7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide

C125H138F7N25O5S5 — CID 158087803

About 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide

7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide (PubChem CID 158087803) has the molecular formula C125H138F7N25O5S5 and a molecular weight of 2363.97 g/mol. Its IUPAC name is 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide.

Molecular Properties

• Compound Name: 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide
• PubChem CID: 158087803
• Molecular Formula: C125H138F7N25O5S5
• Molecular Weight: 2363.97 g/mol
• Exact Mass: 2361.98
• IUPAC Name: 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide
• SMILES: Cc1cnc2c(N)c(C(=O)NC[C@@H](C)c3cc(F)c(N4CC5CC6CCC65C4)cc3F)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@@H](C)c3ccc(N4CC5CC6CCC65C4)c(F)c3)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@@H](C)c3ccc(N4CC5CC6CCC65C4)cc3F)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@H](C)c3cc(F)c(N4CC5CC6CCC65C4)cc3F)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@H](C)c3ccc(N4CC5CC6CCC65C4)c(F)c3)sc2n1
• InChI: InChI=1S/2C25H27F2N5OS.3C25H28FN5OS/c2*1-12(8-30-23(33)22-20(28)21-24(34-22)31-13(2)9-29-21)16-6-18(27)19(7-17(16)26)32-10-15-5-14-3-4-25(14,15)11-32;1-13(9-29-23(32)22-20(27)21-24(33-22)30-14(2)10-28-21)18-4-3-17(8-19(18)26)31-11-16-7-15-5-6-25(15,16)12-31;2*1-13(9-29-23(32)22-20(27)21-24(33-22)30-14(2)10-28-21)15-3-4-19(18(26)7-15)31-11-17-8-16-5-6-25(16,17)12-31/h2*6-7,9,12,14-15H,3-5,8,10-11,28H2,1-2H3,(H,30,33);3-4,8,10,13,15-16H,5-7,9,11-12,27H2,1-2H3,(H,29,32);2*3-4,7,10,13,16-17H,5-6,8-9,11-12,27H2,1-2H3,(H,29,32)/t2*12-,14?,15?,25?;13-,15?,16?,25?;2*13-,16?,17?,25?/m10110/s1
• InChIKey: FNSNLMTZKWZSNW-IMSWWKDMSA-N
• XLogP: 22.73
• TPSA: 420.70 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 30
• Rotatable Bonds: 25
• Heavy Atoms: 167
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2363.97
LogP ≤ 5	22.73
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide?

The IUPAC name of 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide (CID 158087803) is 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide.

What is the SMILES notation for 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide?

The canonical SMILES for 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide is Cc1cnc2c(N)c(C(=O)NC[C@@H](C)c3cc(F)c(N4CC5CC6CCC65C4)cc3F)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@@H](C)c3ccc(N4CC5CC6CCC65C4)c(F)c3)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@@H](C)c3ccc(N4CC5CC6CCC65C4)cc3F)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@H](C)c3cc(F)c(N4CC5CC6CCC65C4)cc3F)sc2n1.Cc1cnc2c(N)c(C(=O)NC[C@H](C)c3ccc(N4CC5CC6CCC65C4)c(F)c3)sc2n1.

What is the InChIKey of 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide?

The InChIKey is FNSNLMTZKWZSNW-IMSWWKDMSA-N. The full InChI is InChI=1S/2C25H27F2N5OS.3C25H28FN5OS/c2*1-12(8-30-23(33)22-20(28)21-24(34-22)31-13(2)9-29-21)16-6-18(27)19(7-17(16)26)32-10-15-5-14-3-4-25(14,15)11-32;1-13(9-29-23(32)22-20(27)21-24(33-22)30-14(2)10-28-21)18-4-3-17(8-19(18)26)31-11-16-7-15-5-6-25(15,16)12-31;2*1-13(9-29-23(32)22-20(27)21-24(33-22)30-14(2)10-28-21)15-3-4-19(18(26)7-15)31-11-17-8-16-5-6-25(16,17)12-31/h2*6-7,9,12,14-15H,3-5,8,10-11,28H2,1-2H3,(H,30,33);3-4,8,10,13,15-16H,5-7,9,11-12,27H2,1-2H3,(H,29,32);2*3-4,7,10,13,16-17H,5-6,8-9,11-12,27H2,1-2H3,(H,29,32)/t2*12-,14?,15?,25?;13-,15?,16?,25?;2*13-,16?,17?,25?/m10110/s1.

What are the key properties of 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide?

7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide has a molecular weight of 2363.97 g/mol, XLogP of 22.73, 25 rotatable bonds, 10 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2,5-difluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-2-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2S)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide;7-amino-N-[(2R)-2-[4-(8-azatricyclo[4.3.0.01,4]nonan-8-yl)-3-fluorophenyl]propyl]-3-methylthieno[2,3-b]pyrazine-6-carboxamide is sourced from PubChem (CID 158087803), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).