N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide

C178H155F21N30O18S — CID 158015490

IUPACN-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide
SMILESCc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2oc(=O)[nH]c2c1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)cc2[nH]c(=O)oc12.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2nccn2c(N2CCOCC2)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cn2ccnc2c(N2CCOCC2)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cn2ccnc2c(N2CCOC[C@H]2C)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2[nH]ccc2n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2sccc2n1
InChIInChI=1S/C26H24F3N5O2.2C26H22F3N3O4.3C25H22F3N5O2.C25H21F3N4O2S/c1-16-6-7-20(31-25(35)18-4-3-5-19(12-18)26(27,28)29)13-21(16)22-14-33-9-8-30-23(33)24(32-22)34-10-11-36-15-17(34)2;1-15-5-6-19(30-24(33)16-3-2-4-18(11-16)26(27,28)29)14-20(15)17-12-21-23(36-25(34)31-21)22(13-17)32-7-9-35-10-8-32;1-15-5-6-18(30-24(33)16-3-2-4-17(11-16)26(27,28)29)12-20(15)21-13-19(32-7-9-35-10-8-32)14-22-23(21)36-25(34)31-22;1-16-5-6-19(30-24(34)17-3-2-4-18(13-17)25(26,27)28)14-20(16)21-15-33-8-7-29-22(33)23(31-21)32-9-11-35-12-10-32;1-16-5-6-19(30-23(34)17-3-2-4-18(13-17)25(26,27)28)14-20(16)21-15-22-29-7-8-33(22)24(31-21)32-9-11-35-12-10-32;1-15-5-6-18(30-24(34)16-3-2-4-17(13-16)25(26,27)28)14-19(15)22-31-20-7-8-29-21(20)23(32-22)33-9-11-35-12-10-33;1-15-5-6-18(29-24(33)16-3-2-4-17(13-16)25(26,27)28)14-19(15)22-30-20-7-12-35-21(20)23(31-22)32-8-10-34-11-9-32/h3-9,12-14,17H,10-11,15H2,1-2H3,(H,31,35);2*2-6,11-14H,7-10H2,1H3,(H,30,33)(H,31,34);2*2-8,13-15H,9-12H2,1H3,(H,30,34);2-8,13-14,29H,9-12H2,1H3,(H,30,34);2-7,12-14H,8-11H2,1H3,(H,29,33)/t17-;;;;;;/m1....../s1
InChIKeyFFKIJGQALBMVMJ-MFGRGHSBSA-N
MW3433.41 g/mol
LogP36.05
Rot. Bonds28

About N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide

N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide (PubChem CID 158015490) has the molecular formula C178H155F21N30O18S and a molecular weight of 3433.41 g/mol. Its IUPAC name is N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide.

Molecular Properties

Compound NameN-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide
PubChem CID158015490
Molecular FormulaC178H155F21N30O18S
Molecular Weight3433.41 g/mol
Exact Mass3431.15
IUPAC NameN-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide
SMILESCc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2oc(=O)[nH]c2c1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)cc2[nH]c(=O)oc12.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2nccn2c(N2CCOCC2)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cn2ccnc2c(N2CCOCC2)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cn2ccnc2c(N2CCOC[C@H]2C)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2[nH]ccc2n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2sccc2n1
InChIInChI=1S/C26H24F3N5O2.2C26H22F3N3O4.3C25H22F3N5O2.C25H21F3N4O2S/c1-16-6-7-20(31-25(35)18-4-3-5-19(12-18)26(27,28)29)13-21(16)22-14-33-9-8-30-23(33)24(32-22)34-10-11-36-15-17(34)2;1-15-5-6-19(30-24(33)16-3-2-4-18(11-16)26(27,28)29)14-20(15)17-12-21-23(36-25(34)31-21)22(13-17)32-7-9-35-10-8-32;1-15-5-6-18(30-24(33)16-3-2-4-17(11-16)26(27,28)29)12-20(15)21-13-19(32-7-9-35-10-8-32)14-22-23(21)36-25(34)31-22;1-16-5-6-19(30-24(34)17-3-2-4-18(13-17)25(26,27)28)14-20(16)21-15-33-8-7-29-22(33)23(31-21)32-9-11-35-12-10-32;1-16-5-6-19(30-23(34)17-3-2-4-18(13-17)25(26,27)28)14-20(16)21-15-22-29-7-8-33(22)24(31-21)32-9-11-35-12-10-32;1-15-5-6-18(30-24(34)16-3-2-4-17(13-16)25(26,27)28)14-19(15)22-31-20-7-8-29-21(20)23(32-22)33-9-11-35-12-10-33;1-15-5-6-18(29-24(33)16-3-2-4-17(13-16)25(26,27)28)14-19(15)22-30-20-7-12-35-21(20)23(31-22)32-8-10-34-11-9-32/h3-9,12-14,17H,10-11,15H2,1-2H3,(H,31,35);2*2-6,11-14H,7-10H2,1H3,(H,30,33)(H,31,34);2*2-8,13-15H,9-12H2,1H3,(H,30,34);2-8,13-14,29H,9-12H2,1H3,(H,30,34);2-7,12-14H,8-11H2,1H3,(H,29,33)/t17-;;;;;;/m1....../s1
InChIKeyFFKIJGQALBMVMJ-MFGRGHSBSA-N
XLogP36.05
TPSA540.91 Ų
H-Bond Donors10
H-Bond Acceptors39
Rotatable Bonds28
Heavy Atoms248
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003433.41
LogP ≤ 536.05
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1039

