1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone

C146H143ClFN31O10 — CID 158022175

IUPAC1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone
SMILESCc1[nH]nc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)c1C.Cc1[nH]nc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)c1Cl.Cc1c[nH]c(C(=O)Cc2cnc3n[nH]c(-c4ccc(F)cc4)c3c2)c1C.Cc1c[nH]c(C(=O)Cc2cnc3n[nH]c(C)c3c2)c1C.Cc1cc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)n[nH]1.Cc1ccc(-c2cc3cc(CC(=O)c4n[nH]c5ccccc45)cnc3[nH]2)cc1.Cc1nn(C)cc1C1=Cc2cc(CC(=O)c3n[nH]c(C)c3C)ccc2C1
InChIInChI=1S/C23H25N5O2.C23H18N4O.C22H22ClN5O2.C22H23N5O2.C21H22N4O.C20H17FN4O.C15H16N4O/c1-13-14(2)26-27-21(13)20(29)10-15-9-18-11-19(25-22(18)24-12-15)16-5-7-28(8-6-16)23(30)17-3-4-17;1-14-6-8-16(9-7-14)20-12-17-10-15(13-24-23(17)25-20)11-21(28)22-18-4-2-3-5-19(18)26-27-22;1-12-19(23)20(27-26-12)18(29)9-13-8-16-10-17(25-21(16)24-11-13)14-4-6-28(7-5-14)22(30)15-2-3-15;1-13-8-19(26-25-13)20(28)10-14-9-17-11-18(24-21(17)23-12-14)15-4-6-27(7-5-15)22(29)16-2-3-16;1-12-13(2)22-23-21(12)20(26)8-15-5-6-16-9-18(10-17(16)7-15)19-11-25(4)24-14(19)3;1-11-9-22-18(12(11)2)17(26)8-13-7-16-19(24-25-20(16)23-10-13)14-3-5-15(21)6-4-14;1-8-6-16-14(9(8)2)13(20)5-11-4-12-10(3)18-19-15(12)17-7-11/h5,9,11-12,17H,3-4,6-8,10H2,1-2H3,(H,24,25)(H,26,27);2-10,12-13H,11H2,1H3,(H,24,25)(H,26,27);4,8,10-11,15H,2-3,5-7,9H2,1H3,(H,24,25)(H,26,27);4,8-9,11-12,16H,2-3,5-7,10H2,1H3,(H,23,24)(H,25,26);5-7,10-11H,8-9H2,1-4H3,(H,22,23);3-7,9-10,22H,8H2,1-2H3,(H,23,24,25);4,6-7,16H,5H2,1-3H3,(H,17,18,19)
InChIKeyFGENHODZEJHZAX-UHFFFAOYSA-N
MW2546.41 g/mol
LogP25.30
Rot. Bonds30

About 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone

1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone (PubChem CID 158022175) has the molecular formula C146H143ClFN31O10 and a molecular weight of 2546.41 g/mol. Its IUPAC name is 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone.

