3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile

C108H74N38O3S3 — CID 158083277

IUPAC3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile
SMILESCc1cc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)on1.Cc1cc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)sn1.Cc1noc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)c1C.Cc1noc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)n1.Cc1nsc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)c1C.Cc1nsc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)n1
InChIInChI=1S/C19H14N6O.C19H14N6S.C18H12N6O.C18H12N6S.C17H11N7O.C17H11N7S/c2*1-10-11(2)25-26-18(10)17-16(23-15(9-20)19(21)24-17)13-5-6-14-12(8-13)4-3-7-22-14;2*1-10-7-15(25-24-10)17-16(22-14(9-19)18(20)23-17)12-4-5-13-11(8-12)3-2-6-21-13;2*1-9-21-17(25-24-9)15-14(22-13(8-18)16(19)23-15)11-4-5-12-10(7-11)3-2-6-20-12/h2*3-8H,1-2H3,(H2,21,24);2*2-8H,1H3,(H2,20,23);2*2-7H,1H3,(H2,19,23)
InChIKeyFNFCATGTESEPAI-UHFFFAOYSA-N
MW2048.24 g/mol
LogP19.47
Rot. Bonds12

About 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile

3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile (PubChem CID 158083277) has the molecular formula C108H74N38O3S3 and a molecular weight of 2048.24 g/mol. Its IUPAC name is 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile.

Molecular Properties

Compound Name3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile
PubChem CID158083277
Molecular FormulaC108H74N38O3S3
Molecular Weight2048.24 g/mol
Exact Mass2046.60
IUPAC Name3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile
SMILESCc1cc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)on1.Cc1cc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)sn1.Cc1noc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)c1C.Cc1noc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)n1.Cc1nsc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)c1C.Cc1nsc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)n1
InChIInChI=1S/C19H14N6O.C19H14N6S.C18H12N6O.C18H12N6S.C17H11N7O.C17H11N7S/c2*1-10-11(2)25-26-18(10)17-16(23-15(9-20)19(21)24-17)13-5-6-14-12(8-13)4-3-7-22-14;2*1-10-7-15(25-24-10)17-16(22-14(9-19)18(20)23-17)12-4-5-13-11(8-12)3-2-6-21-13;2*1-9-21-17(25-24-9)15-14(22-13(8-18)16(19)23-15)11-4-5-12-10(7-11)3-2-6-20-12/h2*3-8H,1-2H3,(H2,21,24);2*2-8H,1H3,(H2,20,23);2*2-7H,1H3,(H2,19,23)
InChIKeyFNFCATGTESEPAI-UHFFFAOYSA-N
XLogP19.47
TPSA673.42 Ų
H-Bond Donors6
H-Bond Acceptors44
Rotatable Bonds12
Heavy Atoms152
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002048.24
LogP ≤ 519.47
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1044

Analyze 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile with MolForge

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Launch Full Analysis

Related Compounds

3-amino-5-(1H-imidazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(1,3-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-6-quinolin-6-yl-5-(1,2-thiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-quinolin-6-yl-5-(1,3-thiazol-5-yl)pyrazine-2-carbonitrile
CID 159693097
3-amino-5-(2-methylpyrazol-3-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(1H-pyrazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-6-quinolin-6-yl-5-(1,2,4-thiadiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-quinolin-6-yl-5-(1H-1,2,4-triazol-5-yl)pyrazine-2-carbonitrile
CID 159742165
3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-dimethyl-1,2-oxazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3,4-dimethyl-1,2-thiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methyl-1,2,4-thiadiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-(7-chloro-1H-indazol-5-yl)-5-(3-methyl-1,2-thiazol-5-yl)pyrazine-2-carbonitrile;3-amino-6-quinolin-6-yl-5-(1,3,4-thiadiazol-2-yl)pyrazine-2-carbonitrile
CID 161415020

Frequently Asked Questions

What is the IUPAC name of 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile?
The IUPAC name of 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile (CID 158083277) is 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile.
What is the SMILES notation for 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile?
The canonical SMILES for 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile is Cc1cc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)on1.Cc1cc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)sn1.Cc1noc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)c1C.Cc1noc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)n1.Cc1nsc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)c1C.Cc1nsc(-c2nc(N)c(C#N)nc2-c2ccc3ncccc3c2)n1.
What is the InChIKey of 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile?
The InChIKey is FNFCATGTESEPAI-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H14N6O.C19H14N6S.C18H12N6O.C18H12N6S.C17H11N7O.C17H11N7S/c2*1-10-11(2)25-26-18(10)17-16(23-15(9-20)19(21)24-17)13-5-6-14-12(8-13)4-3-7-22-14;2*1-10-7-15(25-24-10)17-16(22-14(9-19)18(20)23-17)12-4-5-13-11(8-12)3-2-6-21-13;2*1-9-21-17(25-24-9)15-14(22-13(8-18)16(19)23-15)11-4-5-12-10(7-11)3-2-6-20-12/h2*3-8H,1-2H3,(H2,21,24);2*2-8H,1H3,(H2,20,23);2*2-7H,1H3,(H2,19,23).
What are the key properties of 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile?
3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile has a molecular weight of 2048.24 g/mol, XLogP of 19.47, 12 rotatable bonds, 6 hydrogen bond donors, and 44 hydrogen bond acceptors.
Where does this data come from?
All data for 3-amino-5-(3,4-dimethyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3,4-dimethyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-oxazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2,4-thiadiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile;3-amino-5-(3-methyl-1,2-thiazol-5-yl)-6-quinolin-6-ylpyrazine-2-carbonitrile is sourced from PubChem (CID 158083277), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).