N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide

C153H132Cl4F17N31O20S — CID 158065368

IUPACN-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide
SMILESCn1c(C#N)ccc1-c1cc(C(=O)Nc2ccc(OC(F)(F)Cl)cc2)cnc1N1CC[C@@H](O)C1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)[nH]1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)[nH]1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccc2N2CC[C@@H](O)C2)[nH]1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1.O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1
InChIInChI=1S/C23H20ClF2N5O3.C23H19F3N4O3.2C22H18ClF2N5O3.C21H19ClF2N4O3.C21H19F3N4O3.C21H19F3N4O2S/c1-30-16(11-27)4-7-20(30)19-10-14(12-28-21(19)31-9-8-17(32)13-31)22(33)29-15-2-5-18(6-3-15)34-23(24,25)26;24-23(25,26)33-18-5-2-15(3-6-18)29-22(32)14-1-8-21(30-10-9-17(31)13-30)19(11-14)20-7-4-16(12-27)28-20;2*23-22(24,25)33-17-4-1-14(2-5-17)29-21(32)13-9-18(19-6-3-15(10-26)28-19)20(27-11-13)30-8-7-16(31)12-30;3*22-21(23,24)31-16-5-3-14(4-6-16)27-20(30)13-10-17(18-2-1-8-25-18)19(26-11-13)28-9-7-15(29)12-28/h2-7,10,12,17,32H,8-9,13H2,1H3,(H,29,33);1-8,11,17,28,31H,9-10,13H2,(H,29,32);2*1-6,9,11,16,28,31H,7-8,12H2,(H,29,32);3*1-6,8,10-11,15,25,29H,7,9,12H2,(H,27,30)/t2*17-;2*16-;3*15-/m1111111/s1
InChIKeyFLDSLPJKMUVNKT-ALLCUJASSA-N
MW3221.78 g/mol
LogP28.48
Rot. Bonds39

About N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide

N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide (PubChem CID 158065368) has the molecular formula C153H132Cl4F17N31O20S and a molecular weight of 3221.78 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide
PubChem CID158065368
Molecular FormulaC153H132Cl4F17N31O20S
Molecular Weight3221.78 g/mol
Exact Mass3217.85
IUPAC NameN-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide
SMILESCn1c(C#N)ccc1-c1cc(C(=O)Nc2ccc(OC(F)(F)Cl)cc2)cnc1N1CC[C@@H](O)C1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)[nH]1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)[nH]1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccc2N2CC[C@@H](O)C2)[nH]1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1.O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1
InChIInChI=1S/C23H20ClF2N5O3.C23H19F3N4O3.2C22H18ClF2N5O3.C21H19ClF2N4O3.C21H19F3N4O3.C21H19F3N4O2S/c1-30-16(11-27)4-7-20(30)19-10-14(12-28-21(19)31-9-8-17(32)13-31)22(33)29-15-2-5-18(6-3-15)34-23(24,25)26;24-23(25,26)33-18-5-2-15(3-6-18)29-22(32)14-1-8-21(30-10-9-17(31)13-30)19(11-14)20-7-4-16(12-27)28-20;2*23-22(24,25)33-17-4-1-14(2-5-17)29-21(32)13-9-18(19-6-3-15(10-26)28-19)20(27-11-13)30-8-7-16(31)12-30;3*22-21(23,24)31-16-5-3-14(4-6-16)27-20(30)13-10-17(18-2-1-8-25-18)19(26-11-13)28-9-7-15(29)12-28/h2-7,10,12,17,32H,8-9,13H2,1H3,(H,29,33);1-8,11,17,28,31H,9-10,13H2,(H,29,32);2*1-6,9,11,16,28,31H,7-8,12H2,(H,29,32);3*1-6,8,10-11,15,25,29H,7,9,12H2,(H,27,30)/t2*17-;2*16-;3*15-/m1111111/s1
InChIKeyFLDSLPJKMUVNKT-ALLCUJASSA-N
XLogP28.48
TPSA695.54 Ų
H-Bond Donors20
H-Bond Acceptors39
Rotatable Bonds39
Heavy Atoms226
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003221.78
LogP ≤ 528.48
H-Bond Donors ≤ 520
H-Bond Acceptors ≤ 1039

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'alkyl_halide', 'substructure': 'N/A'}

