3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide

C123H122F3N23O18 — CID 158052375

About 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide

3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide (PubChem CID 158052375) has the molecular formula C123H122F3N23O18 and a molecular weight of 2267.47 g/mol. Its IUPAC name is 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide.

Molecular Properties

• Compound Name: 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide
• PubChem CID: 158052375
• Molecular Formula: C123H122F3N23O18
• Molecular Weight: 2267.47 g/mol
• Exact Mass: 2265.93
• IUPAC Name: 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide
• SMILES: Nc1cccnc1C(=O)Nc1ccc2c(OCC3COCCO3)nccc2c1.Nc1cccnc1C(=O)Nc1cnc2c(OCC3CCCCC3)nccc2c1.O=C(Nc1ccc2c(OCC3COCCO3)nccc2c1)c1ccc(F)cn1.O=C(Nc1ccc2c(OCC3COCCO3)nccc2c1)c1cccc(F)n1.O=C(Nc1cnc2c(OCC3CCCCC3)nccc2c1)c1ccc(F)cn1.O=C(Nc1cnc2c(OCC3CCCCC3)nccc2c1)c1ccccn1
• InChI: InChI=1S/C21H21FN4O2.C21H23N5O2.C21H22N4O2.2C20H18FN3O4.C20H20N4O4/c22-16-6-7-18(24-11-16)20(27)26-17-10-15-8-9-23-21(19(15)25-12-17)28-13-14-4-2-1-3-5-14;22-17-7-4-9-23-19(17)20(27)26-16-11-15-8-10-24-21(18(15)25-12-16)28-13-14-5-2-1-3-6-14;26-20(18-8-4-5-10-22-18)25-17-12-16-9-11-23-21(19(16)24-13-17)27-14-15-6-2-1-3-7-15;21-14-1-4-18(23-10-14)19(25)24-15-2-3-17-13(9-15)5-6-22-20(17)28-12-16-11-26-7-8-27-16;21-18-3-1-2-17(24-18)19(25)23-14-4-5-16-13(10-14)6-7-22-20(16)28-12-15-11-26-8-9-27-15;21-17-2-1-6-22-18(17)19(25)24-14-3-4-16-13(10-14)5-7-23-20(16)28-12-15-11-26-8-9-27-15/h6-12,14H,1-5,13H2,(H,26,27);4,7-12,14H,1-3,5-6,13,22H2,(H,26,27);4-5,8-13,15H,1-3,6-7,14H2,(H,25,26);1-6,9-10,16H,7-8,11-12H2,(H,24,25);1-7,10,15H,8-9,11-12H2,(H,23,25);1-7,10,15H,8-9,11-12,21H2,(H,24,25)
• InChIKey: FJQDMHKZMHTDBU-UHFFFAOYSA-N
• XLogP: 20.32
• TPSA: 530.75 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 35
• Rotatable Bonds: 30
• Heavy Atoms: 167
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2267.47
LogP ≤ 5	20.32
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	35

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide?

The IUPAC name of 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide (CID 158052375) is 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide.

What is the SMILES notation for 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide?

The canonical SMILES for 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide is Nc1cccnc1C(=O)Nc1ccc2c(OCC3COCCO3)nccc2c1.Nc1cccnc1C(=O)Nc1cnc2c(OCC3CCCCC3)nccc2c1.O=C(Nc1ccc2c(OCC3COCCO3)nccc2c1)c1ccc(F)cn1.O=C(Nc1ccc2c(OCC3COCCO3)nccc2c1)c1cccc(F)n1.O=C(Nc1cnc2c(OCC3CCCCC3)nccc2c1)c1ccc(F)cn1.O=C(Nc1cnc2c(OCC3CCCCC3)nccc2c1)c1ccccn1.

What is the InChIKey of 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide?

The InChIKey is FJQDMHKZMHTDBU-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H21FN4O2.C21H23N5O2.C21H22N4O2.2C20H18FN3O4.C20H20N4O4/c22-16-6-7-18(24-11-16)20(27)26-17-10-15-8-9-23-21(19(15)25-12-17)28-13-14-4-2-1-3-5-14;22-17-7-4-9-23-19(17)20(27)26-16-11-15-8-10-24-21(18(15)25-12-16)28-13-14-5-2-1-3-6-14;26-20(18-8-4-5-10-22-18)25-17-12-16-9-11-23-21(19(16)24-13-17)27-14-15-6-2-1-3-7-15;21-14-1-4-18(23-10-14)19(25)24-15-2-3-17-13(9-15)5-6-22-20(17)28-12-16-11-26-7-8-27-16;21-18-3-1-2-17(24-18)19(25)23-14-4-5-16-13(10-14)6-7-22-20(16)28-12-15-11-26-8-9-27-15;21-17-2-1-6-22-18(17)19(25)24-14-3-4-16-13(10-14)5-7-23-20(16)28-12-15-11-26-8-9-27-15/h6-12,14H,1-5,13H2,(H,26,27);4,7-12,14H,1-3,5-6,13,22H2,(H,26,27);4-5,8-13,15H,1-3,6-7,14H2,(H,25,26);1-6,9-10,16H,7-8,11-12H2,(H,24,25);1-7,10,15H,8-9,11-12H2,(H,23,25);1-7,10,15H,8-9,11-12,21H2,(H,24,25).

What are the key properties of 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide?

3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide has a molecular weight of 2267.47 g/mol, XLogP of 20.32, 30 rotatable bonds, 8 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;3-amino-N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]pyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]-5-fluoropyridine-2-carboxamide;N-[8-(cyclohexylmethoxy)-1,7-naphthyridin-3-yl]pyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-5-fluoropyridine-2-carboxamide;N-[1-(1,4-dioxan-2-ylmethoxy)isoquinolin-6-yl]-6-fluoropyridine-2-carboxamide is sourced from PubChem (CID 158052375), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).