2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone

C119H98F7N17O6S5 — CID 158009303

About 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone

2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone (PubChem CID 158009303) has the molecular formula C119H98F7N17O6S5 and a molecular weight of 2155.53 g/mol. Its IUPAC name is 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone.

Molecular Properties

• Compound Name: 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone
• PubChem CID: 158009303
• Molecular Formula: C119H98F7N17O6S5
• Molecular Weight: 2155.53 g/mol
• Exact Mass: 2153.64
• IUPAC Name: 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone
• SMILES: C=C(C)c1sc(-c2cccnc2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.CC(C)(O)c1sc(-c2cccnc2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.CCc1sc(-c2ccc(N)nc2)nc1-c1ccc(CC(=O)c2cccc(F)c2C)nc1.CCc1sc(-c2cccnc2)nc1-c1ccc(CC(=O)c2cccc(F)c2C)nc1.Cc1cccc(F)c1C(=O)Cc1ccc(-c2nc(-c3cnn(C)c3C)sc2C)cn1
• InChI: InChI=1S/C24H19F2N3O2S.C24H17F2N3OS.C24H21FN4OS.C24H20FN3OS.C23H21FN4OS/c1-24(2,31)22-16(11-19(32-22)15-5-4-10-27-12-15)14-8-9-20(28-13-14)29-23(30)21-17(25)6-3-7-18(21)26;1-14(2)23-17(11-20(31-23)16-5-4-10-27-12-16)15-8-9-21(28-13-15)29-24(30)22-18(25)6-3-7-19(22)26;1-3-21-23(29-24(31-21)16-8-10-22(26)28-13-16)15-7-9-17(27-12-15)11-20(30)18-5-4-6-19(25)14(18)2;1-3-22-23(28-24(30-22)17-6-5-11-26-13-17)16-9-10-18(27-14-16)12-21(29)19-7-4-8-20(25)15(19)2;1-13-6-5-7-19(24)21(13)20(29)10-17-9-8-16(11-25-17)22-15(3)30-23(27-22)18-12-26-28(4)14(18)2/h3-13,31H,1-2H3,(H,28,29,30);3-13H,1H2,2H3,(H,28,29,30);4-10,12-13H,3,11H2,1-2H3,(H2,26,28);4-11,13-14H,3,12H2,1-2H3;5-9,11-12H,10H2,1-4H3
• InChIKey: FERLMQGZUXANIB-UHFFFAOYSA-N
• XLogP: 28.15
• TPSA: 328.16 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 26
• Rotatable Bonds: 27
• Heavy Atoms: 154
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2155.53
LogP ≤ 5	28.15
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	26

Frequently Asked Questions

What is the IUPAC name of 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone?

The IUPAC name of 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone (CID 158009303) is 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone.

What is the SMILES notation for 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone?

The canonical SMILES for 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone is C=C(C)c1sc(-c2cccnc2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.CC(C)(O)c1sc(-c2cccnc2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.CCc1sc(-c2ccc(N)nc2)nc1-c1ccc(CC(=O)c2cccc(F)c2C)nc1.CCc1sc(-c2cccnc2)nc1-c1ccc(CC(=O)c2cccc(F)c2C)nc1.Cc1cccc(F)c1C(=O)Cc1ccc(-c2nc(-c3cnn(C)c3C)sc2C)cn1.

What is the InChIKey of 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone?

The InChIKey is FERLMQGZUXANIB-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H19F2N3O2S.C24H17F2N3OS.C24H21FN4OS.C24H20FN3OS.C23H21FN4OS/c1-24(2,31)22-16(11-19(32-22)15-5-4-10-27-12-15)14-8-9-20(28-13-14)29-23(30)21-17(25)6-3-7-18(21)26;1-14(2)23-17(11-20(31-23)16-5-4-10-27-12-16)15-8-9-21(28-13-15)29-24(30)22-18(25)6-3-7-19(22)26;1-3-21-23(29-24(31-21)16-8-10-22(26)28-13-16)15-7-9-17(27-12-15)11-20(30)18-5-4-6-19(25)14(18)2;1-3-22-23(28-24(30-22)17-6-5-11-26-13-17)16-9-10-18(27-14-16)12-21(29)19-7-4-8-20(25)15(19)2;1-13-6-5-7-19(24)21(13)20(29)10-17-9-8-16(11-25-17)22-15(3)30-23(27-22)18-12-26-28(4)14(18)2/h3-13,31H,1-2H3,(H,28,29,30);3-13H,1H2,2H3,(H,28,29,30);4-10,12-13H,3,11H2,1-2H3,(H2,26,28);4-11,13-14H,3,12H2,1-2H3;5-9,11-12H,10H2,1-4H3.

What are the key properties of 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone?

2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone has a molecular weight of 2155.53 g/mol, XLogP of 28.15, 27 rotatable bonds, 4 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[5-[2-(6-amino-3-pyridinyl)-5-ethyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone;2,6-difluoro-N-[5-[2-(2-hydroxypropan-2-yl)-5-pyridin-3-ylthiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[5-(2-prop-1-en-2-yl-5-pyridin-3-ylthiophen-3-yl)-2-pyridinyl]benzamide;2-[5-[2-(1,5-dimethylpyrazol-4-yl)-5-methyl-1,3-thiazol-4-yl]-2-pyridinyl]-1-(2-fluoro-6-methylphenyl)ethanone;2-[5-(5-ethyl-2-pyridin-3-yl-1,3-thiazol-4-yl)-2-pyridinyl]-1-(3-fluoro-2-methylphenyl)ethanone is sourced from PubChem (CID 158009303), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).