N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide

C83H98N24O8 — CID 158177391

IUPACN-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
SMILESCC(C)[C@@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.CC(C)[C@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.O=C(Nc1cc(N2CCCCC2CCO)nc2c(C3CC3)cnn12)c1cccnc1.O=C(Nc1cc(N2CCCCC2CO)nc2c(C3CC3)cnn12)c1cccnc1
InChIInChI=1S/C22H26N6O2.C21H24N6O2.2C20H24N6O2/c29-11-8-17-5-1-2-10-27(17)19-12-20(26-22(30)16-4-3-9-23-13-16)28-21(25-19)18(14-24-28)15-6-7-15;28-13-16-5-1-2-9-26(16)18-10-19(25-21(29)15-4-3-8-22-11-15)27-20(24-18)17(12-23-27)14-6-7-14;2*1-12(2)16(11-27)23-17-8-18(25-20(28)14-4-3-7-21-9-14)26-19(24-17)15(10-22-26)13-5-6-13/h3-4,9,12-15,17,29H,1-2,5-8,10-11H2,(H,26,30);3-4,8,10-12,14,16,28H,1-2,5-7,9,13H2,(H,25,29);2*3-4,7-10,12-13,16,27H,5-6,11H2,1-2H3,(H,23,24)(H,25,28)/t;;2*16-/m..10/s1
InChIKeyFYDXEKJCOKGMPW-QVHYZKQASA-N
MW1559.86 g/mol
LogP10.97
Rot. Bonds25

About N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide

N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide (PubChem CID 158177391) has the molecular formula C83H98N24O8 and a molecular weight of 1559.86 g/mol. Its IUPAC name is N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
PubChem CID158177391
Molecular FormulaC83H98N24O8
Molecular Weight1559.86 g/mol
Exact Mass1558.80
IUPAC NameN-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
SMILESCC(C)[C@@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.CC(C)[C@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.O=C(Nc1cc(N2CCCCC2CCO)nc2c(C3CC3)cnn12)c1cccnc1.O=C(Nc1cc(N2CCCCC2CO)nc2c(C3CC3)cnn12)c1cccnc1
InChIInChI=1S/C22H26N6O2.C21H24N6O2.2C20H24N6O2/c29-11-8-17-5-1-2-10-27(17)19-12-20(26-22(30)16-4-3-9-23-13-16)28-21(25-19)18(14-24-28)15-6-7-15;28-13-16-5-1-2-9-26(16)18-10-19(25-21(29)15-4-3-8-22-11-15)27-20(24-18)17(12-23-27)14-6-7-14;2*1-12(2)16(11-27)23-17-8-18(25-20(28)14-4-3-7-21-9-14)26-19(24-17)15(10-22-26)13-5-6-13/h3-4,9,12-15,17,29H,1-2,5-8,10-11H2,(H,26,30);3-4,8,10-12,14,16,28H,1-2,5-7,9,13H2,(H,25,29);2*3-4,7-10,12-13,16,27H,5-6,11H2,1-2H3,(H,23,24)(H,25,28)/t;;2*16-/m..10/s1
InChIKeyFYDXEKJCOKGMPW-QVHYZKQASA-N
XLogP10.97
TPSA400.18 Ų
H-Bond Donors10
H-Bond Acceptors28
Rotatable Bonds25
Heavy Atoms115
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001559.86
LogP ≤ 510.97
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1028

Analyze N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157207969
6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158808370
6-cyclopropyl-2-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 158885401
6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[5-(trifluoromethyl)-2-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 159794332
6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[6-(trifluoromethyl)-3-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2,6-dimethyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 160281190
6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 161436457
6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 161687489
6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-2-methyl-N-[4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 162189617
N-(1-cyclopropylethyl)-5-(3,3-difluoropiperidin-1-yl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropylethyl)-5-ethyl-7-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropylethyl)-7-ethyl-5-pyridin-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropylethyl)-7-methyl-5-morpholin-4-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2-cyclopropylpropan-2-yl)-7-methyl-5-morpholin-4-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163502094
N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
CID 9977069
N-[3-cyclopropyl-5-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
CID 9999709
N-[3-cyclopropyl-5-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide
CID 10045203

Frequently Asked Questions

What is the IUPAC name of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?
The IUPAC name of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide (CID 158177391) is N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide.
What is the SMILES notation for N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?
The canonical SMILES for N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide is CC(C)[C@@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.CC(C)[C@H](CO)Nc1cc(NC(=O)c2cccnc2)n2ncc(C3CC3)c2n1.O=C(Nc1cc(N2CCCCC2CCO)nc2c(C3CC3)cnn12)c1cccnc1.O=C(Nc1cc(N2CCCCC2CO)nc2c(C3CC3)cnn12)c1cccnc1.
What is the InChIKey of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?
The InChIKey is FYDXEKJCOKGMPW-QVHYZKQASA-N. The full InChI is InChI=1S/C22H26N6O2.C21H24N6O2.2C20H24N6O2/c29-11-8-17-5-1-2-10-27(17)19-12-20(26-22(30)16-4-3-9-23-13-16)28-21(25-19)18(14-24-28)15-6-7-15;28-13-16-5-1-2-9-26(16)18-10-19(25-21(29)15-4-3-8-22-11-15)27-20(24-18)17(12-23-27)14-6-7-14;2*1-12(2)16(11-27)23-17-8-18(25-20(28)14-4-3-7-21-9-14)26-19(24-17)15(10-22-26)13-5-6-13/h3-4,9,12-15,17,29H,1-2,5-8,10-11H2,(H,26,30);3-4,8,10-12,14,16,28H,1-2,5-7,9,13H2,(H,25,29);2*3-4,7-10,12-13,16,27H,5-6,11H2,1-2H3,(H,23,24)(H,25,28)/t;;2*16-/m..10/s1.
What are the key properties of N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide?
N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide has a molecular weight of 1559.86 g/mol, XLogP of 10.97, 25 rotatable bonds, 10 hydrogen bond donors, and 28 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-cyclopropyl-5-[2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2R)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide;N-[3-cyclopropyl-5-[2-(hydroxymethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]pyridine-3-carboxamide is sourced from PubChem (CID 158177391), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).