenyl]-1-cyclopropylethyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N,N-dimethylacetamide;5-[4-[(1R)-1-cyclopropyl-1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]ethyl]phenyl]pyrimidin-2-amine;5-[4-[(1R)-1-cyclopropyl-1-[5-(1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]ethyl]phenyl]pyrimidin-2-amine;5-[4-[(1S)-1-cyclopropyl-1-[5-(1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]ethyl]phenyl]pyrimidin-2-amine
CID 157740998
6-[3-[2-[4-(2-aminopyrimidin-5-yl)phenyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]-1-methylpiperidin-2-one;6-[3-[2-[4-(2-aminopyrimidin-5-yl)phenyl]-3-methylbutan-2-yl]-1,2,4-oxadiazol-5-yl]piperidin-2-one;5-[4-[2-[5-(1,1-dioxo-1,4-thiazinan-4-yl)-1,2,4-oxadiazol-3-yl]-3-methylbutan-2-yl]phenyl]pyrimidin-2-amine;5-[4-[3-methyl-2-[5-(2-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]butan-2-yl]phenyl]pyrimidin-2-amine;5-[4-[3-methyl-2-[5-(1H-pyrazol-5-yl)-1,2,4-oxadiazol-3-yl]butan-2-yl]phenyl]pyrimidin-2-amine
CID 157859330
2-amino-5-[4-[1-[5-(1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyridine-3-carbonitrile;2-[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-1-[(3S)-3-methoxypyrrolidin-1-yl]ethanone;(3S)-1-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]pyrrolidin-3-ol;ethyl 3-[4-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]-2-pyridinyl]piperazin-1-yl]propanoate;methane
CID 157958879
3-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]benzonitrile;4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]benzonitrile;[(2S)-1-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]pyrrolidin-2-yl]methanol;[(2R)-1-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazin-2-yl]pyrrolidin-2-yl]methanol;methane;5-[4-[1-[5-(2H-triazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine
CID 157994792
1-[5-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]imidazol-1-yl]-2-methylpropan-2-ol;2-[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N-tert-butylacetamide;1-[4-[3-[1-[4-(2-aminopyrimidin-5-yl)phenyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-2-methylpropan-2-ol;5-[4-[1-(5-phenyl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine
CID 158107074
2-[4-[3-[1-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]acetonitrile;2-[4-[3-[1-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N-tert-butylacetamide;2-[4-[3-[1-[6-(2-aminopyrimidin-5-yl)-3-pyridinyl]cyclobutyl]-1,2,4-oxadiazol-5-yl]pyrazol-1-yl]-N-tert-butyl-N-methylacetamide;5-[5-[1-[5-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-1,2,4-oxadiazol-3-yl]cyclobutyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[1-[5-[5-(4-methylpiperazin-1-yl)pyrazin-2-yl]-1,2,4-oxadiazol-3-yl]cyclobutyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[1-[5-(4-piperazin-1-ylphenyl)-1,2,4-oxadiazol-3-yl]cyclobutyl]-2-pyridinyl]pyrimidin-2-amine;5-[5-[1-[5-(5-piperazin-1-ylpyrazin-2-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]-2-pyridinyl]pyrimidin-2-amine
CID 158167183

Frequently Asked Questions

What is the IUPAC name of 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?
The IUPAC name of 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine (CID 158007432) is 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine.
What is the SMILES notation for 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?
The canonical SMILES for 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine is CC1=NCC(c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)=C1.CCn1nc(C)cc1-c1nc(C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)no1.Cc1[nH]ncc1-c1nc(C2(c3ccc(-c4cnc(N)nc4)cc3)CCC2)no1.Cc1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)n(C)n1.Cn1ncc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)c1N.Nc1ncc(-c2ccc(C3(c4noc(-c5cccnn5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5ccnnc5)n4)CCC3)cc2)cn1.Nc1ncc(-c2ccc(C3(c4noc(-c5cncnc5)n4)CCC3)cc2)cn1.
What is the InChIKey of 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?
The InChIKey is FELTYADCOAPJGX-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H23N7O.C21H21N7O.C21H20N6O.C20H20N8O.C20H19N7O.3C20H17N7O/c1-3-29-18(11-14(2)27-29)19-26-20(28-30-19)22(9-4-10-22)17-7-5-15(6-8-17)16-12-24-21(23)25-13-16;1-13-10-17(28(2)26-13)18-25-19(27-29-18)21(8-3-9-21)16-6-4-14(5-7-16)15-11-23-20(22)24-12-15;1-13-9-15(10-23-13)18-26-19(27-28-18)21(7-2-8-21)17-5-3-14(4-6-17)16-11-24-20(22)25-12-16;1-28-16(21)15(11-25-28)17-26-18(27-29-17)20(7-2-8-20)14-5-3-12(4-6-14)13-9-23-19(22)24-10-13;1-12-16(11-24-26-12)17-25-18(27-28-17)20(7-2-8-20)15-5-3-13(4-6-15)14-9-22-19(21)23-10-14;21-19-22-10-15(11-23-19)13-2-4-16(5-3-13)20(7-1-8-20)18-26-17(28-27-18)14-6-9-24-25-12-14;21-19-24-10-14(11-25-19)13-2-4-16(5-3-13)20(6-1-7-20)18-26-17(28-27-18)15-8-22-12-23-9-15;21-19-22-11-14(12-23-19)13-4-6-15(7-5-13)20(8-2-9-20)18-25-17(28-27-18)16-3-1-10-24-26-16/h5-8,11-13H,3-4,9-10H2,1-2H3,(H2,23,24,25);4-7,10-12H,3,8-9H2,1-2H3,(H2,22,23,24);3-6,9,11-12H,2,7-8,10H2,1H3,(H2,22,24,25);3-6,9-11H,2,7-8,21H2,1H3,(H2,22,23,24);3-6,9-11H,2,7-8H2,1H3,(H,24,26)(H2,21,22,23);2-6,9-12H,1,7-8H2,(H2,21,22,23);2-5,8-12H,1,6-7H2,(H2,21,24,25);1,3-7,10-12H,2,8-9H2,(H2,21,22,23).
What are the key properties of 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine?
5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine has a molecular weight of 3037.42 g/mol, XLogP of 25.44, 33 rotatable bonds, 10 hydrogen bond donors, and 63 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[4-[1-[5-(5-amino-1-methylpyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2,5-dimethylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(2-ethyl-5-methylpyrazol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-[5-(5-methyl-2H-pyrrol-3-yl)-1,2,4-oxadiazol-3-yl]cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-3-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyridazin-4-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine;5-[4-[1-(5-pyrimidin-5-yl-1,2,4-oxadiazol-3-yl)cyclobutyl]phenyl]pyrimidin-2-amine is sourced from PubChem (CID 158007432), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).