(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane

C133H138F6N26O10 — CID 158110653

About (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane

(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane (PubChem CID 158110653) has the molecular formula C133H138F6N26O10 and a molecular weight of 2374.73 g/mol. Its IUPAC name is (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane.

Molecular Properties

• Compound Name: (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane
• PubChem CID: 158110653
• Molecular Formula: C133H138F6N26O10
• Molecular Weight: 2374.73 g/mol
• Exact Mass: 2373.10
• IUPAC Name: (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane
• SMILES: C.C[C@@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5=CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.C[C@@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.C[C@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5=CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.[C-]#[N+]c1cc2c(-c3nc(C4CCOCC4)n4c3CN(C)C(=O)[C@@H]4C)cccc2nc1-c1cnn(C)c1.[C-]#[N+]c1cc2c(-c3nc(C4CCOCC4)n4c3CN(C)C(=O)[C@H]4C)cccc2nc1-c1cnn(C)c1
• InChI: InChI=1S/2C27H27N7O2.C26H28F2N4O2.2C26H26F2N4O2.CH4/c2*1-16-27(35)32(3)15-23-25(31-26(34(16)23)17-8-10-36-11-9-17)19-6-5-7-21-20(19)12-22(28-2)24(30-21)18-13-29-33(4)14-18;3*1-14-26(33)31(2)13-21-23(30-25(32(14)21)16-6-7-16)17-4-3-5-20-18(17)12-19(24(27)28)22(29-20)15-8-10-34-11-9-15;/h2*5-7,12-14,16-17H,8-11,15H2,1,3-4H3;3-5,12,14-16,24H,6-11,13H2,1-2H3;2*3-5,8,12,14,16,24H,6-7,9-11,13H2,1-2H3;1H4/t2*16-;3*14-;/m10110./s1
• InChIKey: FQJSBISANYIRIC-LSPNTJFJSA-N
• XLogP: 25.43
• TPSA: 345.61 Ų
• H-Bond Acceptors: 29
• Rotatable Bonds: 18
• Heavy Atoms: 175
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2374.73
LogP ≤ 5	25.43
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane?

The IUPAC name of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane (CID 158110653) is (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane.

What is the SMILES notation for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane?

The canonical SMILES for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane is C.C[C@@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5=CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.C[C@@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.C[C@H]1C(=O)N(C)Cc2c(-c3cccc4nc(C5=CCOCC5)c(C(F)F)cc34)nc(C3CC3)n21.[C-]#[N+]c1cc2c(-c3nc(C4CCOCC4)n4c3CN(C)C(=O)[C@@H]4C)cccc2nc1-c1cnn(C)c1.[C-]#[N+]c1cc2c(-c3nc(C4CCOCC4)n4c3CN(C)C(=O)[C@H]4C)cccc2nc1-c1cnn(C)c1.

What is the InChIKey of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane?

The InChIKey is FQJSBISANYIRIC-LSPNTJFJSA-N. The full InChI is InChI=1S/2C27H27N7O2.C26H28F2N4O2.2C26H26F2N4O2.CH4/c2*1-16-27(35)32(3)15-23-25(31-26(34(16)23)17-8-10-36-11-9-17)19-6-5-7-21-20(19)12-22(28-2)24(30-21)18-13-29-33(4)14-18;3*1-14-26(33)31(2)13-21-23(30-25(32(14)21)16-6-7-16)17-4-3-5-20-18(17)12-19(24(27)28)22(29-20)15-8-10-34-11-9-15;/h2*5-7,12-14,16-17H,8-11,15H2,1,3-4H3;3-5,12,14-16,24H,6-11,13H2,1-2H3;2*3-5,8,12,14,16,24H,6-7,9-11,13H2,1-2H3;1H4/t2*16-;3*14-;/m10110./s1.

What are the key properties of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane?

(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane has a molecular weight of 2374.73 g/mol, XLogP of 25.43, 18 rotatable bonds, 0 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(3,6-dihydro-2H-pyran-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(oxan-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-1-[3-isocyano-2-(1-methylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-3-(oxan-4-yl)-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;methane is sourced from PubChem (CID 158110653), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).