Molecular Properties

Compound Name1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone
PubChem CID158022175
Molecular FormulaC146H143ClFN31O10
Molecular Weight2546.41 g/mol
Exact Mass2544.13
IUPAC Name1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone
SMILESCc1[nH]nc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)c1C.Cc1[nH]nc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)c1Cl.Cc1c[nH]c(C(=O)Cc2cnc3n[nH]c(-c4ccc(F)cc4)c3c2)c1C.Cc1c[nH]c(C(=O)Cc2cnc3n[nH]c(C)c3c2)c1C.Cc1cc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)n[nH]1.Cc1ccc(-c2cc3cc(CC(=O)c4n[nH]c5ccccc45)cnc3[nH]2)cc1.Cc1nn(C)cc1C1=Cc2cc(CC(=O)c3n[nH]c(C)c3C)ccc2C1
InChIInChI=1S/C23H25N5O2.C23H18N4O.C22H22ClN5O2.C22H23N5O2.C21H22N4O.C20H17FN4O.C15H16N4O/c1-13-14(2)26-27-21(13)20(29)10-15-9-18-11-19(25-22(18)24-12-15)16-5-7-28(8-6-16)23(30)17-3-4-17;1-14-6-8-16(9-7-14)20-12-17-10-15(13-24-23(17)25-20)11-21(28)22-18-4-2-3-5-19(18)26-27-22;1-12-19(23)20(27-26-12)18(29)9-13-8-16-10-17(25-21(16)24-11-13)14-4-6-28(7-5-14)22(30)15-2-3-15;1-13-8-19(26-25-13)20(28)10-14-9-17-11-18(24-21(17)23-12-14)15-4-6-27(7-5-15)22(29)16-2-3-16;1-12-13(2)22-23-21(12)20(26)8-15-5-6-16-9-18(10-17(16)7-15)19-11-25(4)24-14(19)3;1-11-9-22-18(12(11)2)17(26)8-13-7-16-19(24-25-20(16)23-10-13)14-3-5-15(21)6-4-14;1-8-6-16-14(9(8)2)13(20)5-11-4-12-10(3)18-19-15(12)17-7-11/h5,9,11-12,17H,3-4,6-8,10H2,1-2H3,(H,24,25)(H,26,27);2-10,12-13H,11H2,1H3,(H,24,25)(H,26,27);4,8,10-11,15H,2-3,5-7,9H2,1H3,(H,24,25)(H,26,27);4,8-9,11-12,16H,2-3,5-7,10H2,1H3,(H,23,24)(H,25,26);5-7,10-11H,8-9H2,1-4H3,(H,22,23);3-7,9-10,22H,8H2,1-2H3,(H,23,24,25);4,6-7,16H,5H2,1-3H3,(H,17,18,19)
InChIKeyFGENHODZEJHZAX-UHFFFAOYSA-N
XLogP25.30
TPSA571.08 Ų
H-Bond Donors13
H-Bond Acceptors25
Rotatable Bonds30
Heavy Atoms189
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002546.41
LogP ≤ 525.30
H-Bond Donors ≤ 513
H-Bond Acceptors ≤ 1025

