N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

C132H156F4N22O23S5 — CID 158048265

About N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide (PubChem CID 158048265) has the molecular formula C132H156F4N22O23S5 and a molecular weight of 2655.16 g/mol. Its IUPAC name is N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
• PubChem CID: 158048265
• Molecular Formula: C132H156F4N22O23S5
• Molecular Weight: 2655.16 g/mol
• Exact Mass: 2653.03
• IUPAC Name: N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
• SMILES: CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CC(F)(F)CC3(C)C)n2)c1.CC(C)COc1ccccc1-c1ccc(C(=O)NS(=O)(=O)c2ccc[nH]c2=O)c(N2C[C@@H](C)CC2(C)C)n1.CC1CN(c2ncccc2C(=O)CS(=O)(=O)c2cccc(OCC3OCc4ccccc4O3)n2)C(C)(C)C1.CC1CN(c2ncccc2C(=O)NS(=O)(=O)c2cccc(OCCC3CCCC3)n2)C(C)(C)C1.COc1ncc(-c2ccc(C(=O)NS(=O)(=O)c3cccnc3N)c(N3C[C@@H](C)CC3(C)C)n2)cc1F
• InChI: InChI=1S/C28H34N4O5S.C28H31N3O6S.C27H30F3N5O4S.C25H34N4O4S.C24H27FN6O4S/c1-18(2)17-37-23-10-7-6-9-20(23)22-13-12-21(25(30-22)32-16-19(3)15-28(32,4)5)26(33)31-38(35,36)24-11-8-14-29-27(24)34;1-19-14-28(2,3)31(15-19)27-21(9-7-13-29-27)22(32)18-38(33,34)25-12-6-11-24(30-25)35-17-26-36-16-20-8-4-5-10-23(20)37-26;1-16(2)13-39-19-11-17(10-18(28)12-19)21-9-8-20(24(32-21)35-15-27(29,30)14-26(35,3)4)25(36)34-40(37,38)23-7-5-6-22(31)33-23;1-18-16-25(2,3)29(17-18)23-20(10-7-14-26-23)24(30)28-34(31,32)22-12-6-11-21(27-22)33-15-13-19-8-4-5-9-19;1-14-11-24(2,3)31(13-14)21-16(22(32)30-36(33,34)19-6-5-9-27-20(19)26)7-8-18(29-21)15-10-17(25)23(35-4)28-12-15/h6-14,18-19H,15-17H2,1-5H3,(H,29,34)(H,31,33);4-13,19,26H,14-18H2,1-3H3;5-12,16H,13-15H2,1-4H3,(H2,31,33)(H,34,36);6-7,10-12,14,18-19H,4-5,8-9,13,15-17H2,1-3H3,(H,28,30);5-10,12,14H,11,13H2,1-4H3,(H2,26,27)(H,30,32)/t19-;;;;14-/m0...0/s1
• InChIKey: FJEDQFQLUCIMLO-FDNCXMDESA-N
• XLogP: 20.12
• TPSA: 598.78 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 40
• Rotatable Bonds: 38
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2655.16
LogP ≤ 5	20.12
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	40

Frequently Asked Questions

What is the IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

The IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide (CID 158048265) is N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide.

What is the SMILES notation for N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

The canonical SMILES for N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide is CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CC(F)(F)CC3(C)C)n2)c1.CC(C)COc1ccccc1-c1ccc(C(=O)NS(=O)(=O)c2ccc[nH]c2=O)c(N2C[C@@H](C)CC2(C)C)n1.CC1CN(c2ncccc2C(=O)CS(=O)(=O)c2cccc(OCC3OCc4ccccc4O3)n2)C(C)(C)C1.CC1CN(c2ncccc2C(=O)NS(=O)(=O)c2cccc(OCCC3CCCC3)n2)C(C)(C)C1.COc1ncc(-c2ccc(C(=O)NS(=O)(=O)c3cccnc3N)c(N3C[C@@H](C)CC3(C)C)n2)cc1F.

What is the InChIKey of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

The InChIKey is FJEDQFQLUCIMLO-FDNCXMDESA-N. The full InChI is InChI=1S/C28H34N4O5S.C28H31N3O6S.C27H30F3N5O4S.C25H34N4O4S.C24H27FN6O4S/c1-18(2)17-37-23-10-7-6-9-20(23)22-13-12-21(25(30-22)32-16-19(3)15-28(32,4)5)26(33)31-38(35,36)24-11-8-14-29-27(24)34;1-19-14-28(2,3)31(15-19)27-21(9-7-13-29-27)22(32)18-38(33,34)25-12-6-11-24(30-25)35-17-26-36-16-20-8-4-5-10-23(20)37-26;1-16(2)13-39-19-11-17(10-18(28)12-19)21-9-8-20(24(32-21)35-15-27(29,30)14-26(35,3)4)25(36)34-40(37,38)23-7-5-6-22(31)33-23;1-18-16-25(2,3)29(17-18)23-20(10-7-14-26-23)24(30)28-34(31,32)22-12-6-11-21(27-22)33-15-13-19-8-4-5-9-19;1-14-11-24(2,3)31(13-14)21-16(22(32)30-36(33,34)19-6-5-9-27-20(19)26)7-8-18(29-21)15-10-17(25)23(35-4)28-12-15/h6-14,18-19H,15-17H2,1-5H3,(H,29,34)(H,31,33);4-13,19,26H,14-18H2,1-3H3;5-12,16H,13-15H2,1-4H3,(H2,31,33)(H,34,36);6-7,10-12,14,18-19H,4-5,8-9,13,15-17H2,1-3H3,(H,28,30);5-10,12,14H,11,13H2,1-4H3,(H2,26,27)(H,30,32)/t19-;;;;14-/m0...0/s1.

What are the key properties of N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide has a molecular weight of 2655.16 g/mol, XLogP of 20.12, 38 rotatable bonds, 7 hydrogen bond donors, and 40 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(6-amino-2-pyridinyl)sulfonyl]-2-(4,4-difluoro-2,2-dimethylpyrrolidin-1-yl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-(5-fluoro-6-methoxy-3-pyridinyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;2-[[6-(4H-1,3-benzodioxin-2-ylmethoxy)-2-pyridinyl]sulfonyl]-1-[2-(2,2,4-trimethylpyrrolidin-1-yl)-3-pyridinyl]ethanone;N-[[6-(2-cyclopentylethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[2-(2-methylpropoxy)phenyl]-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide is sourced from PubChem (CID 158048265), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).