2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide

C233H285Cl9FN85O25 — CID 158020308

IUPAC2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide
SMILESCOc1cc(CCNC(=O)N2CCC3(CC2)CN=C(NC(=O)c2nc(Cl)c(N)nc2N)N3)cc(OC)c1.COc1ccc(CCCNC(=O)N2CCC3(CC2)CN=C(NC(=O)c2nc(Cl)c(N)nc2N)N3)c2ccccc12.Cc1cc(C)c2c(CCNC(=O)N3CCC4(CC3)CN=C(NC(=O)c3nc(Cl)c(N)nc3N)N4)c[nH]c2c1.Cc1cc2[nH]cc(CCNC(=O)N3CCC4(CC3)CN=C(NC(=O)c3nc(Cl)c(N)nc3N)N4)c2cc1C.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCCc4ccccn4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCc4ccc(OCCCCc5ccccc5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCc4ccc(OCCc5ccc(F)cc5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCc4ccc(CN5CCOCC5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCc4cccc(OCc5ccccc5)c4)CC3)N2)nc1Cl
InChIInChI=1S/C31H38ClN9O3.C29H33ClFN9O3.C27H32ClN9O3.C27H30ClN9O3.C25H33ClN10O3.2C25H31ClN10O2.C23H30ClN9O4.C21H27ClN10O2/c32-25-27(34)38-26(33)24(37-25)28(42)39-29-36-20-31(40-29)14-17-41(18-15-31)30(43)35-16-13-22-9-11-23(12-10-22)44-19-5-4-8-21-6-2-1-3-7-21;30-23-25(33)37-24(32)22(36-23)26(41)38-27-35-17-29(39-27)11-14-40(15-12-29)28(42)34-13-9-18-3-7-21(8-4-18)43-16-10-19-1-5-20(31)6-2-19;1-40-19-9-8-16(17-6-2-3-7-18(17)19)5-4-12-31-26(39)37-13-10-27(11-14-37)15-32-25(36-27)35-24(38)20-22(29)34-23(30)21(28)33-20;28-21-23(30)34-22(29)20(33-21)24(38)35-25-32-16-27(36-25)9-11-37(12-10-27)26(39)31-14-18-7-4-8-19(13-18)40-15-17-5-2-1-3-6-17;26-19-21(28)32-20(27)18(31-19)22(37)33-23-30-15-25(34-23)5-7-36(8-6-25)24(38)29-13-16-1-3-17(4-2-16)14-35-9-11-39-12-10-35;1-13-9-16-15(11-30-17(16)10-14(13)2)3-6-29-24(38)36-7-4-25(5-8-36)12-31-23(35-25)34-22(37)18-20(27)33-21(28)19(26)32-18;1-13-9-14(2)17-15(11-30-16(17)10-13)3-6-29-24(38)36-7-4-25(5-8-36)12-31-23(35-25)34-22(37)18-20(27)33-21(28)19(26)32-18;1-36-14-9-13(10-15(11-14)37-2)3-6-27-22(35)33-7-4-23(5-8-33)12-28-21(32-23)31-20(34)16-18(25)30-19(26)17(24)29-16;22-15-17(24)29-16(23)14(28-15)18(33)30-19-27-12-21(31-19)6-10-32(11-7-21)20(34)26-9-3-5-13-4-1-2-8-25-13/h1-3,6-7,9-12H,4-5,8,13-20H2,(H,35,43)(H4,33,34,38)(H2,36,39,40,42);1-8H,9-17H2,(H,34,42)(H4,32,33,37)(H2,35,38,39,41);2-3,6-9H,4-5,10-15H2,1H3,(H,31,39)(H4,29,30,34)(H2,32,35,36,38);1-8,13H,9-12,14-16H2,(H,31,39)(H4,29,30,34)(H2,32,35,36,38);1-4H,5-15H2,(H,29,38)(H4,27,28,32)(H2,30,33,34,37);2*9-11,30H,3-8,12H2,1-2H3,(H,29,38)(H4,27,28,33)(H2,31,34,35,37);9-11H,3-8,12H2,1-2H3,(H,27,35)(H4,25,26,30)(H2,28,31,32,34);1-2,4,8H,3,5-7,9-12H2,(H,26,34)(H4,23,24,29)(H2,27,30,31,33)
InChIKeyFFZCZHNVRFAAJK-UHFFFAOYSA-N
MW5014.49 g/mol
LogP15.97
Rot. Bonds54

About 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide

2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide (PubChem CID 158020308) has the molecular formula C233H285Cl9FN85O25 and a molecular weight of 5014.49 g/mol. Its IUPAC name is 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide.

