N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide

C122H126ClF4N31O10 — CID 158144238

IUPACN-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide
SMILESCC(=O)N1CCN(c2ccc(NC(=O)Cc3ccc(-c4ccnc(C)c4)nc3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(C#N)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(C(F)(F)F)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(Cl)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(F)c3)nc2)CC1
InChIInChI=1S/C25H25F3N6O2.C25H25N7O2.C24H25ClN6O2.C24H25FN6O2.C24H26N6O2/c1-16-11-19(5-6-29-16)24-21(25(26,27)28)12-18(14-31-24)13-23(36)32-22-4-3-20(15-30-22)34-9-7-33(8-10-34)17(2)35;1-17-11-20(5-6-27-17)25-21(14-26)12-19(15-29-25)13-24(34)30-23-4-3-22(16-28-23)32-9-7-31(8-10-32)18(2)33;2*1-16-11-19(5-6-26-16)24-21(25)12-18(14-28-24)13-23(33)29-22-4-3-20(15-27-22)31-9-7-30(8-10-31)17(2)32;1-17-13-20(7-8-25-17)22-5-3-19(15-26-22)14-24(32)28-23-6-4-21(16-27-23)30-11-9-29(10-12-30)18(2)31/h3-6,11-12,14-15H,7-10,13H2,1-2H3,(H,30,32,36);3-6,11-12,15-16H,7-10,13H2,1-2H3,(H,28,30,34);2*3-6,11-12,14-15H,7-10,13H2,1-2H3,(H,27,29,33);3-8,13,15-16H,9-12,14H2,1-2H3,(H,27,28,32)
InChIKeyFUHWCIWDJZZIAG-UHFFFAOYSA-N
MW2298.00 g/mol
LogP15.17
Rot. Bonds25

About N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide

N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide (PubChem CID 158144238) has the molecular formula C122H126ClF4N31O10 and a molecular weight of 2298.00 g/mol. Its IUPAC name is N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide.

Molecular Properties

Compound NameN-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide
PubChem CID158144238
Molecular FormulaC122H126ClF4N31O10
Molecular Weight2298.00 g/mol
Exact Mass2295.99
IUPAC NameN-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide
SMILESCC(=O)N1CCN(c2ccc(NC(=O)Cc3ccc(-c4ccnc(C)c4)nc3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(C#N)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(C(F)(F)F)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(Cl)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(F)c3)nc2)CC1
InChIInChI=1S/C25H25F3N6O2.C25H25N7O2.C24H25ClN6O2.C24H25FN6O2.C24H26N6O2/c1-16-11-19(5-6-29-16)24-21(25(26,27)28)12-18(14-31-24)13-23(36)32-22-4-3-20(15-30-22)34-9-7-33(8-10-34)17(2)35;1-17-11-20(5-6-27-17)25-21(14-26)12-19(15-29-25)13-24(34)30-23-4-3-22(16-28-23)32-9-7-31(8-10-32)18(2)33;2*1-16-11-19(5-6-26-16)24-21(25)12-18(14-28-24)13-23(33)29-22-4-3-20(15-27-22)31-9-7-30(8-10-31)17(2)32;1-17-13-20(7-8-25-17)22-5-3-19(15-26-22)14-24(32)28-23-6-4-21(16-27-23)30-11-9-29(10-12-30)18(2)31/h3-6,11-12,14-15H,7-10,13H2,1-2H3,(H,30,32,36);3-6,11-12,15-16H,7-10,13H2,1-2H3,(H,28,30,34);2*3-6,11-12,14-15H,7-10,13H2,1-2H3,(H,27,29,33);3-8,13,15-16H,9-12,14H2,1-2H3,(H,27,28,32)
InChIKeyFUHWCIWDJZZIAG-UHFFFAOYSA-N
XLogP15.17
TPSA480.39 Ų
H-Bond Donors5
H-Bond Acceptors31
Rotatable Bonds25
Heavy Atoms168
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002298.00
LogP ≤ 515.17
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1031

