N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide

C110H128F5N17O15S4 — CID 158094521

About N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide

N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide (PubChem CID 158094521) has the molecular formula C110H128F5N17O15S4 and a molecular weight of 2151.60 g/mol. Its IUPAC name is N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide
• PubChem CID: 158094521
• Molecular Formula: C110H128F5N17O15S4
• Molecular Weight: 2151.60 g/mol
• Exact Mass: 2149.86
• IUPAC Name: N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide
• SMILES: CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CC(C(F)(F)F)CCC3C)n2)c1.CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3ccccn3)c(N3C[C@@H](C)CC3(C)C)n2)c1.CC1CC(c2ncccc2C(=O)NS(=O)(=O)c2cccc(N3CCC4=C(Cc5ccccc54)C3)n2)C(C)(C)C1.CC1CN(c2ncccc2C(=O)NS(=O)(=O)c2cccc(OC3CCCC3)n2)C(C)(C)C1
• InChI: InChI=1S/C31H34N4O3S.C28H31F4N5O4S.C28H33FN4O4S.C23H30N4O4S/c1-20-16-26(31(2,3)18-20)29-25(10-7-14-32-29)30(36)34-39(37,38)28-12-6-11-27(33-28)35-15-13-24-22(19-35)17-21-8-4-5-9-23(21)24;1-16(2)15-41-21-12-18(11-20(29)13-21)23-10-9-22(27(38)36-42(39,40)25-6-4-5-24(33)35-25)26(34-23)37-14-19(28(30,31)32)8-7-17(37)3;1-18(2)17-37-22-13-20(12-21(29)14-22)24-10-9-23(26(31-24)33-16-19(3)15-28(33,4)5)27(34)32-38(35,36)25-8-6-7-11-30-25;1-16-14-23(2,3)27(15-16)21-18(10-7-13-24-21)22(28)26-32(29,30)20-12-6-11-19(25-20)31-17-8-4-5-9-17/h4-12,14,20,26H,13,15-19H2,1-3H3,(H,34,36);4-6,9-13,16-17,19H,7-8,14-15H2,1-3H3,(H2,33,35)(H,36,38);6-14,18-19H,15-17H2,1-5H3,(H,32,34);6-7,10-13,16-17H,4-5,8-9,14-15H2,1-3H3,(H,26,28)/t;;19-;/m..0./s1
• InChIKey: FOMWBAQWWSUUBW-KJFDLJPKSA-N
• XLogP: 19.14
• TPSA: 422.75 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 28
• Rotatable Bonds: 27
• Heavy Atoms: 151
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2151.60
LogP ≤ 5	19.14
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	28

Frequently Asked Questions

What is the IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide?

The IUPAC name of N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide (CID 158094521) is N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide.

What is the SMILES notation for N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide?

The canonical SMILES for N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide is CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3cccc(N)n3)c(N3CC(C(F)(F)F)CCC3C)n2)c1.CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3ccccn3)c(N3C[C@@H](C)CC3(C)C)n2)c1.CC1CC(c2ncccc2C(=O)NS(=O)(=O)c2cccc(N3CCC4=C(Cc5ccccc54)C3)n2)C(C)(C)C1.CC1CN(c2ncccc2C(=O)NS(=O)(=O)c2cccc(OC3CCCC3)n2)C(C)(C)C1.

What is the InChIKey of N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide?

The InChIKey is FOMWBAQWWSUUBW-KJFDLJPKSA-N. The full InChI is InChI=1S/C31H34N4O3S.C28H31F4N5O4S.C28H33FN4O4S.C23H30N4O4S/c1-20-16-26(31(2,3)18-20)29-25(10-7-14-32-29)30(36)34-39(37,38)28-12-6-11-27(33-28)35-15-13-24-22(19-35)17-21-8-4-5-9-23(21)24;1-16(2)15-41-21-12-18(11-20(29)13-21)23-10-9-22(27(38)36-42(39,40)25-6-4-5-24(33)35-25)26(34-23)37-14-19(28(30,31)32)8-7-17(37)3;1-18(2)17-37-22-13-20(12-21(29)14-22)24-10-9-23(26(31-24)33-16-19(3)15-28(33,4)5)27(34)32-38(35,36)25-8-6-7-11-30-25;1-16-14-23(2,3)27(15-16)21-18(10-7-13-24-21)22(28)26-32(29,30)20-12-6-11-19(25-20)31-17-8-4-5-9-17/h4-12,14,20,26H,13,15-19H2,1-3H3,(H,34,36);4-6,9-13,16-17,19H,7-8,14-15H2,1-3H3,(H2,33,35)(H,36,38);6-14,18-19H,15-17H2,1-5H3,(H,32,34);6-7,10-13,16-17H,4-5,8-9,14-15H2,1-3H3,(H,26,28)/t;;19-;/m..0./s1.

What are the key properties of N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide?

N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide has a molecular weight of 2151.60 g/mol, XLogP of 19.14, 27 rotatable bonds, 5 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(6-amino-2-pyridinyl)sulfonyl]-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[2-methyl-5-(trifluoromethyl)piperidin-1-yl]pyridine-3-carboxamide;N-[(6-cyclopentyloxy-2-pyridinyl)sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-pyridin-2-ylsulfonyl-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(1,3,4,9-tetrahydroindeno[2,1-c]pyridin-2-yl)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylcyclopentyl)pyridine-3-carboxamide is sourced from PubChem (CID 158094521), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).