6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine

C99H81F17N22O6 — CID 158064125

About 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine

6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine (PubChem CID 158064125) has the molecular formula C99H81F17N22O6 and a molecular weight of 1997.85 g/mol. Its IUPAC name is 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine.

Molecular Properties

• Compound Name: 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine
• PubChem CID: 158064125
• Molecular Formula: C99H81F17N22O6
• Molecular Weight: 1997.85 g/mol
• Exact Mass: 1996.64
• IUPAC Name: 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine
• SMILES: CCc1nc(C)c(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)n1Cc1ccccc1.COc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C(=O)O)nc3ccccn23)c1.COc1cc(Nc2ccc(OC(F)F)cc2)nc(-c2c(C(F)(F)F)nc3ccccn23)c1.Cc1nn(C)c(C)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1noc(C)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1
• InChI: InChI=1S/C24H22F3N5.C21H15F5N4O2.C21H15F3N4O3.C17H16F3N5.C16H13F3N4O/c1-3-22-29-16(2)23(32(22)15-17-7-5-4-6-8-17)20-13-28-14-21(31-20)30-19-11-9-18(10-12-19)24(25,26)27;1-31-14-10-15(18-19(21(24,25)26)29-17-4-2-3-9-30(17)18)28-16(11-14)27-12-5-7-13(8-6-12)32-20(22)23;1-31-14-10-15(19-18(20(29)30)27-17-4-2-3-9-28(17)19)26-16(11-14)25-13-7-5-12(6-8-13)21(22,23)24;1-10-16(11(2)25(3)24-10)14-8-21-9-15(23-14)22-13-6-4-12(5-7-13)17(18,19)20;1-9-15(10(2)24-23-9)13-7-20-8-14(22-13)21-12-5-3-11(4-6-12)16(17,18)19/h4-14H,3,15H2,1-2H3,(H,30,31);2-11,20H,1H3,(H,27,28);2-11H,1H3,(H,25,26)(H,29,30);4-9H,1-3H3,(H,22,23);3-8H,1-2H3,(H,21,22)
• InChIKey: FLABJJXWHFBYBM-UHFFFAOYSA-N
• XLogP: 25.42
• TPSA: 324.53 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 27
• Rotatable Bonds: 23
• Heavy Atoms: 144
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1997.85
LogP ≤ 5	25.42
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine?

The IUPAC name of 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine (CID 158064125) is 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine.

What is the SMILES notation for 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine?

The canonical SMILES for 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine is CCc1nc(C)c(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)n1Cc1ccccc1.COc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C(=O)O)nc3ccccn23)c1.COc1cc(Nc2ccc(OC(F)F)cc2)nc(-c2c(C(F)(F)F)nc3ccccn23)c1.Cc1nn(C)c(C)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1noc(C)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.

What is the InChIKey of 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine?

The InChIKey is FLABJJXWHFBYBM-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H22F3N5.C21H15F5N4O2.C21H15F3N4O3.C17H16F3N5.C16H13F3N4O/c1-3-22-29-16(2)23(32(22)15-17-7-5-4-6-8-17)20-13-28-14-21(31-20)30-19-11-9-18(10-12-19)24(25,26)27;1-31-14-10-15(18-19(21(24,25)26)29-17-4-2-3-9-30(17)18)28-16(11-14)27-12-5-7-13(8-6-12)32-20(22)23;1-31-14-10-15(19-18(20(29)30)27-17-4-2-3-9-28(17)19)26-16(11-14)25-13-7-5-12(6-8-13)21(22,23)24;1-10-16(11(2)25(3)24-10)14-8-21-9-15(23-14)22-13-6-4-12(5-7-13)17(18,19)20;1-9-15(10(2)24-23-9)13-7-20-8-14(22-13)21-12-5-3-11(4-6-12)16(17,18)19/h4-14H,3,15H2,1-2H3,(H,30,31);2-11,20H,1H3,(H,27,28);2-11H,1H3,(H,25,26)(H,29,30);4-9H,1-3H3,(H,22,23);3-8H,1-2H3,(H,21,22).

What are the key properties of 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine?

6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine has a molecular weight of 1997.85 g/mol, XLogP of 25.42, 23 rotatable bonds, 6 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-benzyl-2-ethyl-5-methylimidazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(difluoromethoxy)phenyl]-4-methoxy-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amine;6-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;3-[4-methoxy-6-[4-(trifluoromethyl)anilino]-2-pyridinyl]imidazo[1,2-a]pyridine-2-carboxylic acid;N-[4-(trifluoromethyl)phenyl]-6-(1,3,5-trimethylpyrazol-4-yl)pyrazin-2-amine is sourced from PubChem (CID 158064125), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).