Analyze N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide with MolForge

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Launch Full Analysis

Related Compounds

Gnf6231
CID 46927297
US10251893, Cpd 189
CID 46927295
US10251893, Cpd 190
CID 46927296
US10251893, Cpd 194
CID 46927363
US10251893, Cpd 209
CID 46927366
2-(4-Chlorophenyl)-1-[4-[[5-[4-methyl-6-[[4-(trifluoromethyl)-2-pyridinyl]amino]-2-pyridinyl]-2-pyridinyl]amino]piperidin-1-yl]ethanone
CID 119098998
2-(2-Chlorophenyl)-1-[4-[[5-[4-methyl-6-[[4-(trifluoromethyl)-2-pyridinyl]amino]-2-pyridinyl]-2-pyridinyl]amino]piperidin-1-yl]ethanone
CID 119099020
2-(3-Chlorophenyl)-1-[4-[[5-[4-methyl-6-[[4-(trifluoromethyl)-2-pyridinyl]amino]-2-pyridinyl]-2-pyridinyl]amino]piperidin-1-yl]ethanone
CID 119099032
(M)-N-[2-[6-Chloro-4-[(2S,5R)-2,5-dimethyl-4-prop-2-enoyl-piperazin-1-yl]-1-(2-isopropyl-4-methyl-3-pyridyl)-2-oxo-pyrido[2,3-d]pyrimidin-7-yl]-3-fluoro-phenyl]-2,2,2-trifluoro-acetamide
CID 164515231
US10251893, Cpd 188
CID 58447743
US10251893, Cpd 184
CID 58447928
US10251893, Cpd 240
CID 58447674

Frequently Asked Questions

What is the IUPAC name of N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide?
The IUPAC name of N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide (CID 158144238) is N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide.
What is the SMILES notation for N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide?
The canonical SMILES for N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide is CC(=O)N1CCN(c2ccc(NC(=O)Cc3ccc(-c4ccnc(C)c4)nc3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(C#N)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(C(F)(F)F)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(Cl)c3)nc2)CC1.CC(=O)N1CCN(c2ccc(NC(=O)Cc3cnc(-c4ccnc(C)c4)c(F)c3)nc2)CC1.
What is the InChIKey of N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide?
The InChIKey is FUHWCIWDJZZIAG-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H25F3N6O2.C25H25N7O2.C24H25ClN6O2.C24H25FN6O2.C24H26N6O2/c1-16-11-19(5-6-29-16)24-21(25(26,27)28)12-18(14-31-24)13-23(36)32-22-4-3-20(15-30-22)34-9-7-33(8-10-34)17(2)35;1-17-11-20(5-6-27-17)25-21(14-26)12-19(15-29-25)13-24(34)30-23-4-3-22(16-28-23)32-9-7-31(8-10-32)18(2)33;2*1-16-11-19(5-6-26-16)24-21(25)12-18(14-28-24)13-23(33)29-22-4-3-20(15-27-22)31-9-7-30(8-10-31)17(2)32;1-17-13-20(7-8-25-17)22-5-3-19(15-26-22)14-24(32)28-23-6-4-21(16-27-23)30-11-9-29(10-12-30)18(2)31/h3-6,11-12,14-15H,7-10,13H2,1-2H3,(H,30,32,36);3-6,11-12,15-16H,7-10,13H2,1-2H3,(H,28,30,34);2*3-6,11-12,14-15H,7-10,13H2,1-2H3,(H,27,29,33);3-8,13,15-16H,9-12,14H2,1-2H3,(H,27,28,32).
What are the key properties of N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide?
N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide has a molecular weight of 2298.00 g/mol, XLogP of 15.17, 25 rotatable bonds, 5 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-chloro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-cyano-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[5-fluoro-6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-3-pyridinyl]acetamide;N-[5-(4-acetylpiperazin-1-yl)-2-pyridinyl]-2-[6-(2-methyl-4-pyridinyl)-5-(trifluoromethyl)-3-pyridinyl]acetamide is sourced from PubChem (CID 158144238), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).