N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide

C127H99Cl5FN29O6 — CID 158123130

IUPACN-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide
SMILESCN1CCC(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)C1.CN1CCC(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)CC1=O.Cn1ccc(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)c1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1NC(=O)c1ccc(F)cc1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1NC(=O)c1cccnc1
InChIInChI=1S/C26H17ClFN5O.C26H23ClN6O2.C25H23ClN6O.C25H19ClN6O.C25H17ClN6O/c27-20-14-18(13-17-7-4-12-30-21(17)20)23-22(15-5-2-1-3-6-15)31-24(29)25(32-23)33-26(34)16-8-10-19(28)11-9-16;1-33-11-9-17(14-20(33)34)26(35)32-25-24(28)30-22(15-6-3-2-4-7-15)23(31-25)18-12-16-8-5-10-29-21(16)19(27)13-18;2*1-32-11-9-17(14-32)25(33)31-24-23(27)29-21(15-6-3-2-4-7-15)22(30-24)18-12-16-8-5-10-28-20(16)19(26)13-18;26-19-13-18(12-16-8-5-11-29-20(16)19)22-21(15-6-2-1-3-7-15)30-23(27)24(31-22)32-25(33)17-9-4-10-28-14-17/h1-14H,(H2,29,31)(H,32,33,34);2-8,10,12-13,17H,9,11,14H2,1H3,(H2,28,30)(H,31,32,35);2-8,10,12-13,17H,9,11,14H2,1H3,(H2,27,29)(H,30,31,33);2-14H,1H3,(H2,27,29)(H,30,31,33);1-14H,(H2,27,30)(H,31,32,33)
InChIKeyFRVLWTMMWCAWPP-UHFFFAOYSA-N
MW2323.65 g/mol
LogP25.30
Rot. Bonds20

About N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide

N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide (PubChem CID 158123130) has the molecular formula C127H99Cl5FN29O6 and a molecular weight of 2323.65 g/mol. Its IUPAC name is N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide
PubChem CID158123130
Molecular FormulaC127H99Cl5FN29O6
Molecular Weight2323.65 g/mol
Exact Mass2319.68
IUPAC NameN-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide
SMILESCN1CCC(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)C1.CN1CCC(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)CC1=O.Cn1ccc(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)c1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1NC(=O)c1ccc(F)cc1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1NC(=O)c1cccnc1
InChIInChI=1S/C26H17ClFN5O.C26H23ClN6O2.C25H23ClN6O.C25H19ClN6O.C25H17ClN6O/c27-20-14-18(13-17-7-4-12-30-21(17)20)23-22(15-5-2-1-3-6-15)31-24(29)25(32-23)33-26(34)16-8-10-19(28)11-9-16;1-33-11-9-17(14-20(33)34)26(35)32-25-24(28)30-22(15-6-3-2-4-7-15)23(31-25)18-12-16-8-5-10-29-21(16)19(27)13-18;2*1-32-11-9-17(14-32)25(33)31-24-23(27)29-21(15-6-3-2-4-7-15)22(30-24)18-12-16-8-5-10-28-20(16)19(26)13-18;26-19-13-18(12-16-8-5-11-29-20(16)19)22-21(15-6-2-1-3-7-15)30-23(27)24(31-22)32-25(33)17-9-4-10-28-14-17/h1-14H,(H2,29,31)(H,32,33,34);2-8,10,12-13,17H,9,11,14H2,1H3,(H2,28,30)(H,31,32,35);2-8,10,12-13,17H,9,11,14H2,1H3,(H2,27,29)(H,30,31,33);2-14H,1H3,(H2,27,29)(H,30,31,33);1-14H,(H2,27,30)(H,31,32,33)
InChIKeyFRVLWTMMWCAWPP-UHFFFAOYSA-N
XLogP25.30
TPSA510.32 Ų
H-Bond Donors10
H-Bond Acceptors29
Rotatable Bonds20
Heavy Atoms168
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002323.65
LogP ≤ 525.30
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1029

Analyze N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide?
The IUPAC name of N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide (CID 158123130) is N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide.
What is the SMILES notation for N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide?
The canonical SMILES for N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide is CN1CCC(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)C1.CN1CCC(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)CC1=O.Cn1ccc(C(=O)Nc2nc(-c3cc(Cl)c4ncccc4c3)c(-c3ccccc3)nc2N)c1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1NC(=O)c1ccc(F)cc1.Nc1nc(-c2ccccc2)c(-c2cc(Cl)c3ncccc3c2)nc1NC(=O)c1cccnc1.
What is the InChIKey of N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide?
The InChIKey is FRVLWTMMWCAWPP-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H17ClFN5O.C26H23ClN6O2.C25H23ClN6O.C25H19ClN6O.C25H17ClN6O/c27-20-14-18(13-17-7-4-12-30-21(17)20)23-22(15-5-2-1-3-6-15)31-24(29)25(32-23)33-26(34)16-8-10-19(28)11-9-16;1-33-11-9-17(14-20(33)34)26(35)32-25-24(28)30-22(15-6-3-2-4-7-15)23(31-25)18-12-16-8-5-10-29-21(16)19(27)13-18;2*1-32-11-9-17(14-32)25(33)31-24-23(27)29-21(15-6-3-2-4-7-15)22(30-24)18-12-16-8-5-10-28-20(16)19(26)13-18;26-19-13-18(12-16-8-5-11-29-20(16)19)22-21(15-6-2-1-3-7-15)30-23(27)24(31-22)32-25(33)17-9-4-10-28-14-17/h1-14H,(H2,29,31)(H,32,33,34);2-8,10,12-13,17H,9,11,14H2,1H3,(H2,28,30)(H,31,32,35);2-8,10,12-13,17H,9,11,14H2,1H3,(H2,27,29)(H,30,31,33);2-14H,1H3,(H2,27,29)(H,30,31,33);1-14H,(H2,27,30)(H,31,32,33).
What are the key properties of N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide?
N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide has a molecular weight of 2323.65 g/mol, XLogP of 25.30, 20 rotatable bonds, 10 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-4-fluorobenzamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methyl-2-oxopiperidine-4-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrole-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]-1-methylpyrrolidine-3-carboxamide;N-[3-amino-6-(8-chloroquinolin-6-yl)-5-phenylpyrazin-2-yl]pyridine-3-carboxamide is sourced from PubChem (CID 158123130), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).