3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one

C134H200N20O9 — CID 158146381

About 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one

3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 158146381) has the molecular formula C134H200N20O9 and a molecular weight of 2235.20 g/mol. Its IUPAC name is 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

• Compound Name: 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one
• PubChem CID: 158146381
• Molecular Formula: C134H200N20O9
• Molecular Weight: 2235.20 g/mol
• Exact Mass: 2233.58
• IUPAC Name: 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one
• SMILES: CC(=O)N1CCC(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CC3)C2=O)CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(c3cncnc3)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCNCC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)O)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CCC1(O)CCOCC1)C(=O)N2CC1CCC1
• InChI: InChI=1S/C29H40N6O.C28H42N4O2.C28H43N3O3.C25H38N4O.C24H37N3O2/c1-32(2)29(24-6-4-3-5-7-24)14-12-28(13-15-29)21-34(27(36)35(28)20-23-8-9-23)25-10-16-33(17-11-25)26-18-30-22-31-19-26;1-22(33)30-17-11-24(12-18-30)19-31-21-27(32(26(31)34)20-23-9-10-23)13-15-28(16-14-27,29(2)3)25-7-5-4-6-8-25;1-29(2)28(24-9-4-3-5-10-24)13-11-26(12-14-28)22-30(18-15-27(33)16-19-34-20-17-27)25(32)31(26)21-23-7-6-8-23;1-27(2)25(21-6-4-3-5-7-21)14-12-24(13-15-25)19-28(22-10-16-26-17-11-22)23(30)29(24)18-20-8-9-20;1-22(2,29)17-26-18-23(27(21(26)28)16-19-10-11-19)12-14-24(15-13-23,25(3)4)20-8-6-5-7-9-20/h3-7,18-19,22-23,25H,8-17,20-21H2,1-2H3;4-8,23-24H,9-21H2,1-3H3;3-5,9-10,23,33H,6-8,11-22H2,1-2H3;3-7,20,22,26H,8-19H2,1-2H3;5-9,19,29H,10-18H2,1-4H3
• InChIKey: FUOJXFJVWLZHFG-UHFFFAOYSA-N
• XLogP: 20.08
• TPSA: 245.00 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 18
• Rotatable Bonds: 30
• Heavy Atoms: 163
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2235.20
LogP ≤ 5	20.08
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	18

Frequently Asked Questions

What is the IUPAC name of 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one?

The IUPAC name of 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one (CID 158146381) is 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one.

What is the SMILES notation for 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one?

The canonical SMILES for 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one is CC(=O)N1CCC(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CC3)C2=O)CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCN(c3cncnc3)CC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(C1CCNCC1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(C)(C)O)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CCC1(O)CCOCC1)C(=O)N2CC1CCC1.

What is the InChIKey of 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one?

The InChIKey is FUOJXFJVWLZHFG-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H40N6O.C28H42N4O2.C28H43N3O3.C25H38N4O.C24H37N3O2/c1-32(2)29(24-6-4-3-5-7-24)14-12-28(13-15-29)21-34(27(36)35(28)20-23-8-9-23)25-10-16-33(17-11-25)26-18-30-22-31-19-26;1-22(33)30-17-11-24(12-18-30)19-31-21-27(32(26(31)34)20-23-9-10-23)13-15-28(16-14-27,29(2)3)25-7-5-4-6-8-25;1-29(2)28(24-9-4-3-5-10-24)13-11-26(12-14-28)22-30(18-15-27(33)16-19-34-20-17-27)25(32)31(26)21-23-7-6-8-23;1-27(2)25(21-6-4-3-5-7-21)14-12-24(13-15-25)19-28(22-10-16-26-17-11-22)23(30)29(24)18-20-8-9-20;1-22(2,29)17-26-18-23(27(21(26)28)16-19-10-11-19)12-14-24(15-13-23,25(3)4)20-8-6-5-7-9-20/h3-7,18-19,22-23,25H,8-17,20-21H2,1-2H3;4-8,23-24H,9-21H2,1-3H3;3-5,9-10,23,33H,6-8,11-22H2,1-2H3;3-7,20,22,26H,8-19H2,1-2H3;5-9,19,29H,10-18H2,1-4H3.

What are the key properties of 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one?

3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 2235.20 g/mol, XLogP of 20.08, 30 rotatable bonds, 3 hydrogen bond donors, and 18 hydrogen bond acceptors.

Where does this data come from?

All data for 3-[(1-acetylpiperidin-4-yl)methyl]-1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[2-(4-hydroxyoxan-4-yl)ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-3-(2-hydroxy-2-methylpropyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-piperidin-4-yl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclopropylmethyl)-8-(dimethylamino)-8-phenyl-3-(1-pyrimidin-5-ylpiperidin-4-yl)-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 158146381), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).