N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide

C126H128N22O15S5 — CID 158080628

About N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide

N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide (PubChem CID 158080628) has the molecular formula C126H128N22O15S5 and a molecular weight of 2350.88 g/mol. Its IUPAC name is N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide.

Molecular Properties

• Compound Name: N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide
• PubChem CID: 158080628
• Molecular Formula: C126H128N22O15S5
• Molecular Weight: 2350.88 g/mol
• Exact Mass: 2348.85
• IUPAC Name: N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide
• SMILES: Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(-c5nccn5C)sc34)cc2n1C.Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(C(=O)N5CCC[C@H]5CO)sc34)cc2n1C.Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(C(=O)N5CC[C@@H](C)C5)sc34)cc2n1C.Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(C(=O)N5CC[C@@H](O)C5)sc34)cc2n1C.Cc1c(C(=O)NC2CC2)c2ccc(Oc3ccnc4cc(-c5nccn5C)sc34)cc2n1C
• InChI: InChI=1S/C26H28N4O4S.C26H28N4O3S.C25H23N5O2S.C25H26N4O4S.C24H23N5O2S/c1-15-23(26(33)28(2)3)18-8-7-17(12-20(18)29(15)4)34-21-9-10-27-19-13-22(35-24(19)21)25(32)30-11-5-6-16(30)14-31;1-15-9-11-30(14-15)25(31)22-13-19-24(34-22)21(8-10-27-19)33-17-6-7-18-20(12-17)29(5)16(2)23(18)26(32)28(3)4;1-14-22(25(31)28-15-4-5-15)17-7-6-16(12-19(17)30(14)3)32-20-8-9-26-18-13-21(33-23(18)20)24-27-10-11-29(24)2;1-14-22(25(32)27(2)3)17-6-5-16(11-19(17)28(14)4)33-20-7-9-26-18-12-21(34-23(18)20)24(31)29-10-8-15(30)13-29;1-14-21(24(30)27(2)3)16-7-6-15(12-18(16)29(14)5)31-19-8-9-25-17-13-20(32-22(17)19)23-26-10-11-28(23)4/h7-10,12-13,16,31H,5-6,11,14H2,1-4H3;6-8,10,12-13,15H,9,11,14H2,1-5H3;6-13,15H,4-5H2,1-3H3,(H,28,31);5-7,9,11-12,15,30H,8,10,13H2,1-4H3;6-13H,1-5H3/t16-;15-;;15-;/m01.1./s1
• InChIKey: FMXIGVUZMGUZEY-XXULXXRHSA-N
• XLogP: 23.23
• TPSA: 382.62 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 34
• Rotatable Bonds: 22
• Heavy Atoms: 168
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2350.88
LogP ≤ 5	23.23
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide?

The IUPAC name of N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide (CID 158080628) is N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide.

What is the SMILES notation for N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide?

The canonical SMILES for N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide is Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(-c5nccn5C)sc34)cc2n1C.Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(C(=O)N5CCC[C@H]5CO)sc34)cc2n1C.Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(C(=O)N5CC[C@@H](C)C5)sc34)cc2n1C.Cc1c(C(=O)N(C)C)c2ccc(Oc3ccnc4cc(C(=O)N5CC[C@@H](O)C5)sc34)cc2n1C.Cc1c(C(=O)NC2CC2)c2ccc(Oc3ccnc4cc(-c5nccn5C)sc34)cc2n1C.

What is the InChIKey of N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide?

The InChIKey is FMXIGVUZMGUZEY-XXULXXRHSA-N. The full InChI is InChI=1S/C26H28N4O4S.C26H28N4O3S.C25H23N5O2S.C25H26N4O4S.C24H23N5O2S/c1-15-23(26(33)28(2)3)18-8-7-17(12-20(18)29(15)4)34-21-9-10-27-19-13-22(35-24(19)21)25(32)30-11-5-6-16(30)14-31;1-15-9-11-30(14-15)25(31)22-13-19-24(34-22)21(8-10-27-19)33-17-6-7-18-20(12-17)29(5)16(2)23(18)26(32)28(3)4;1-14-22(25(31)28-15-4-5-15)17-7-6-16(12-19(17)30(14)3)32-20-8-9-26-18-13-21(33-23(18)20)24-27-10-11-29(24)2;1-14-22(25(32)27(2)3)17-6-5-16(11-19(17)28(14)4)33-20-7-9-26-18-12-21(34-23(18)20)24(31)29-10-8-15(30)13-29;1-14-21(24(30)27(2)3)16-7-6-15(12-18(16)29(14)5)31-19-8-9-25-17-13-20(32-22(17)19)23-26-10-11-28(23)4/h7-10,12-13,16,31H,5-6,11,14H2,1-4H3;6-8,10,12-13,15H,9,11,14H2,1-5H3;6-13,15H,4-5H2,1-3H3,(H,28,31);5-7,9,11-12,15,30H,8,10,13H2,1-4H3;6-13H,1-5H3/t16-;15-;;15-;/m01.1./s1.

What are the key properties of N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide?

N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide has a molecular weight of 2350.88 g/mol, XLogP of 23.23, 22 rotatable bonds, 3 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for N-cyclopropyl-1,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;6-[2-[(2S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;6-[2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-N,N,1,2-tetramethylindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide;N,N,1,2-tetramethyl-6-[2-[(3R)-3-methylpyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxyindole-3-carboxamide is sourced from PubChem (CID 158080628), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).