N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide

C122H119BrF7N29O11S2 — CID 158114166

About N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide

N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide (PubChem CID 158114166) has the molecular formula C122H119BrF7N29O11S2 and a molecular weight of 2444.51 g/mol. Its IUPAC name is N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide.

Molecular Properties

• Compound Name: N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide
• PubChem CID: 158114166
• Molecular Formula: C122H119BrF7N29O11S2
• Molecular Weight: 2444.51 g/mol
• Exact Mass: 2441.82
• IUPAC Name: N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide
• SMILES: CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(N2CCC(F)(F)CC2)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(N2CCC(S(C)(=O)=O)CC2)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(N2CCN(C)CC2)c1.COC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(Br)c1.COC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1
• InChI: InChI=1S/C27H29FN6O3S.C26H25F3N6O.C26H28FN7O.C22H20FN5O4S.C21H17BrFN5O2/c1-3-24(18-8-11-30-26(14-18)33-12-9-21(10-13-33)38(2,36)37)32-27(35)23-15-29-17-25-22(23)16-31-34(25)20-6-4-19(28)5-7-20;1-2-22(17-7-10-31-24(13-17)34-11-8-26(28,29)9-12-34)33-25(36)21-14-30-16-23-20(21)15-32-35(23)19-5-3-18(27)4-6-19;1-3-23(18-8-9-29-25(14-18)33-12-10-32(2)11-13-33)31-26(35)22-15-28-17-24-21(22)16-30-34(24)20-6-4-19(27)5-7-20;1-32-13-19(14-7-8-25-21(9-14)33(2,30)31)27-22(29)18-10-24-12-20-17(18)11-26-28(20)16-5-3-15(23)4-6-16;1-30-12-18(13-6-7-25-20(22)8-13)27-21(29)17-9-24-11-19-16(17)10-26-28(19)15-4-2-14(23)3-5-15/h4-8,11,14-17,21,24H,3,9-10,12-13H2,1-2H3,(H,32,35);3-7,10,13-16,22H,2,8-9,11-12H2,1H3,(H,33,36);4-9,14-17,23H,3,10-13H2,1-2H3,(H,31,35);3-12,19H,13H2,1-2H3,(H,27,29);2-11,18H,12H2,1H3,(H,27,29)/t24-;22-;23-;19-;18-/m00000/s1
• InChIKey: FQUIHSNZOUXWFU-IDSYANIWSA-N
• XLogP: 18.82
• TPSA: 463.20 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 35
• Rotatable Bonds: 32
• Heavy Atoms: 172
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2444.51
LogP ≤ 5	18.82
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	35

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The IUPAC name of N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide (CID 158114166) is N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide.

What is the SMILES notation for N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The canonical SMILES for N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide is CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(N2CCC(F)(F)CC2)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(N2CCC(S(C)(=O)=O)CC2)c1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(N2CCN(C)CC2)c1.COC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(Br)c1.COC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1.

What is the InChIKey of N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The InChIKey is FQUIHSNZOUXWFU-IDSYANIWSA-N. The full InChI is InChI=1S/C27H29FN6O3S.C26H25F3N6O.C26H28FN7O.C22H20FN5O4S.C21H17BrFN5O2/c1-3-24(18-8-11-30-26(14-18)33-12-9-21(10-13-33)38(2,36)37)32-27(35)23-15-29-17-25-22(23)16-31-34(25)20-6-4-19(28)5-7-20;1-2-22(17-7-10-31-24(13-17)34-11-8-26(28,29)9-12-34)33-25(36)21-14-30-16-23-20(21)15-32-35(23)19-5-3-18(27)4-6-19;1-3-23(18-8-9-29-25(14-18)33-12-10-32(2)11-13-33)31-26(35)22-15-28-17-24-21(22)16-30-34(24)20-6-4-19(27)5-7-20;1-32-13-19(14-7-8-25-21(9-14)33(2,30)31)27-22(29)18-10-24-12-20-17(18)11-26-28(20)16-5-3-15(23)4-6-16;1-30-12-18(13-6-7-25-20(22)8-13)27-21(29)17-9-24-11-19-16(17)10-26-28(19)15-4-2-14(23)3-5-15/h4-8,11,14-17,21,24H,3,9-10,12-13H2,1-2H3,(H,32,35);3-7,10,13-16,22H,2,8-9,11-12H2,1H3,(H,33,36);4-9,14-17,23H,3,10-13H2,1-2H3,(H,31,35);3-12,19H,13H2,1-2H3,(H,27,29);2-11,18H,12H2,1H3,(H,27,29)/t24-;22-;23-;19-;18-/m00000/s1.

What are the key properties of N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide has a molecular weight of 2444.51 g/mol, XLogP of 18.82, 32 rotatable bonds, 5 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1R)-1-(2-bromo-4-pyridinyl)-2-methoxyethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(4,4-difluoropiperidin-1-yl)-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-methoxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-[2-(4-methylsulfonylpiperidin-1-yl)-4-pyridinyl]propyl]pyrazolo[5,4-c]pyridine-4-carboxamide is sourced from PubChem (CID 158114166), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).