Analyze N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide with MolForge

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Related Compounds

N-[4-[chloro(difluoro)methoxy]phenyl]-5-[5-[[(4R)-1-[5-[[4-[chloro(difluoro)methoxy]phenyl]carbamoyl]-3-(5-cyano-1-methylpyrrol-2-yl)pyridin-2-yl]-4-hydroxypyrrolidin-3-yl]methyl-methylcarbamoyl]-1H-pyrrol-2-yl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide
CID 134511582
5-(4-cyano-3-pyridinyl)-6-[(3R)-3-methylpyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(6-ethyl-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-6-[(3R)-3-methylpyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(2-methyl-3-pyridinyl)-6-[(3R)-3-methylpyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-methyl-3-pyridinyl)-6-[(3R)-3-methylpyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(6-methyl-3-pyridinyl)-6-[(3R)-3-methylpyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157086001
N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]-5-(5-ethynyl-1H-pyrrol-2-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-[5-(dimethylcarbamoyl)-1H-pyrrol-2-yl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;5-(5-cyano-1H-pyrrol-2-yl)-6-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157133902
5-(5-cyano-3-pyridinyl)-N-[3-fluoro-4-(trifluoromethoxy)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;5-(5-cyano-3-pyridinyl)-6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide;5-(5-cyano-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-N-[3-fluoro-4-(trifluoromethoxy)phenyl]-6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-N-[3-fluoro-4-(trifluoromethoxy)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide
CID 157308010
4-[(3S,4S)-3-amino-4-hydroxypyrrolidin-1-yl]-N-[4-[chloro(difluoro)methoxy]phenyl]-3-(1H-pyrazol-5-yl)benzamide;6-[(3S,4S)-3-amino-4-methoxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-4-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]-3-(1H-pyrazol-5-yl)benzamide;5-(3-cyano-1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[5-(hydroxymethyl)-1H-pyrazol-3-yl]-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157422805
6-[(3R)-3-aminopyrrolidin-1-yl]-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-aminopyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-aminopyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(4-cyano-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;5-(6-chloro-5-fluoro-3-pyridinyl)-6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(5-cyano-3-pyridinyl)-6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(6-cyano-3-pyridinyl)-6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157428190
N-[4-[chloro(difluoro)methoxy]phenyl]-6-(3,3-difluoropyrrolidin-1-yl)-5-pyrimidin-5-ylpyridine-3-carboxamide;6-(3,3-difluoropyrrolidin-1-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-(3-hydroxy-3-methylpyrrolidin-1-yl)-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(3-hydroxy-3-methylpyrrolidin-1-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxy-3-methylpyrrolidin-1-yl]-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-hydroxy-3-methylpyrrolidin-1-yl]-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157433635
5-(4-cyano-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[(3R)-3-hydroxypyrrolidin-1-yl]-3-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(3-hydroxypyrrolidin-1-yl)-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-hydroxypyrrolidin-1-yl]-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[(3R)-3-hydroxypyrrolidin-1-yl]-3-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(3-hydroxypyrrolidin-1-yl)-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157464326
N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2-chloro-5-fluoro-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(4-fluoro-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(4-methyl-3-pyridinyl)pyridine-3-carboxamide;5-(2,6-difluoro-4-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(3-hydroxypyrrolidin-1-yl)-5-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyridin-2-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(3-hydroxypyrrolidin-1-yl)-N-[4-(trifluoromethoxy)phenyl]-5-[6-(trifluoromethyl)-3-pyridinyl]pyridine-3-carboxamide
CID 157481764
N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2-chloro-5-fluoro-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(4-fluoro-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(4-methyl-3-pyridinyl)pyridine-3-carboxamide;6-(3-hydroxypyrrolidin-1-yl)-5-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyridin-2-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(3-hydroxypyrrolidin-1-yl)-N-[4-(trifluoromethoxy)phenyl]-5-[6-(trifluoromethyl)-3-pyridinyl]pyridine-3-carboxamide
CID 157494562
5-(6-amino-5-fluoro-3-pyridinyl)-N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;5-(6-amino-5-fluoro-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,6-difluoro-4-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;5-(5-cyano-3-pyridinyl)-N-[4-(1,1-difluoroethoxy)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-(1,1-difluoroethoxy)phenyl]-5-(5-fluoro-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;5-(5-fluoro-3-pyridinyl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]-5-[5-(trifluoromethyl)-3-pyridinyl]pyridine-3-carboxamide
CID 157587665
5-(6-ethyl-3-pyridinyl)-6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[6-(hydroxymethyl)-3-pyridinyl]-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-(hydroxymethyl)pyrrolidin-1-yl]-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-(hydroxymethyl)pyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-(hydroxymethyl)pyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157592555

Frequently Asked Questions

What is the IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide?
The IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide (CID 158065368) is N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide.
What is the SMILES notation for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide?
The canonical SMILES for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide is Cn1c(C#N)ccc1-c1cc(C(=O)Nc2ccc(OC(F)(F)Cl)cc2)cnc1N1CC[C@@H](O)C1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)[nH]1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)[nH]1.N#Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccc2N2CC[C@@H](O)C2)[nH]1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1.O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccc[nH]2)c1.
What is the InChIKey of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide?
The InChIKey is FLDSLPJKMUVNKT-ALLCUJASSA-N. The full InChI is InChI=1S/C23H20ClF2N5O3.C23H19F3N4O3.2C22H18ClF2N5O3.C21H19ClF2N4O3.C21H19F3N4O3.C21H19F3N4O2S/c1-30-16(11-27)4-7-20(30)19-10-14(12-28-21(19)31-9-8-17(32)13-31)22(33)29-15-2-5-18(6-3-15)34-23(24,25)26;24-23(25,26)33-18-5-2-15(3-6-18)29-22(32)14-1-8-21(30-10-9-17(31)13-30)19(11-14)20-7-4-16(12-27)28-20;2*23-22(24,25)33-17-4-1-14(2-5-17)29-21(32)13-9-18(19-6-3-15(10-26)28-19)20(27-11-13)30-8-7-16(31)12-30;3*22-21(23,24)31-16-5-3-14(4-6-16)27-20(30)13-10-17(18-2-1-8-25-18)19(26-11-13)28-9-7-15(29)12-28/h2-7,10,12,17,32H,8-9,13H2,1H3,(H,29,33);1-8,11,17,28,31H,9-10,13H2,(H,29,32);2*1-6,9,11,16,28,31H,7-8,12H2,(H,29,32);3*1-6,8,10-11,15,25,29H,7,9,12H2,(H,27,30)/t2*17-;2*16-;3*15-/m1111111/s1.
What are the key properties of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide?
N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide has a molecular weight of 3221.78 g/mol, XLogP of 28.48, 39 rotatable bonds, 20 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1-methylpyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;3-(5-cyano-1H-pyrrol-2-yl)-4-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide is sourced from PubChem (CID 158065368), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).