4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine

C201H236N74O8S5 — CID 158021284

IUPAC4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine
SMILESCC(C)Cc1ncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)s1.CN(C)S(=O)(=O)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cc1.CN(C)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.CSc1ncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.Cc1nc(-c2ccccc2)sc1-c1cnn2c(N)cc(C3CCCNC3)nc12.NC(=O)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cc1.Nc1cc(C2CCCNC2)nc2c(-c3ccc(CO)cc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccc4c(c3)OCO4)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccn[nH]3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnco3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cncs3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ncon3)cnn12
InChIInChI=1S/C21H22N6S.C19H24N6O2S.C18H23N7.C18H20N6O.C18H24N6S.C18H19N5O2.C18H21N5O.C16H19N7S.C14H17N7.C14H16N6O.C14H16N6S.C13H15N7O/c1-13-19(28-21(25-13)14-6-3-2-4-7-14)16-12-24-27-18(22)10-17(26-20(16)27)15-8-5-9-23-11-15;1-24(2)28(26,27)15-7-5-13(6-8-15)16-12-22-25-18(20)10-17(23-19(16)25)14-4-3-9-21-11-14;1-24(2)17-6-5-12(10-21-17)14-11-22-25-16(19)8-15(23-18(14)25)13-4-3-7-20-9-13;19-16-8-15(13-2-1-7-21-9-13)23-18-14(10-22-24(16)18)11-3-5-12(6-4-11)17(20)25;1-11(2)6-17-21-10-15(25-17)13-9-22-24-16(19)7-14(23-18(13)24)12-4-3-5-20-8-12;19-17-7-14(12-2-1-5-20-8-12)22-18-13(9-21-23(17)18)11-3-4-15-16(6-11)25-10-24-15;19-17-8-16(14-2-1-7-20-9-14)22-18-15(10-21-23(17)18)13-5-3-12(11-24)4-6-13;1-24-16-19-7-11(8-20-16)12-9-21-23-14(17)5-13(22-15(12)23)10-3-2-4-18-6-10;15-13-6-12(9-2-1-4-16-7-9)19-14-10(8-18-21(13)14)11-3-5-17-20-11;2*15-13-4-11(9-2-1-3-16-5-9)19-14-10(6-18-20(13)14)12-7-17-8-21-12;14-11-4-10(8-2-1-3-15-5-8)18-13-9(6-17-20(11)13)12-16-7-21-19-12/h2-4,6-7,10,12,15,23H,5,8-9,11,22H2,1H3;5-8,10,12,14,21H,3-4,9,11,20H2,1-2H3;5-6,8,10-11,13,20H,3-4,7,9,19H2,1-2H3;3-6,8,10,13,21H,1-2,7,9,19H2,(H2,20,25);7,9-12,20H,3-6,8,19H2,1-2H3;3-4,6-7,9,12,20H,1-2,5,8,10,19H2;3-6,8,10,14,20,24H,1-2,7,9,11,19H2;5,7-10,18H,2-4,6,17H2,1H3;3,5-6,8-9,16H,1-2,4,7,15H2,(H,17,20);2*4,6-9,16H,1-3,5,15H2;4,6-8,15H,1-3,5,14H2
InChIKeyFGBZIMWRICKMLC-UHFFFAOYSA-N
MW3976.94 g/mol
LogP23.53
Rot. Bonds33

About 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine

4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine (PubChem CID 158021284) has the molecular formula C201H236N74O8S5 and a molecular weight of 3976.94 g/mol. Its IUPAC name is 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine.

Molecular Properties

Compound Name4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine
PubChem CID158021284
Molecular FormulaC201H236N74O8S5
Molecular Weight3976.94 g/mol
Exact Mass3973.89
IUPAC Name4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine
SMILESCC(C)Cc1ncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)s1.CN(C)S(=O)(=O)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cc1.CN(C)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.CSc1ncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.Cc1nc(-c2ccccc2)sc1-c1cnn2c(N)cc(C3CCCNC3)nc12.NC(=O)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cc1.Nc1cc(C2CCCNC2)nc2c(-c3ccc(CO)cc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccc4c(c3)OCO4)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccn[nH]3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnco3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cncs3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ncon3)cnn12
InChIInChI=1S/C21H22N6S.C19H24N6O2S.C18H23N7.C18H20N6O.C18H24N6S.C18H19N5O2.C18H21N5O.C16H19N7S.C14H17N7.C14H16N6O.C14H16N6S.C13H15N7O/c1-13-19(28-21(25-13)14-6-3-2-4-7-14)16-12-24-27-18(22)10-17(26-20(16)27)15-8-5-9-23-11-15;1-24(2)28(26,27)15-7-5-13(6-8-15)16-12-22-25-18(20)10-17(23-19(16)25)14-4-3-9-21-11-14;1-24(2)17-6-5-12(10-21-17)14-11-22-25-16(19)8-15(23-18(14)25)13-4-3-7-20-9-13;19-16-8-15(13-2-1-7-21-9-13)23-18-14(10-22-24(16)18)11-3-5-12(6-4-11)17(20)25;1-11(2)6-17-21-10-15(25-17)13-9-22-24-16(19)7-14(23-18(13)24)12-4-3-5-20-8-12;19-17-7-14(12-2-1-5-20-8-12)22-18-13(9-21-23(17)18)11-3-4-15-16(6-11)25-10-24-15;19-17-8-16(14-2-1-7-20-9-14)22-18-15(10-21-23(17)18)13-5-3-12(11-24)4-6-13;1-24-16-19-7-11(8-20-16)12-9-21-23-14(17)5-13(22-15(12)23)10-3-2-4-18-6-10;15-13-6-12(9-2-1-4-16-7-9)19-14-10(8-18-21(13)14)11-3-5-17-20-11;2*15-13-4-11(9-2-1-3-16-5-9)19-14-10(6-18-20(13)14)12-7-17-8-21-12;14-11-4-10(8-2-1-3-15-5-8)18-13-9(6-17-20(11)13)12-16-7-21-19-12/h2-4,6-7,10,12,15,23H,5,8-9,11,22H2,1H3;5-8,10,12,14,21H,3-4,9,11,20H2,1-2H3;5-6,8,10-11,13,20H,3-4,7,9,19H2,1-2H3;3-6,8,10,13,21H,1-2,7,9,19H2,(H2,20,25);7,9-12,20H,3-6,8,19H2,1-2H3;3-4,6-7,9,12,20H,1-2,5,8,10,19H2;3-6,8,10,14,20,24H,1-2,7,9,11,19H2;5,7-10,18H,2-4,6,17H2,1H3;3,5-6,8-9,16H,1-2,4,7,15H2,(H,17,20);2*4,6-9,16H,1-3,5,15H2;4,6-8,15H,1-3,5,14H2
InChIKeyFGBZIMWRICKMLC-UHFFFAOYSA-N
XLogP23.53
TPSA1112.25 Ų
H-Bond Donors27
H-Bond Acceptors83
Rotatable Bonds33
Heavy Atoms288
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003976.94
LogP ≤ 523.53
H-Bond Donors ≤ 527
H-Bond Acceptors ≤ 1083