Analyze 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone with MolForge

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Related Compounds

N-[1-[5-chloro-2-[5-[(1R)-1-[[6-[4-(1H-indazol-5-ylamino)pyrimidin-2-yl]-1H-indole-2-carbonyl]amino]ethyl]-2-(trifluoromethyl)pyridin-3-yl]pyridin-4-yl]piperidin-4-yl]-6-[4-[4-(1H-pyrazol-4-yl)anilino]pyrimidin-2-yl]-1H-indole-2-carboxamide
CID 137387455
(4R)-4-[3-[3-(1-aminoethenyl)-4-fluorophenyl]-2-pyridinyl]-5-(3,5-difluorophenyl)-1-(5,6-dimethylisoindol-2-yl)pentan-2-one;3-[2-[(2R)-5-[6-(aminomethyl)-1H-indol-3-yl]-1-(3,5-difluorophenyl)-4-oxopentan-2-yl]-3-pyridinyl]-N-methylbenzamide;5-[2-[(1S)-1-[[2-(5-chloroindol-1-yl)acetyl]amino]-2-(3,5-difluorophenyl)ethyl]-3-pyridinyl]-2-fluoro-N-methylbenzamide;5-[2-[(1S)-2-(3,5-difluorophenyl)-1-[2-(5,6-dimethylbenzimidazol-1-yl)butanoylamino]ethyl]-3-pyridinyl]-2-fluoro-N-methylbenzamide;5-[2-[(2R)-1-(3,5-difluorophenyl)-7-methyl-4-oxo-5-[3-(trifluoromethyl)pyrazol-1-yl]octan-2-yl]-3-pyridinyl]-2-fluoro-N-methylbenzamide
CID 157158955
(5-chloro-1H-indazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5,6-difluoro-1H-indazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-imidazol-5-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-1H-indazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(7-methyl-2H-indazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;2H-pyrazolo[3,4-b]pyridin-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-pyrrolo[3,2-b]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-pyrrolo[2,3-c]pyridin-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 157188127
(3S,4R)-1-[2-[(2S)-1-(3,6-dichloropyridine-2-carbonyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-1-[2-[(2S)-1-(2,4-difluorobenzoyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-1-[2-[(2S)-1-(3,4-difluoro-2-methylbenzoyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-1-[2-[(2S)-1-(4,5-difluoro-2-methylbenzoyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-1-[2-[(2S)-1-(1H-indole-7-carbonyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-4-methyl-1-[6-methyl-2-[(2S)-1-[6-(trifluoromethyl)pyridine-2-carbonyl]piperidin-2-yl]pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidine-3-carbonitrile
CID 157212630
[4-[8-tert-butyl-6-(4-methylphenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-pyridin-2-ylmethanone;[3,3-dimethyl-4-[8-propan-2-yl-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazine-2-carbonyl]piperazin-1-yl]-(5-methyl-1H-pyrazol-3-yl)methanone;4-[6-(4-fluoro-3-methylphenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(2-methyl-1H-imidazol-5-yl)piperazin-2-one;4-[6-(4-fluoro-3-methylphenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(3H-pyrrol-5-yl)piperazin-2-one
CID 157222251
(6-chloro-2-methylimidazo[1,2-b]pyridazin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;imidazo[1,2-b]pyridazin-6-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-indol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 157421955
(4R)-4-[3-(7H-cyclopenta[b]pyridin-3-yl)-6-[2-(1H-pyrrolo[2,3-b]pyridin-5-yl)ethynyl]-2-pyridinyl]-1-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindazol-1-yl]-5-(3,5-difluorophenyl)pentan-2-one;N-[(1S)-1-[5-(2-cyclopropylethynyl)-3-(2-methyl-3-oxo-1H-isoindol-5-yl)-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-2-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindol-1-yl]acetamide;6-[2-[(2R)-5-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindol-1-yl]-1-(3,5-difluorophenyl)-4-oxopentan-2-yl]-6-(2-pyrimidin-5-ylethynyl)-3-pyridinyl]-2,3-dihydroinden-1-one
CID 157435113
CID 157602215
CID 157602215
N-cyclopropyl-4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluorobenzamide;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2,6-difluoro-N-methylbenzamide;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-N-ethyl-2-fluorobenzamide;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluoro-N,N-dimethylbenzamide;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluoro-N-methylbenzamide;4-[3-[difluoro-(4-fluoro-2-methylindazol-5-yl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-2-fluoro-N-propan-2-ylbenzamide
CID 157656021
(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-1-(3-bromo-5-cyclopropyl-1,2,4-triazol-1-yl)-5-(3,5-difluorophenyl)pentan-2-one;(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-1-(4-chloroimidazo[4,5-c]pyridin-1-yl)-5-(3,5-difluorophenyl)pentan-2-one;(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-1-[4,4-difluoro-3-(trifluoromethyl)-5,5a,6,6a-tetrahydrocyclopropa[g]indazol-1-yl]pentan-2-one;(4R)-4-[3-(3-acetylphenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-1-(2-methylindol-1-yl)pentan-2-one;(4R)-5-(3,5-difluorophenyl)-1-(6-fluoro-3H-inden-1-yl)-4-[5-(4-methylphenyl)pyrimidin-4-yl]pentan-2-one
CID 157684037
(4R)-4-[3-(7H-cyclopenta[b]pyridin-3-yl)-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)-2-pyridinyl]-1-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindazol-1-yl]-5-(3,5-difluorophenyl)pentan-2-one;6-[2-[(2R)-5-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindazol-1-yl]-1-(3,5-difluorophenyl)-4-oxopentan-2-yl]-6-(3-hydroxy-3-methylbut-1-ynyl)-3-pyridinyl]-2,3-dihydroinden-1-one;6-[6-[(2R)-5-[3-(difluoromethyl)-4,4,7,7-tetrafluoro-5,6-dihydroindazol-1-yl]-1-(3,5-difluorophenyl)-4-oxopentan-2-yl]-5-(3-oxo-1,2-dihydroinden-5-yl)-3-pyridinyl]-2,3-dihydroisoindol-1-one
CID 157768731
(7-chloro-2H-indazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5,6-difluoro-1H-indazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(7-fluoro-2H-indazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(6-fluoro-1-propan-2-ylindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-1-propan-2-ylindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;2H-pyrazolo[3,4-b]pyridin-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1H-pyrazolo[4,3-c]pyridin-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 157805183

