N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide

C103H120N30O10 — CID 158023659

About N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide

N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide (PubChem CID 158023659) has the molecular formula C103H120N30O10 and a molecular weight of 1938.29 g/mol. Its IUPAC name is N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
• PubChem CID: 158023659
• Molecular Formula: C103H120N30O10
• Molecular Weight: 1938.29 g/mol
• Exact Mass: 1936.98
• IUPAC Name: N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
• SMILES: CC(C)[C@@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.CC(C)[C@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.O=C(Nc1cc(N2CCCCC2CCO)nc2c(C3CC3)cnn12)c1cccnc1.O=C(Nc1cc(N2CCCCC2CO)nc2c(C3CC3)cnn12)c1cccnc1.O=C(Nc1cc(N2CCC[C@@H]2CO)nc2c(C3CC3)cnn12)c1cccnc1
• InChI: InChI=1S/C22H26N6O2.C21H24N6O2.C20H22N6O2.2C20H24N6O2/c29-11-8-17-5-1-2-10-27(17)19-12-20(26-22(30)16-4-3-9-23-13-16)28-21(25-19)18(14-24-28)15-6-7-15;28-13-16-5-1-2-9-26(16)18-10-19(25-21(29)15-4-3-8-22-11-15)27-20(24-18)17(12-23-27)14-6-7-14;27-12-15-4-2-8-25(15)17-9-18(24-20(28)14-3-1-7-21-10-14)26-19(23-17)16(11-22-26)13-5-6-13;2*1-12(2)16(11-27)23-17-8-18(25-20(28)14-4-3-7-21-9-14)26-19(24-17)15(10-22-26)13-5-6-13/h3-4,9,12-15,17,29H,1-2,5-8,10-11H2,(H,26,30);3-4,8,10-12,14,16,28H,1-2,5-7,9,13H2,(H,25,29);1,3,7,9-11,13,15,27H,2,4-6,8,12H2,(H,24,28);2*3-4,7-10,12-13,16,27H,5-6,11H2,1-2H3,(H,23,24)(H,25,28)/t;;15-;2*16-/m..110/s1
• InChIKey: FGIWZBVXDUBPEP-SBGBOLJJSA-N
• XLogP: 13.18
• TPSA: 495.83 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 35
• Rotatable Bonds: 30
• Heavy Atoms: 143
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1938.29
LogP ≤ 5	13.18
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

The IUPAC name of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide (CID 158023659) is N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide.

What is the SMILES notation for N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

The canonical SMILES for N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide is CC(C)[C@@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.CC(C)[C@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.O=C(Nc1cc(N2CCCCC2CCO)nc2c(C3CC3)cnn12)c1cccnc1.O=C(Nc1cc(N2CCCCC2CO)nc2c(C3CC3)cnn12)c1cccnc1.O=C(Nc1cc(N2CCC[C@@H]2CO)nc2c(C3CC3)cnn12)c1cccnc1.

What is the InChIKey of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

The InChIKey is FGIWZBVXDUBPEP-SBGBOLJJSA-N. The full InChI is InChI=1S/C22H26N6O2.C21H24N6O2.C20H22N6O2.2C20H24N6O2/c29-11-8-17-5-1-2-10-27(17)19-12-20(26-22(30)16-4-3-9-23-13-16)28-21(25-19)18(14-24-28)15-6-7-15;28-13-16-5-1-2-9-26(16)18-10-19(25-21(29)15-4-3-8-22-11-15)27-20(24-18)17(12-23-27)14-6-7-14;27-12-15-4-2-8-25(15)17-9-18(24-20(28)14-3-1-7-21-10-14)26-19(23-17)16(11-22-26)13-5-6-13;2*1-12(2)16(11-27)23-17-8-18(25-20(28)14-4-3-7-21-9-14)26-19(24-17)15(10-22-26)13-5-6-13/h3-4,9,12-15,17,29H,1-2,5-8,10-11H2,(H,26,30);3-4,8,10-12,14,16,28H,1-2,5-7,9,13H2,(H,25,29);1,3,7,9-11,13,15,27H,2,4-6,8,12H2,(H,24,28);2*3-4,7-10,12-13,16,27H,5-6,11H2,1-2H3,(H,23,24)(H,25,28)/t;;15-;2*16-/m..110/s1.

What are the key properties of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?

N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide has a molecular weight of 1938.29 g/mol, XLogP of 13.18, 30 rotatable bonds, 12 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide is sourced from PubChem (CID 158023659), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).