5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one

C119H134F25N23O7S2 — CID 158091503

IUPAC5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one
SMILESCC(=O)Cc1ccc(CN2CCc3c2ncnc3N2CCCC2c2ccc(C(F)(F)F)cc2)cc1.CC(=O)N1CCC(F)(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1.CS(=O)(=O)N1CCC(F)(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1.Fc1c(NCC2(F)CCOCC2)ncnc1N1CCCCC1c1ccc(C(F)(F)F)cc1.O=S(=O)(N1CCC(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1)C(F)(F)F
InChIInChI=1S/C27H27F3N4O.C24H28F5N5O.C23H26F7N5O2S.C23H28F5N5O2S.C22H25F5N4O/c1-18(35)15-19-4-6-20(7-5-19)16-33-14-12-23-25(33)31-17-32-26(23)34-13-2-3-24(34)21-8-10-22(11-9-21)27(28,29)30;1-16(35)33-12-9-23(26,10-13-33)14-30-21-20(25)22(32-15-31-21)34-11-3-2-4-19(34)17-5-7-18(8-6-17)24(27,28)29;24-19-20(31-13-15-8-11-34(12-9-15)38(36,37)23(28,29)30)32-14-33-21(19)35-10-2-1-3-18(35)16-4-6-17(7-5-16)22(25,26)27;1-36(34,35)32-12-9-22(25,10-13-32)14-29-20-19(24)21(31-15-30-20)33-11-3-2-4-18(33)16-5-7-17(8-6-16)23(26,27)28;23-18-19(28-13-21(24)8-11-32-12-9-21)29-14-30-20(18)31-10-2-1-3-17(31)15-4-6-16(7-5-15)22(25,26)27/h4-11,17,24H,2-3,12-16H2,1H3;5-8,15,19H,2-4,9-14H2,1H3,(H,30,31,32);4-7,14-15,18H,1-3,8-13H2,(H,31,32,33);5-8,15,18H,2-4,9-14H2,1H3,(H,29,30,31);4-7,14,17H,1-3,8-13H2,(H,28,29,30)
InChIKeyFODRLMNUYGMCCF-UHFFFAOYSA-N
MW2537.62 g/mol
LogP25.84
Rot. Bonds28

About 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one

5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one (PubChem CID 158091503) has the molecular formula C119H134F25N23O7S2 and a molecular weight of 2537.62 g/mol. Its IUPAC name is 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one.

Molecular Properties

Compound Name5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one
PubChem CID158091503
Molecular FormulaC119H134F25N23O7S2
Molecular Weight2537.62 g/mol
Exact Mass2535.99
IUPAC Name5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one
SMILESCC(=O)Cc1ccc(CN2CCc3c2ncnc3N2CCCC2c2ccc(C(F)(F)F)cc2)cc1.CC(=O)N1CCC(F)(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1.CS(=O)(=O)N1CCC(F)(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1.Fc1c(NCC2(F)CCOCC2)ncnc1N1CCCCC1c1ccc(C(F)(F)F)cc1.O=S(=O)(N1CCC(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1)C(F)(F)F
InChIInChI=1S/C27H27F3N4O.C24H28F5N5O.C23H26F7N5O2S.C23H28F5N5O2S.C22H25F5N4O/c1-18(35)15-19-4-6-20(7-5-19)16-33-14-12-23-25(33)31-17-32-26(23)34-13-2-3-24(34)21-8-10-22(11-9-21)27(28,29)30;1-16(35)33-12-9-23(26,10-13-33)14-30-21-20(25)22(32-15-31-21)34-11-3-2-4-19(34)17-5-7-18(8-6-17)24(27,28)29;24-19-20(31-13-15-8-11-34(12-9-15)38(36,37)23(28,29)30)32-14-33-21(19)35-10-2-1-3-18(35)16-4-6-17(7-5-16)22(25,26)27;1-36(34,35)32-12-9-22(25,10-13-32)14-29-20-19(24)21(31-15-30-20)33-11-3-2-4-18(33)16-5-7-17(8-6-16)23(26,27)28;23-18-19(28-13-21(24)8-11-32-12-9-21)29-14-30-20(18)31-10-2-1-3-17(31)15-4-6-16(7-5-15)22(25,26)27/h4-11,17,24H,2-3,12-16H2,1H3;5-8,15,19H,2-4,9-14H2,1H3,(H,30,31,32);4-7,14-15,18H,1-3,8-13H2,(H,31,32,33);5-8,15,18H,2-4,9-14H2,1H3,(H,29,30,31);4-7,14,17H,1-3,8-13H2,(H,28,29,30)
InChIKeyFODRLMNUYGMCCF-UHFFFAOYSA-N
XLogP25.84
TPSA317.83 Ų
H-Bond Donors4
H-Bond Acceptors27
Rotatable Bonds28
Heavy Atoms176
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002537.62
LogP ≤ 525.84
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1027

