N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide

C107H99F27N10O16 — CID 158056877

About N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide

N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide (PubChem CID 158056877) has the molecular formula C107H99F27N10O16 and a molecular weight of 2293.97 g/mol. Its IUPAC name is N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide.

Molecular Properties

• Compound Name: N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide
• PubChem CID: 158056877
• Molecular Formula: C107H99F27N10O16
• Molecular Weight: 2293.97 g/mol
• Exact Mass: 2292.68
• IUPAC Name: N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide
• SMILES: CC(=O)Nc1ccc2c(ccc(=O)n2Cc2ccc(C(C)(O)C(F)(F)F)cc2)c1.COCC(=O)Nc1ccc2c(c1)CCC(=O)N2Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.COCC(=O)Nc1ccc2c(c1)CCCN2Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.COCC(=O)Nc1ccc2c(c1)CCN2Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.COCC(=O)Nc1ccc2c(ccn2Cc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)c1
• InChI: InChI=1S/C22H20F6N2O4.C22H22F6N2O3.C21H20F6N2O3.C21H18F6N2O3.C21H19F3N2O3/c1-34-12-18(31)29-16-7-8-17-14(10-16)4-9-19(32)30(17)11-13-2-5-15(6-3-13)20(33,21(23,24)25)22(26,27)28;1-33-13-19(31)29-17-8-9-18-15(11-17)3-2-10-30(18)12-14-4-6-16(7-5-14)20(32,21(23,24)25)22(26,27)28;2*1-32-12-18(30)28-16-6-7-17-14(10-16)8-9-29(17)11-13-2-4-15(5-3-13)19(31,20(22,23)24)21(25,26)27;1-13(27)25-17-8-9-18-15(11-17)5-10-19(28)26(18)12-14-3-6-16(7-4-14)20(2,29)21(22,23)24/h2-3,5-8,10,33H,4,9,11-12H2,1H3,(H,29,31);4-9,11,32H,2-3,10,12-13H2,1H3,(H,29,31);2-7,10,31H,8-9,11-12H2,1H3,(H,28,30);2-10,31H,11-12H2,1H3,(H,28,30);3-11,29H,12H2,1-2H3,(H,25,27)
• InChIKey: FKDVMUDBSSUYLG-UHFFFAOYSA-N
• XLogP: 21.11
• TPSA: 337.29 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 20
• Rotatable Bonds: 28
• Heavy Atoms: 160
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2293.97
LogP ≤ 5	21.11
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	20

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide?

The IUPAC name of N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide (CID 158056877) is N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide.

What is the SMILES notation for N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide?

The canonical SMILES for N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide is CC(=O)Nc1ccc2c(ccc(=O)n2Cc2ccc(C(C)(O)C(F)(F)F)cc2)c1.COCC(=O)Nc1ccc2c(c1)CCC(=O)N2Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.COCC(=O)Nc1ccc2c(c1)CCCN2Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.COCC(=O)Nc1ccc2c(c1)CCN2Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.COCC(=O)Nc1ccc2c(ccn2Cc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)c1.

What is the InChIKey of N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide?

The InChIKey is FKDVMUDBSSUYLG-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H20F6N2O4.C22H22F6N2O3.C21H20F6N2O3.C21H18F6N2O3.C21H19F3N2O3/c1-34-12-18(31)29-16-7-8-17-14(10-16)4-9-19(32)30(17)11-13-2-5-15(6-3-13)20(33,21(23,24)25)22(26,27)28;1-33-13-19(31)29-17-8-9-18-15(11-17)3-2-10-30(18)12-14-4-6-16(7-5-14)20(32,21(23,24)25)22(26,27)28;2*1-32-12-18(30)28-16-6-7-17-14(10-16)8-9-29(17)11-13-2-4-15(5-3-13)19(31,20(22,23)24)21(25,26)27;1-13(27)25-17-8-9-18-15(11-17)5-10-19(28)26(18)12-14-3-6-16(7-4-14)20(2,29)21(22,23)24/h2-3,5-8,10,33H,4,9,11-12H2,1H3,(H,29,31);4-9,11,32H,2-3,10,12-13H2,1H3,(H,29,31);2-7,10,31H,8-9,11-12H2,1H3,(H,28,30);2-10,31H,11-12H2,1H3,(H,28,30);3-11,29H,12H2,1-2H3,(H,25,27).

What are the key properties of N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide?

N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide has a molecular weight of 2293.97 g/mol, XLogP of 21.11, 28 rotatable bonds, 10 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2,3-dihydroindol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-3,4-dihydro-2H-quinolin-6-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]indol-5-yl]-2-methoxyacetamide;N-[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-2-oxo-3,4-dihydroquinolin-6-yl]-2-methoxyacetamide;N-[2-oxo-1-[[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]methyl]quinolin-6-yl]acetamide is sourced from PubChem (CID 158056877), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).