Molecular Properties

Compound Name2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide
PubChem CID158020308
Molecular FormulaC233H285Cl9FN85O25
Molecular Weight5014.49 g/mol
Exact Mass5007.08
IUPAC Name2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide
SMILESCOc1cc(CCNC(=O)N2CCC3(CC2)CN=C(NC(=O)c2nc(Cl)c(N)nc2N)N3)cc(OC)c1.COc1ccc(CCCNC(=O)N2CCC3(CC2)CN=C(NC(=O)c2nc(Cl)c(N)nc2N)N3)c2ccccc12.Cc1cc(C)c2c(CCNC(=O)N3CCC4(CC3)CN=C(NC(=O)c3nc(Cl)c(N)nc3N)N4)c[nH]c2c1.Cc1cc2[nH]cc(CCNC(=O)N3CCC4(CC3)CN=C(NC(=O)c3nc(Cl)c(N)nc3N)N4)c2cc1C.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCCc4ccccn4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCc4ccc(OCCCCc5ccccc5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCc4ccc(OCCc5ccc(F)cc5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCc4ccc(CN5CCOCC5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCc4cccc(OCc5ccccc5)c4)CC3)N2)nc1Cl
InChIInChI=1S/C31H38ClN9O3.C29H33ClFN9O3.C27H32ClN9O3.C27H30ClN9O3.C25H33ClN10O3.2C25H31ClN10O2.C23H30ClN9O4.C21H27ClN10O2/c32-25-27(34)38-26(33)24(37-25)28(42)39-29-36-20-31(40-29)14-17-41(18-15-31)30(43)35-16-13-22-9-11-23(12-10-22)44-19-5-4-8-21-6-2-1-3-7-21;30-23-25(33)37-24(32)22(36-23)26(41)38-27-35-17-29(39-27)11-14-40(15-12-29)28(42)34-13-9-18-3-7-21(8-4-18)43-16-10-19-1-5-20(31)6-2-19;1-40-19-9-8-16(17-6-2-3-7-18(17)19)5-4-12-31-26(39)37-13-10-27(11-14-37)15-32-25(36-27)35-24(38)20-22(29)34-23(30)21(28)33-20;28-21-23(30)34-22(29)20(33-21)24(38)35-25-32-16-27(36-25)9-11-37(12-10-27)26(39)31-14-18-7-4-8-19(13-18)40-15-17-5-2-1-3-6-17;26-19-21(28)32-20(27)18(31-19)22(37)33-23-30-15-25(34-23)5-7-36(8-6-25)24(38)29-13-16-1-3-17(4-2-16)14-35-9-11-39-12-10-35;1-13-9-16-15(11-30-17(16)10-14(13)2)3-6-29-24(38)36-7-4-25(5-8-36)12-31-23(35-25)34-22(37)18-20(27)33-21(28)19(26)32-18;1-13-9-14(2)17-15(11-30-16(17)10-13)3-6-29-24(38)36-7-4-25(5-8-36)12-31-23(35-25)34-22(37)18-20(27)33-21(28)19(26)32-18;1-36-14-9-13(10-15(11-14)37-2)3-6-27-22(35)33-7-4-23(5-8-33)12-28-21(32-23)31-20(34)16-18(25)30-19(26)17(24)29-16;22-15-17(24)29-16(23)14(28-15)18(33)30-19-27-12-21(31-19)6-10-32(11-7-21)20(34)26-9-3-5-13-4-1-2-8-25-13/h1-3,6-7,9-12H,4-5,8,13-20H2,(H,35,43)(H4,33,34,38)(H2,36,39,40,42);1-8H,9-17H2,(H,34,42)(H4,32,33,37)(H2,35,38,39,41);2-3,6-9H,4-5,10-15H2,1H3,(H,31,39)(H4,29,30,34)(H2,32,35,36,38);1-8,13H,9-12,14-16H2,(H,31,39)(H4,29,30,34)(H2,32,35,36,38);1-4H,5-15H2,(H,29,38)(H4,27,28,32)(H2,30,33,34,37);2*9-11,30H,3-8,12H2,1-2H3,(H,29,38)(H4,27,28,33)(H2,31,34,35,37);9-11H,3-8,12H2,1-2H3,(H,27,35)(H4,25,26,30)(H2,28,31,32,34);1-2,4,8H,3,5-7,9-12H2,(H,26,34)(H4,23,24,29)(H2,27,30,31,33)
InChIKeyFFZCZHNVRFAAJK-UHFFFAOYSA-N
XLogP15.97
TPSA1585.17 Ų
H-Bond Donors47
H-Bond Acceptors81
Rotatable Bonds54
Heavy Atoms353
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005014.49
LogP ≤ 515.97
H-Bond Donors ≤ 547
H-Bond Acceptors ≤ 1081