Analyze N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide with MolForge

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Related Compounds

N-[3-[[4-(1-benzofuran-2-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-yl]methyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[[4-(furan-2-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-yl]methyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[(4-phenyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)methyl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[(4-thiophen-2-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)methyl]phenyl]-3-(trifluoromethyl)benzamide
CID 159780650
2-(2-hydroxypropan-2-yl)-N-[6-methyl-5-(4-morpholin-4-yl-1H-imidazo[4,5-c]pyridin-6-yl)-3-pyridinyl]pyridine-4-carboxamide;N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide
CID 161144129
1-[4-methyl-3-[(9-methyl-2-pyridin-3-ylpurin-6-yl)amino]phenyl]-2-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]ethanone;1-[4-methyl-3-[(9-methyl-2-pyridin-4-ylpurin-6-yl)amino]phenyl]-2-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]ethanone;N-[4-methyl-3-[(9-methyl-2-pyridin-3-ylpurin-6-yl)amino]phenyl]-3-(trifluoromethoxy)benzamide;N-[4-methyl-3-[(9-methyl-2-pyridin-3-ylpurin-6-yl)amino]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[(9-methyl-2-thiophen-3-ylpurin-6-yl)amino]phenyl]-3-(trifluoromethyl)benzamide
CID 161981800
1-N-[3-(2,3-dihydro-1-benzofuran-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(4-methylsulfinylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(4-methylthiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(2-morpholin-4-ylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(3-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;ethyl 3-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzoate;methane
CID 158059971
1-N-[3-(2,3-dihydro-1-benzofuran-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzamide;1-[5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]thiophen-2-yl]ethanone;3-N,3-N-dimethyl-1-N-[3-(4-methylsulfinylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(4-methylthiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(2-morpholin-4-ylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(3-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine
CID 158860058
3-[2-(3H-benzimidazol-5-yl)-1,3-thiazol-4-yl]propanal;3-(2-imidazo[1,2-a]pyridin-7-yl-1,3-thiazol-4-yl)propanal;3-[2-(2-methyl-3H-benzimidazol-5-yl)-1,3-thiazol-4-yl]propanal;3-[2-(1-oxo-3H-2-benzofuran-5-yl)-1,3-thiazol-4-yl]propanal;3-[2-(2-oxo-3H-1-benzofuran-5-yl)-1,3-thiazol-4-yl]propanal;3-[2-(2-oxo-3H-1,3-benzoxazol-5-yl)-1,3-thiazol-4-yl]propanal;3-[2-(2-oxo-1,3-dihydrobenzimidazol-5-yl)-1,3-thiazol-4-yl]propanal;3-[2-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1,3-thiazol-4-yl]propanal
CID 159594722
1-N-[3-(2,3-dihydro-1-benzofuran-5-yl)imidazo[1,2-a]pyrazin-8-yl]-3-N,3-N-dimethylbenzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(4-methylsulfinylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(4-methylthiophen-2-yl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(2-morpholin-4-ylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-[3-(3-pyrrolidin-1-ylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;ethyl 3-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzoate
CID 160149694
(4R)-N-[4-[chloro(difluoro)methoxy]phenyl]-6-(furan-3-yl)-4-methyl-3,4-dihydro-1H-[1,4]oxazino[4,3-a]benzimidazole-8-carboxamide;(4R)-N-[4-[chloro(difluoro)methoxy]phenyl]-4-methyl-6-(5-methyl-3-pyridinyl)-3,4-dihydro-2H-[1,3]oxazino[3,2-a]benzimidazole-8-carboxamide;(4R)-N-[4-[chloro(difluoro)methoxy]phenyl]-4-methyl-6-pyridin-3-yl-3,4-dihydro-1H-[1,4]oxazino[4,3-a]benzimidazole-8-carboxamide;(4R)-N-[4-[chloro(difluoro)methoxy]phenyl]-4-methyl-6-(1,3-thiazol-2-yl)-3,4-dihydro-1H-[1,4]oxazino[4,3-a]benzimidazole-8-carboxamide;(4R)-N-[4-[chloro(difluoro)methoxy]phenyl]-4-methyl-6-(1,3-thiazol-4-yl)-3,4-dihydro-2H-[1,3]oxazino[3,2-a]benzimidazole-8-carboxamide;(4R)-N-[4-[chloro(difluoro)methoxy]phenyl]-4-methyl-6-thiophen-2-yl-3,4-dihydro-1H-[1,4]oxazino[4,3-a]benzimidazole-8-carboxamide
CID 160566802
3-[2-(2,6-dimethylmorpholin-4-yl)-5-methylpyrrolo[3,2-d]pyrimidin-4-yl]oxy-4-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]benzamide;3-(2-ethyl-5-methylpyrrolo[3,2-d]pyrimidin-4-yl)oxy-4-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]benzamide;4-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-3-(5-methyl-2-morpholin-4-ylpyrrolo[3,2-d]pyrimidin-4-yl)oxybenzamide;4-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-3-[5-methyl-2-(4-thiophen-3-ylphenyl)pyrrolo[3,2-d]pyrimidin-4-yl]oxybenzamide
CID 160842691
2-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-5-(5-methyl-2-pyridin-3-ylpyrrolo[3,2-d]pyrimidin-4-yl)oxybenzamide;2-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-5-(5-methyl-2-pyridin-4-ylpyrrolo[3,2-d]pyrimidin-4-yl)oxybenzamide;2-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-5-[(2-pyridin-3-yl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]benzamide;2-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-5-[(2-pyridin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]benzamide;4-methyl-N-[3-methyl-4-[(4-methylpiperazin-1-yl)methyl]phenyl]-3-[(2-thiophen-3-yl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]benzamide
CID 161169252
2-[4-[3-[(1-hydroxyimino-2,3-dihydroinden-5-yl)amino]imidazo[1,2-a]pyrazin-2-yl]phenoxy]-N-(2-methoxyethyl)-N-methylacetamide;2-[4-[3-[(1-hydroxyimino-2,3-dihydroinden-5-yl)amino]imidazo[1,2-a]pyrazin-2-yl]phenoxy]-1-morpholin-4-ylethanone;4-[3-[(1-hydroxyimino-2,3-dihydroinden-5-yl)amino]imidazo[1,2-a]pyrazin-2-yl]-N-propan-2-ylbenzamide;(NZ)-N-[5-[[2-(4-methoxy-3-methylphenyl)imidazo[1,2-a]pyrazin-3-yl]amino]-2,3-dihydroinden-1-ylidene]hydroxylamine;(NE)-N-[5-[(2-thiophen-2-ylimidazo[1,2-a]pyrazin-3-yl)amino]-2,3-dihydroinden-1-ylidene]hydroxylamine
CID 172937428