Analyze 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one with MolForge

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Related Compounds

2-[4-[[[6-[cyclopropyl-[cyclopropyl-[4-(trifluoromethyl)phenyl]methyl]amino]-5-fluoropyrimidin-4-yl]amino]methyl]phenyl]acetamide;2-[4-[[[6-[cyclopropyl-[[4-(1,1-difluoroethyl)phenyl]methyl]amino]-5-fluoropyrimidin-4-yl]amino]methyl]phenyl]acetonitrile;1-[4-[[[6-[cyclopropyl-[[4-(1,1-difluoroethyl)phenyl]methyl]amino]-5-fluoropyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;4-N-cyclopropyl-4-N-[[4-(1,1-difluoroethyl)phenyl]methyl]-5-fluoro-6-N-(oxan-4-ylmethyl)pyrimidine-4,6-diamine
CID 158436657
5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine
CID 158577919

Frequently Asked Questions

What is the IUPAC name of 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one?
The IUPAC name of 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one (CID 158091503) is 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one.
What is the SMILES notation for 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one?
The canonical SMILES for 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one is CC(=O)Cc1ccc(CN2CCc3c2ncnc3N2CCCC2c2ccc(C(F)(F)F)cc2)cc1.CC(=O)N1CCC(F)(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1.CS(=O)(=O)N1CCC(F)(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1.Fc1c(NCC2(F)CCOCC2)ncnc1N1CCCCC1c1ccc(C(F)(F)F)cc1.O=S(=O)(N1CCC(CNc2ncnc(N3CCCCC3c3ccc(C(F)(F)F)cc3)c2F)CC1)C(F)(F)F.
What is the InChIKey of 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one?
The InChIKey is FODRLMNUYGMCCF-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H27F3N4O.C24H28F5N5O.C23H26F7N5O2S.C23H28F5N5O2S.C22H25F5N4O/c1-18(35)15-19-4-6-20(7-5-19)16-33-14-12-23-25(33)31-17-32-26(23)34-13-2-3-24(34)21-8-10-22(11-9-21)27(28,29)30;1-16(35)33-12-9-23(26,10-13-33)14-30-21-20(25)22(32-15-31-21)34-11-3-2-4-19(34)17-5-7-18(8-6-17)24(27,28)29;24-19-20(31-13-15-8-11-34(12-9-15)38(36,37)23(28,29)30)32-14-33-21(19)35-10-2-1-3-18(35)16-4-6-17(7-5-16)22(25,26)27;1-36(34,35)32-12-9-22(25,10-13-32)14-29-20-19(24)21(31-15-30-20)33-11-3-2-4-18(33)16-5-7-17(8-6-16)23(26,27)28;23-18-19(28-13-21(24)8-11-32-12-9-21)29-14-30-20(18)31-10-2-1-3-17(31)15-4-6-16(7-5-15)22(25,26)27/h4-11,17,24H,2-3,12-16H2,1H3;5-8,15,19H,2-4,9-14H2,1H3,(H,30,31,32);4-7,14-15,18H,1-3,8-13H2,(H,31,32,33);5-8,15,18H,2-4,9-14H2,1H3,(H,29,30,31);4-7,14,17H,1-3,8-13H2,(H,28,29,30).
What are the key properties of 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one?
5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one has a molecular weight of 2537.62 g/mol, XLogP of 25.84, 28 rotatable bonds, 4 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for 5-fluoro-N-[(4-fluoro-1-methylsulfonylpiperidin-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;5-fluoro-N-[(4-fluorooxan-4-yl)methyl]-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-amine;1-[4-fluoro-4-[[[5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidin-4-yl]amino]methyl]piperidin-1-yl]ethanone;5-fluoro-6-[2-[4-(trifluoromethyl)phenyl]piperidin-1-yl]-N-[[1-(trifluoromethylsulfonyl)piperidin-4-yl]methyl]pyrimidin-4-amine;1-[4-[[4-[2-[4-(trifluoromethyl)phenyl]pyrrolidin-1-yl]-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]methyl]phenyl]propan-2-one is sourced from PubChem (CID 158091503), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).