[4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone

C128H131BrClN33O5S3 — CID 158167019

About [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone

[4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone (PubChem CID 158167019) has the molecular formula C128H131BrClN33O5S3 and a molecular weight of 2423.24 g/mol. Its IUPAC name is [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone.

Molecular Properties

• Compound Name: [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone
• PubChem CID: 158167019
• Molecular Formula: C128H131BrClN33O5S3
• Molecular Weight: 2423.24 g/mol
• Exact Mass: 2419.90
• IUPAC Name: [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone
• SMILES: CCN(CC)C(=O)N1CCC(c2nc(-c3cc4cccc(Cl)c4[nH]3)c3c(N)ncnn23)CC1.CCc1ccc(Br)c2[nH]c(-c3nc(C4CCN(C(=O)c5ccsc5)CC4)n4ccnc(N)c34)cc12.CCc1cccc2[nH]c(-c3nc(C4CCN(C(=O)c5ccsc5)CC4)n4ccnc(N)c34)cc12.Cc1ccc(NC(=O)C2CCC(c3nc(-c4[nH]c5ccccc5c4C)c4c(N)nccn34)CC2)cn1.Cc1cccc2cc(-c3nc(C4CCN(C(=O)c5ccsc5)CC4)n4ccnc(N)c34)[nH]c12
• InChI: InChI=1S/C28H29N7O.C26H25BrN6OS.C26H26N6OS.C25H24N6OS.C23H27ClN8O/c1-16-7-12-20(15-31-16)32-28(36)19-10-8-18(9-11-19)27-34-24(25-26(29)30-13-14-35(25)27)23-17(2)21-5-3-4-6-22(21)33-23;1-2-15-3-4-19(27)21-18(15)13-20(30-21)22-23-24(28)29-8-11-33(23)25(31-22)16-5-9-32(10-6-16)26(34)17-7-12-35-14-17;1-2-16-4-3-5-20-19(16)14-21(29-20)22-23-24(27)28-9-12-32(23)25(30-22)17-6-10-31(11-7-17)26(33)18-8-13-34-15-18;1-15-3-2-4-17-13-19(28-20(15)17)21-22-23(26)27-8-11-31(22)24(29-21)16-5-9-30(10-6-16)25(32)18-7-12-33-14-18;1-3-30(4-2)23(33)31-10-8-14(9-11-31)22-29-19(20-21(25)26-13-27-32(20)22)17-12-15-6-5-7-16(24)18(15)28-17/h3-7,12-15,18-19,33H,8-11H2,1-2H3,(H2,29,30)(H,32,36);3-4,7-8,11-14,16,30H,2,5-6,9-10H2,1H3,(H2,28,29);3-5,8-9,12-15,17,29H,2,6-7,10-11H2,1H3,(H2,27,28);2-4,7-8,11-14,16,28H,5-6,9-10H2,1H3,(H2,26,27);5-7,12-14,28H,3-4,8-11H2,1-2H3,(H2,25,26,27)
• InChIKey: FWYUYMFHJVREBH-UHFFFAOYSA-N
• XLogP: 25.35
• TPSA: 499.36 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 30
• Rotatable Bonds: 19
• Heavy Atoms: 171
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2423.24
LogP ≤ 5	25.35
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'indol_3yl_alk(461)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone?

The IUPAC name of [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone (CID 158167019) is [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone.

What is the SMILES notation for [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone?

The canonical SMILES for [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone is CCN(CC)C(=O)N1CCC(c2nc(-c3cc4cccc(Cl)c4[nH]3)c3c(N)ncnn23)CC1.CCc1ccc(Br)c2[nH]c(-c3nc(C4CCN(C(=O)c5ccsc5)CC4)n4ccnc(N)c34)cc12.CCc1cccc2[nH]c(-c3nc(C4CCN(C(=O)c5ccsc5)CC4)n4ccnc(N)c34)cc12.Cc1ccc(NC(=O)C2CCC(c3nc(-c4[nH]c5ccccc5c4C)c4c(N)nccn34)CC2)cn1.Cc1cccc2cc(-c3nc(C4CCN(C(=O)c5ccsc5)CC4)n4ccnc(N)c34)[nH]c12.

What is the InChIKey of [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone?

The InChIKey is FWYUYMFHJVREBH-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H29N7O.C26H25BrN6OS.C26H26N6OS.C25H24N6OS.C23H27ClN8O/c1-16-7-12-20(15-31-16)32-28(36)19-10-8-18(9-11-19)27-34-24(25-26(29)30-13-14-35(25)27)23-17(2)21-5-3-4-6-22(21)33-23;1-2-15-3-4-19(27)21-18(15)13-20(30-21)22-23-24(28)29-8-11-33(23)25(31-22)16-5-9-32(10-6-16)26(34)17-7-12-35-14-17;1-2-16-4-3-5-20-19(16)14-21(29-20)22-23-24(27)28-9-12-32(23)25(30-22)17-6-10-31(11-7-17)26(33)18-8-13-34-15-18;1-15-3-2-4-17-13-19(28-20(15)17)21-22-23(26)27-8-11-31(22)24(29-21)16-5-9-30(10-6-16)25(32)18-7-12-33-14-18;1-3-30(4-2)23(33)31-10-8-14(9-11-31)22-29-19(20-21(25)26-13-27-32(20)22)17-12-15-6-5-7-16(24)18(15)28-17/h3-7,12-15,18-19,33H,8-11H2,1-2H3,(H2,29,30)(H,32,36);3-4,7-8,11-14,16,30H,2,5-6,9-10H2,1H3,(H2,28,29);3-5,8-9,12-15,17,29H,2,6-7,10-11H2,1H3,(H2,27,28);2-4,7-8,11-14,16,28H,5-6,9-10H2,1H3,(H2,26,27);5-7,12-14,28H,3-4,8-11H2,1-2H3,(H2,25,26,27).

What are the key properties of [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone?

[4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone has a molecular weight of 2423.24 g/mol, XLogP of 25.35, 19 rotatable bonds, 11 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for [4-[8-amino-1-(7-bromo-4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[4-amino-5-(7-chloro-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-N,N-diethylpiperidine-1-carboxamide;[4-[8-amino-1-(4-ethyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone;4-[8-amino-1-(3-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(6-methyl-3-pyridinyl)cyclohexane-1-carboxamide;[4-[8-amino-1-(7-methyl-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]-thiophen-3-ylmethanone is sourced from PubChem (CID 158167019), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).