Frequently Asked Questions

What is the IUPAC name of N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide?
The IUPAC name of N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide (CID 158015490) is N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide.
What is the SMILES notation for N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide?
The canonical SMILES for N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide is Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c2oc(=O)[nH]c2c1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)cc2[nH]c(=O)oc12.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2nccn2c(N2CCOCC2)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cn2ccnc2c(N2CCOCC2)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cn2ccnc2c(N2CCOC[C@H]2C)n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2[nH]ccc2n1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2sccc2n1.
What is the InChIKey of N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide?
The InChIKey is FFKIJGQALBMVMJ-MFGRGHSBSA-N. The full InChI is InChI=1S/C26H24F3N5O2.2C26H22F3N3O4.3C25H22F3N5O2.C25H21F3N4O2S/c1-16-6-7-20(31-25(35)18-4-3-5-19(12-18)26(27,28)29)13-21(16)22-14-33-9-8-30-23(33)24(32-22)34-10-11-36-15-17(34)2;1-15-5-6-19(30-24(33)16-3-2-4-18(11-16)26(27,28)29)14-20(15)17-12-21-23(36-25(34)31-21)22(13-17)32-7-9-35-10-8-32;1-15-5-6-18(30-24(33)16-3-2-4-17(11-16)26(27,28)29)12-20(15)21-13-19(32-7-9-35-10-8-32)14-22-23(21)36-25(34)31-22;1-16-5-6-19(30-24(34)17-3-2-4-18(13-17)25(26,27)28)14-20(16)21-15-33-8-7-29-22(33)23(31-21)32-9-11-35-12-10-32;1-16-5-6-19(30-23(34)17-3-2-4-18(13-17)25(26,27)28)14-20(16)21-15-22-29-7-8-33(22)24(31-21)32-9-11-35-12-10-32;1-15-5-6-18(30-24(34)16-3-2-4-17(13-16)25(26,27)28)14-19(15)22-31-20-7-8-29-21(20)23(32-22)33-9-11-35-12-10-33;1-15-5-6-18(29-24(33)16-3-2-4-17(13-16)25(26,27)28)14-19(15)22-30-20-7-12-35-21(20)23(31-22)32-8-10-34-11-9-32/h3-9,12-14,17H,10-11,15H2,1-2H3,(H,31,35);2*2-6,11-14H,7-10H2,1H3,(H,30,33)(H,31,34);2*2-8,13-15H,9-12H2,1H3,(H,30,34);2-8,13-14,29H,9-12H2,1H3,(H,30,34);2-7,12-14H,8-11H2,1H3,(H,29,33)/t17-;;;;;;/m1....../s1.
What are the key properties of N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide?
N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide has a molecular weight of 3433.41 g/mol, XLogP of 36.05, 28 rotatable bonds, 10 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-methyl-3-[8-[(3R)-3-methylmorpholin-4-yl]imidazo[1,2-a]pyrazin-6-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-ylimidazo[1,2-c]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(5-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-7-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(7-morpholin-4-yl-2-oxo-3H-1,3-benzoxazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 158015490), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).