3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile

C98H56Cl2N44O2S — CID 158074351

IUPAC3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile
SMILESN#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2nnco2)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2nncs2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ccncn2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ccnnc2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ncccn2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2nnco2)nc1N
InChIInChI=1S/3C18H11N7.C16H9N7O.C14H7ClN8O.C14H7ClN8S/c19-10-14-17(20)25-16(18-22-7-2-8-23-18)15(24-14)12-4-5-13-11(9-12)3-1-6-21-13;19-9-15-18(20)25-17(13-5-7-22-23-10-13)16(24-15)12-3-4-14-11(8-12)2-1-6-21-14;19-9-15-18(20)25-17(14-5-7-21-10-23-14)16(24-15)12-3-4-13-11(8-12)2-1-6-22-13;17-7-12-15(18)22-14(16-23-20-8-24-16)13(21-12)10-3-4-11-9(6-10)2-1-5-19-11;2*15-8-2-6(1-7-4-18-22-10(7)8)11-12(14-23-19-5-24-14)21-13(17)9(3-16)20-11/h1-9H,(H2,20,25);2*1-8,10H,(H2,20,25);1-6,8H,(H2,18,22);2*1-2,4-5H,(H2,17,21)(H,18,22)
InChIKeyFMEMUKZBLOHJSQ-UHFFFAOYSA-N
MW1984.80 g/mol
LogP14.83
Rot. Bonds12

About 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile

3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile (PubChem CID 158074351) has the molecular formula C98H56Cl2N44O2S and a molecular weight of 1984.80 g/mol. Its IUPAC name is 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile.

Molecular Properties

Compound Name3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile
PubChem CID158074351
Molecular FormulaC98H56Cl2N44O2S
Molecular Weight1984.80 g/mol
Exact Mass1982.47
IUPAC Name3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile
SMILESN#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2nnco2)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2nncs2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ccncn2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ccnnc2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ncccn2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2nnco2)nc1N
InChIInChI=1S/3C18H11N7.C16H9N7O.C14H7ClN8O.C14H7ClN8S/c19-10-14-17(20)25-16(18-22-7-2-8-23-18)15(24-14)12-4-5-13-11(9-12)3-1-6-21-13;19-9-15-18(20)25-17(13-5-7-22-23-10-13)16(24-15)12-3-4-14-11(8-12)2-1-6-21-14;19-9-15-18(20)25-17(14-5-7-21-10-23-14)16(24-15)12-3-4-13-11(8-12)2-1-6-22-13;17-7-12-15(18)22-14(16-23-20-8-24-16)13(21-12)10-3-4-11-9(6-10)2-1-5-19-11;2*15-8-2-6(1-7-4-18-22-10(7)8)11-12(14-23-19-5-24-14)21-13(17)9(3-16)20-11/h1-9H,(H2,20,25);2*1-8,10H,(H2,20,25);1-6,8H,(H2,18,22);2*1-2,4-5H,(H2,17,21)(H,18,22)
InChIKeyFMEMUKZBLOHJSQ-UHFFFAOYSA-N
XLogP14.83
TPSA743.42 Ų
H-Bond Donors8
H-Bond Acceptors45
Rotatable Bonds12
Heavy Atoms147
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001984.80
LogP ≤ 514.83
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1045

Analyze 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile with MolForge

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Launch Full Analysis

Related Compounds

3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1H-imidazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,2-oxazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3-oxazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3-thiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(8-fluoroquinolin-6-yl)-5-(1H-1,2,4-triazol-5-yl)pyrazine-2-carbonitrile
CID 158522726
3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-dimethyl-1,2-oxazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-dimethyl-1,2-thiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methyl-1,2,4-thiadiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methyl-1,2-thiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-quinolin-6-yl-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile
CID 161415020
3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(2-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,2,4-oxadiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1H-pyrazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,2,4-thiadiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,2-thiazol-5-yl)pyrazine-2-carbonitrile
CID 161813029

Frequently Asked Questions

What is the IUPAC name of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile?
The IUPAC name of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile (CID 158074351) is 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile.
What is the SMILES notation for 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile?
The canonical SMILES for 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile is N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2nnco2)nc1N.N#Cc1nc(-c2cc(Cl)c3[nH]ncc3c2)c(-c2nncs2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ccncn2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ccnnc2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2ncccn2)nc1N.N#Cc1nc(-c2ccc3ncccc3c2)c(-c2nnco2)nc1N.
What is the InChIKey of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile?
The InChIKey is FMEMUKZBLOHJSQ-UHFFFAOYSA-N. The full InChI is InChI=1S/3C18H11N7.C16H9N7O.C14H7ClN8O.C14H7ClN8S/c19-10-14-17(20)25-16(18-22-7-2-8-23-18)15(24-14)12-4-5-13-11(9-12)3-1-6-21-13;19-9-15-18(20)25-17(13-5-7-22-23-10-13)16(24-15)12-3-4-14-11(8-12)2-1-6-21-14;19-9-15-18(20)25-17(14-5-7-21-10-23-14)16(24-15)12-3-4-13-11(8-12)2-1-6-22-13;17-7-12-15(18)22-14(16-23-20-8-24-16)13(21-12)10-3-4-11-9(6-10)2-1-5-19-11;2*15-8-2-6(1-7-4-18-22-10(7)8)11-12(14-23-19-5-24-14)21-13(17)9(3-16)20-11/h1-9H,(H2,20,25);2*1-8,10H,(H2,20,25);1-6,8H,(H2,18,22);2*1-2,4-5H,(H2,17,21)(H,18,22).
What are the key properties of 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile?
3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile has a molecular weight of 1984.80 g/mol, XLogP of 14.83, 12 rotatable bonds, 8 hydrogen bond donors, and 45 hydrogen bond acceptors.
Where does this data come from?
All data for 3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-oxadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile;3-amino-5-(1,3,4-oxadiazol-2-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyridazin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-2-yl-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-pyrimidin-4-yl-6-quinolin-6-ylpyrazine-2-carbonitrile is sourced from PubChem (CID 158074351), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).