Analyze 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide?
The IUPAC name of 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide (CID 158020308) is 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide.
What is the SMILES notation for 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide?
The canonical SMILES for 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide is COc1cc(CCNC(=O)N2CCC3(CC2)CN=C(NC(=O)c2nc(Cl)c(N)nc2N)N3)cc(OC)c1.COc1ccc(CCCNC(=O)N2CCC3(CC2)CN=C(NC(=O)c2nc(Cl)c(N)nc2N)N3)c2ccccc12.Cc1cc(C)c2c(CCNC(=O)N3CCC4(CC3)CN=C(NC(=O)c3nc(Cl)c(N)nc3N)N4)c[nH]c2c1.Cc1cc2[nH]cc(CCNC(=O)N3CCC4(CC3)CN=C(NC(=O)c3nc(Cl)c(N)nc3N)N4)c2cc1C.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCCc4ccccn4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCc4ccc(OCCCCc5ccccc5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCCc4ccc(OCCc5ccc(F)cc5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCc4ccc(CN5CCOCC5)cc4)CC3)N2)nc1Cl.Nc1nc(N)c(C(=O)NC2=NCC3(CCN(C(=O)NCc4cccc(OCc5ccccc5)c4)CC3)N2)nc1Cl.
What is the InChIKey of 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide?
The InChIKey is FFZCZHNVRFAAJK-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H38ClN9O3.C29H33ClFN9O3.C27H32ClN9O3.C27H30ClN9O3.C25H33ClN10O3.2C25H31ClN10O2.C23H30ClN9O4.C21H27ClN10O2/c32-25-27(34)38-26(33)24(37-25)28(42)39-29-36-20-31(40-29)14-17-41(18-15-31)30(43)35-16-13-22-9-11-23(12-10-22)44-19-5-4-8-21-6-2-1-3-7-21;30-23-25(33)37-24(32)22(36-23)26(41)38-27-35-17-29(39-27)11-14-40(15-12-29)28(42)34-13-9-18-3-7-21(8-4-18)43-16-10-19-1-5-20(31)6-2-19;1-40-19-9-8-16(17-6-2-3-7-18(17)19)5-4-12-31-26(39)37-13-10-27(11-14-37)15-32-25(36-27)35-24(38)20-22(29)34-23(30)21(28)33-20;28-21-23(30)34-22(29)20(33-21)24(38)35-25-32-16-27(36-25)9-11-37(12-10-27)26(39)31-14-18-7-4-8-19(13-18)40-15-17-5-2-1-3-6-17;26-19-21(28)32-20(27)18(31-19)22(37)33-23-30-15-25(34-23)5-7-36(8-6-25)24(38)29-13-16-1-3-17(4-2-16)14-35-9-11-39-12-10-35;1-13-9-16-15(11-30-17(16)10-14(13)2)3-6-29-24(38)36-7-4-25(5-8-36)12-31-23(35-25)34-22(37)18-20(27)33-21(28)19(26)32-18;1-13-9-14(2)17-15(11-30-16(17)10-13)3-6-29-24(38)36-7-4-25(5-8-36)12-31-23(35-25)34-22(37)18-20(27)33-21(28)19(26)32-18;1-36-14-9-13(10-15(11-14)37-2)3-6-27-22(35)33-7-4-23(5-8-33)12-28-21(32-23)31-20(34)16-18(25)30-19(26)17(24)29-16;22-15-17(24)29-16(23)14(28-15)18(33)30-19-27-12-21(31-19)6-10-32(11-7-21)20(34)26-9-3-5-13-4-1-2-8-25-13/h1-3,6-7,9-12H,4-5,8,13-20H2,(H,35,43)(H4,33,34,38)(H2,36,39,40,42);1-8H,9-17H2,(H,34,42)(H4,32,33,37)(H2,35,38,39,41);2-3,6-9H,4-5,10-15H2,1H3,(H,31,39)(H4,29,30,34)(H2,32,35,36,38);1-8,13H,9-12,14-16H2,(H,31,39)(H4,29,30,34)(H2,32,35,36,38);1-4H,5-15H2,(H,29,38)(H4,27,28,32)(H2,30,33,34,37);2*9-11,30H,3-8,12H2,1-2H3,(H,29,38)(H4,27,28,33)(H2,31,34,35,37);9-11H,3-8,12H2,1-2H3,(H,27,35)(H4,25,26,30)(H2,28,31,32,34);1-2,4,8H,3,5-7,9-12H2,(H,26,34)(H4,23,24,29)(H2,27,30,31,33).
What are the key properties of 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide?
2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide has a molecular weight of 5014.49 g/mol, XLogP of 15.97, 54 rotatable bonds, 47 hydrogen bond donors, and 81 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(3,5-dimethoxyphenyl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(4,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-(5,6-dimethyl-1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-[2-(4-fluorophenyl)ethoxy]phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[3-(4-methoxynaphthalen-1-yl)propyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[2-[4-(4-phenylbutoxy)phenyl]ethyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-[(3-phenylmethoxyphenyl)methyl]-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide;2-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]-N-(3-pyridin-2-ylpropyl)-1,3,8-triazaspiro[4.5]dec-2-ene-8-carboxamide is sourced from PubChem (CID 158020308), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).