Analyze 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine with MolForge

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Frequently Asked Questions

What is the IUPAC name of 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine?
The IUPAC name of 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CID 158021284) is 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine.
What is the SMILES notation for 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine?
The canonical SMILES for 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine is CC(C)Cc1ncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)s1.CN(C)S(=O)(=O)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cc1.CN(C)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.CSc1ncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.Cc1nc(-c2ccccc2)sc1-c1cnn2c(N)cc(C3CCCNC3)nc12.NC(=O)c1ccc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cc1.Nc1cc(C2CCCNC2)nc2c(-c3ccc(CO)cc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccc4c(c3)OCO4)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccn[nH]3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnco3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cncs3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ncon3)cnn12.
What is the InChIKey of 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine?
The InChIKey is FGBZIMWRICKMLC-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H22N6S.C19H24N6O2S.C18H23N7.C18H20N6O.C18H24N6S.C18H19N5O2.C18H21N5O.C16H19N7S.C14H17N7.C14H16N6O.C14H16N6S.C13H15N7O/c1-13-19(28-21(25-13)14-6-3-2-4-7-14)16-12-24-27-18(22)10-17(26-20(16)27)15-8-5-9-23-11-15;1-24(2)28(26,27)15-7-5-13(6-8-15)16-12-22-25-18(20)10-17(23-19(16)25)14-4-3-9-21-11-14;1-24(2)17-6-5-12(10-21-17)14-11-22-25-16(19)8-15(23-18(14)25)13-4-3-7-20-9-13;19-16-8-15(13-2-1-7-21-9-13)23-18-14(10-22-24(16)18)11-3-5-12(6-4-11)17(20)25;1-11(2)6-17-21-10-15(25-17)13-9-22-24-16(19)7-14(23-18(13)24)12-4-3-5-20-8-12;19-17-7-14(12-2-1-5-20-8-12)22-18-13(9-21-23(17)18)11-3-4-15-16(6-11)25-10-24-15;19-17-8-16(14-2-1-7-20-9-14)22-18-15(10-21-23(17)18)13-5-3-12(11-24)4-6-13;1-24-16-19-7-11(8-20-16)12-9-21-23-14(17)5-13(22-15(12)23)10-3-2-4-18-6-10;15-13-6-12(9-2-1-4-16-7-9)19-14-10(8-18-21(13)14)11-3-5-17-20-11;2*15-13-4-11(9-2-1-3-16-5-9)19-14-10(6-18-20(13)14)12-7-17-8-21-12;14-11-4-10(8-2-1-3-15-5-8)18-13-9(6-17-20(11)13)12-16-7-21-19-12/h2-4,6-7,10,12,15,23H,5,8-9,11,22H2,1H3;5-8,10,12,14,21H,3-4,9,11,20H2,1-2H3;5-6,8,10-11,13,20H,3-4,7,9,19H2,1-2H3;3-6,8,10,13,21H,1-2,7,9,19H2,(H2,20,25);7,9-12,20H,3-6,8,19H2,1-2H3;3-4,6-7,9,12,20H,1-2,5,8,10,19H2;3-6,8,10,14,20,24H,1-2,7,9,11,19H2;5,7-10,18H,2-4,6,17H2,1H3;3,5-6,8-9,16H,1-2,4,7,15H2,(H,17,20);2*4,6-9,16H,1-3,5,15H2;4,6-8,15H,1-3,5,14H2.
What are the key properties of 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine?
4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine has a molecular weight of 3976.94 g/mol, XLogP of 23.53, 33 rotatable bonds, 27 hydrogen bond donors, and 83 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)benzamide;4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-dimethylbenzenesulfonamide;[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)phenyl]methanol;3-(1,3-benzodioxol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[6-(dimethylamino)-3-pyridinyl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-[2-(2-methylpropyl)-1,3-thiazol-5-yl]-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(2-methylsulfanylpyrimidin-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2,4-oxadiazol-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,3-oxazol-5-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1,3-thiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7-amine is sourced from PubChem (CID 158021284), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).