5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide

C127H128F2N30O10S7 — CID 158159661

About 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide

5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide (PubChem CID 158159661) has the molecular formula C127H128F2N30O10S7 and a molecular weight of 2497.09 g/mol. Its IUPAC name is 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide.

Molecular Properties

• Compound Name: 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide
• PubChem CID: 158159661
• Molecular Formula: C127H128F2N30O10S7
• Molecular Weight: 2497.09 g/mol
• Exact Mass: 2494.84
• IUPAC Name: 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide
• SMILES: Cc1cc(C)c(-c2ccc(CNC(=O)c3sc4nnc(C)c(C)c4c3N)cc2)cn1.Cc1ccc(S(=O)(=O)N2CCC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)cc1.Cc1cncc(-c2ccc(CNC(=O)c3sc4nnc(C)c(C)c4c3N)cc2)c1.Cc1nnc2sc(C(=O)NC3CCN(C(=O)C4CC4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CCN(C(=O)c4c(F)cccc4F)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NCc3ccc(-c4cnc5ccccc5c4)cc3)c(N)c2c1C
• InChI: InChI=1S/C25H21N5OS.C23H23N5OS.C22H21N5OS.C20H19F2N5O2S.C20H23N5O3S2.C17H21N5O2S/c1-14-15(2)29-30-25-21(14)22(26)23(32-25)24(31)28-12-16-7-9-17(10-8-16)19-11-18-5-3-4-6-20(18)27-13-19;1-12-9-13(2)25-11-18(12)17-7-5-16(6-8-17)10-26-22(29)21-20(24)19-14(3)15(4)27-28-23(19)30-21;1-12-8-17(11-24-9-12)16-6-4-15(5-7-16)10-25-21(28)20-19(23)18-13(2)14(3)26-27-22(18)29-20;1-9-10(2)25-26-19-14(9)16(23)17(30-19)18(28)24-11-6-7-27(8-11)20(29)15-12(21)4-3-5-13(15)22;1-11-4-6-15(7-5-11)30(27,28)25-9-8-14(10-25)22-19(26)18-17(21)16-12(2)13(3)23-24-20(16)29-18;1-8-9(2)20-21-16-12(8)13(18)14(25-16)15(23)19-11-5-6-22(7-11)17(24)10-3-4-10/h3-11,13H,12,26H2,1-2H3,(H,28,31);5-9,11H,10,24H2,1-4H3,(H,26,29);4-9,11H,10,23H2,1-3H3,(H,25,28);3-5,11H,6-8,23H2,1-2H3,(H,24,28);4-7,14H,8-10,21H2,1-3H3,(H,22,26);10-11H,3-7,18H2,1-2H3,(H,19,23)
• InChIKey: FWCQLFBHQGASDI-UHFFFAOYSA-N
• XLogP: 20.56
• TPSA: 602.07 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 37
• Rotatable Bonds: 22
• Heavy Atoms: 176
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2497.09
LogP ≤ 5	20.56
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide?

The IUPAC name of 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide (CID 158159661) is 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide.

What is the SMILES notation for 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide?

The canonical SMILES for 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide is Cc1cc(C)c(-c2ccc(CNC(=O)c3sc4nnc(C)c(C)c4c3N)cc2)cn1.Cc1ccc(S(=O)(=O)N2CCC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)cc1.Cc1cncc(-c2ccc(CNC(=O)c3sc4nnc(C)c(C)c4c3N)cc2)c1.Cc1nnc2sc(C(=O)NC3CCN(C(=O)C4CC4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CCN(C(=O)c4c(F)cccc4F)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NCc3ccc(-c4cnc5ccccc5c4)cc3)c(N)c2c1C.

What is the InChIKey of 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide?

The InChIKey is FWCQLFBHQGASDI-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H21N5OS.C23H23N5OS.C22H21N5OS.C20H19F2N5O2S.C20H23N5O3S2.C17H21N5O2S/c1-14-15(2)29-30-25-21(14)22(26)23(32-25)24(31)28-12-16-7-9-17(10-8-16)19-11-18-5-3-4-6-20(18)27-13-19;1-12-9-13(2)25-11-18(12)17-7-5-16(6-8-17)10-26-22(29)21-20(24)19-14(3)15(4)27-28-23(19)30-21;1-12-8-17(11-24-9-12)16-6-4-15(5-7-16)10-25-21(28)20-19(23)18-13(2)14(3)26-27-22(18)29-20;1-9-10(2)25-26-19-14(9)16(23)17(30-19)18(28)24-11-6-7-27(8-11)20(29)15-12(21)4-3-5-13(15)22;1-11-4-6-15(7-5-11)30(27,28)25-9-8-14(10-25)22-19(26)18-17(21)16-12(2)13(3)23-24-20(16)29-18;1-8-9(2)20-21-16-12(8)13(18)14(25-16)15(23)19-11-5-6-22(7-11)17(24)10-3-4-10/h3-11,13H,12,26H2,1-2H3,(H,28,31);5-9,11H,10,24H2,1-4H3,(H,26,29);4-9,11H,10,23H2,1-3H3,(H,25,28);3-5,11H,6-8,23H2,1-2H3,(H,24,28);4-7,14H,8-10,21H2,1-3H3,(H,22,26);10-11H,3-7,18H2,1-2H3,(H,19,23).

What are the key properties of 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide?

5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide has a molecular weight of 2497.09 g/mol, XLogP of 20.56, 22 rotatable bonds, 12 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 5-amino-N-[1-(cyclopropanecarbonyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(2,6-difluorobenzoyl)pyrrolidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-(4-methylphenyl)sulfonylpyrrolidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(5-methyl-3-pyridinyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[[4-(4,6-dimethyl-3-pyridinyl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[(4-quinolin-3-ylphenyl)methyl]thieno[2,3-c]pyridazine-6-carboxamide is sourced from PubChem (CID 158159661), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).