Frequently Asked Questions

What is the IUPAC name of 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone?
The IUPAC name of 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone (CID 158022175) is 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone.
What is the SMILES notation for 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone?
The canonical SMILES for 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone is Cc1[nH]nc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)c1C.Cc1[nH]nc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)c1Cl.Cc1c[nH]c(C(=O)Cc2cnc3n[nH]c(-c4ccc(F)cc4)c3c2)c1C.Cc1c[nH]c(C(=O)Cc2cnc3n[nH]c(C)c3c2)c1C.Cc1cc(C(=O)Cc2cnc3[nH]c(C4=CCN(C(=O)C5CC5)CC4)cc3c2)n[nH]1.Cc1ccc(-c2cc3cc(CC(=O)c4n[nH]c5ccccc45)cnc3[nH]2)cc1.Cc1nn(C)cc1C1=Cc2cc(CC(=O)c3n[nH]c(C)c3C)ccc2C1.
What is the InChIKey of 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone?
The InChIKey is FGENHODZEJHZAX-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25N5O2.C23H18N4O.C22H22ClN5O2.C22H23N5O2.C21H22N4O.C20H17FN4O.C15H16N4O/c1-13-14(2)26-27-21(13)20(29)10-15-9-18-11-19(25-22(18)24-12-15)16-5-7-28(8-6-16)23(30)17-3-4-17;1-14-6-8-16(9-7-14)20-12-17-10-15(13-24-23(17)25-20)11-21(28)22-18-4-2-3-5-19(18)26-27-22;1-12-19(23)20(27-26-12)18(29)9-13-8-16-10-17(25-21(16)24-11-13)14-4-6-28(7-5-14)22(30)15-2-3-15;1-13-8-19(26-25-13)20(28)10-14-9-17-11-18(24-21(17)23-12-14)15-4-6-27(7-5-15)22(29)16-2-3-16;1-12-13(2)22-23-21(12)20(26)8-15-5-6-16-9-18(10-17(16)7-15)19-11-25(4)24-14(19)3;1-11-9-22-18(12(11)2)17(26)8-13-7-16-19(24-25-20(16)23-10-13)14-3-5-15(21)6-4-14;1-8-6-16-14(9(8)2)13(20)5-11-4-12-10(3)18-19-15(12)17-7-11/h5,9,11-12,17H,3-4,6-8,10H2,1-2H3,(H,24,25)(H,26,27);2-10,12-13H,11H2,1H3,(H,24,25)(H,26,27);4,8,10-11,15H,2-3,5-7,9H2,1H3,(H,24,25)(H,26,27);4,8-9,11-12,16H,2-3,5-7,10H2,1H3,(H,23,24)(H,25,26);5-7,10-11H,8-9H2,1-4H3,(H,22,23);3-7,9-10,22H,8H2,1-2H3,(H,23,24,25);4,6-7,16H,5H2,1-3H3,(H,17,18,19).
What are the key properties of 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone?
1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone has a molecular weight of 2546.41 g/mol, XLogP of 25.30, 30 rotatable bonds, 13 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(4-chloro-5-methyl-1H-pyrazol-3-yl)-2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(4,5-dimethyl-1H-pyrazol-3-yl)ethanone;2-[2-[1-(cyclopropanecarbonyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-1-(5-methyl-1H-pyrazol-3-yl)ethanone;1-(4,5-dimethyl-1H-pyrazol-3-yl)-2-[2-(1,3-dimethylpyrazol-4-yl)-1H-inden-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-[3-(4-fluorophenyl)-2H-pyrazolo[3,4-b]pyridin-5-yl]ethanone;1-(3,4-dimethyl-1H-pyrrol-2-yl)-2-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)ethanone;1-(1H-indazol-3-yl)-2-[2-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone is sourced from PubChem (CID 158022175), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).