(4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide

C152H139F8N15O9 — CID 158058882

About (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide

(4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide (PubChem CID 158058882) has the molecular formula C152H139F8N15O9 and a molecular weight of 2471.86 g/mol. Its IUPAC name is (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide.

Molecular Properties

• Compound Name: (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide
• PubChem CID: 158058882
• Molecular Formula: C152H139F8N15O9
• Molecular Weight: 2471.86 g/mol
• Exact Mass: 2470.08
• IUPAC Name: (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide
• SMILES: COc1ccc(-c2cccnc2[C@@H](CC(=O)CC2=CCc3ccc(O)cc32)Cc2cc(F)cc(F)c2)cc1.Cc1ccccc1-c1cccnc1[C@@H](Cc1ccccc1)NC(=O)Cc1c[nH]c2ccc(O)cc12.Cc1ccccc1-c1cccnc1[C@@H](Cc1ccccc1)NC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2.Cc1ccccc1-c1cccnc1[C@H](Cc1ccccc1)NC(=O)Cc1c[nH]c2ccc(O)cc12.Cc1ccccc1-c1cccnc1[C@H](Cc1ccccc1)NC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2
• InChI: InChI=1S/C32H27F2NO3.2C30H29F3N4O.2C30H27N3O2/c1-38-29-10-7-21(8-11-29)30-3-2-12-35-32(30)24(13-20-14-25(33)18-26(34)15-20)17-28(37)16-23-5-4-22-6-9-27(36)19-31(22)23;2*1-20-10-5-6-13-22(20)23-15-9-17-34-28(23)25(18-21-11-3-2-4-12-21)35-27(38)19-37-26-16-8-7-14-24(26)29(36-37)30(31,32)33;2*1-20-8-5-6-11-24(20)25-12-7-15-31-30(25)28(16-21-9-3-2-4-10-21)33-29(35)17-22-19-32-27-14-13-23(34)18-26(22)27/h2-3,5-12,14-15,18-19,24,36H,4,13,16-17H2,1H3;2*2-6,9-13,15,17,25H,7-8,14,16,18-19H2,1H3,(H,35,38);2*2-15,18-19,28,32,34H,16-17H2,1H3,(H,33,35)/t24-;2*25-;2*28-/m11010/s1
• InChIKey: FKKACYPPYHFCIT-DZSPQNPXSA-N
• XLogP: 31.33
• TPSA: 335.06 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 18
• Rotatable Bonds: 37
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2471.86
LogP ≤ 5	31.33
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	18

Frequently Asked Questions

What is the IUPAC name of (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

The IUPAC name of (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide (CID 158058882) is (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide.

What is the SMILES notation for (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

The canonical SMILES for (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide is COc1ccc(-c2cccnc2[C@@H](CC(=O)CC2=CCc3ccc(O)cc32)Cc2cc(F)cc(F)c2)cc1.Cc1ccccc1-c1cccnc1[C@@H](Cc1ccccc1)NC(=O)Cc1c[nH]c2ccc(O)cc12.Cc1ccccc1-c1cccnc1[C@@H](Cc1ccccc1)NC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2.Cc1ccccc1-c1cccnc1[C@H](Cc1ccccc1)NC(=O)Cc1c[nH]c2ccc(O)cc12.Cc1ccccc1-c1cccnc1[C@H](Cc1ccccc1)NC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2.

What is the InChIKey of (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

The InChIKey is FKKACYPPYHFCIT-DZSPQNPXSA-N. The full InChI is InChI=1S/C32H27F2NO3.2C30H29F3N4O.2C30H27N3O2/c1-38-29-10-7-21(8-11-29)30-3-2-12-35-32(30)24(13-20-14-25(33)18-26(34)15-20)17-28(37)16-23-5-4-22-6-9-27(36)19-31(22)23;2*1-20-10-5-6-13-22(20)23-15-9-17-34-28(23)25(18-21-11-3-2-4-12-21)35-27(38)19-37-26-16-8-7-14-24(26)29(36-37)30(31,32)33;2*1-20-8-5-6-11-24(20)25-12-7-15-31-30(25)28(16-21-9-3-2-4-10-21)33-29(35)17-22-19-32-27-14-13-23(34)18-26(22)27/h2-3,5-12,14-15,18-19,24,36H,4,13,16-17H2,1H3;2*2-6,9-13,15,17,25H,7-8,14,16,18-19H2,1H3,(H,35,38);2*2-15,18-19,28,32,34H,16-17H2,1H3,(H,33,35)/t24-;2*25-;2*28-/m11010/s1.

What are the key properties of (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

(4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide has a molecular weight of 2471.86 g/mol, XLogP of 31.33, 37 rotatable bonds, 9 hydrogen bond donors, and 18 hydrogen bond acceptors.

Where does this data come from?

All data for (4R)-5-(3,5-difluorophenyl)-1-(6-hydroxy-3H-inden-1-yl)-4-[3-(4-methoxyphenyl)-2-pyridinyl]pentan-2-one;2-(5-hydroxy-1H-indol-3-yl)-N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;2-(5-hydroxy-1H-indol-3-yl)-N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]acetamide;N-[(1S)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(2-methylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide is sourced from PubChem (CID 158058882), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).