2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide

C107H99Cl2F5N26O5S2 — CID 158179820

About 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide

2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide (PubChem CID 158179820) has the molecular formula C107H99Cl2F5N26O5S2 and a molecular weight of 2059.18 g/mol. Its IUPAC name is 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide.

Molecular Properties

• Compound Name: 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide
• PubChem CID: 158179820
• Molecular Formula: C107H99Cl2F5N26O5S2
• Molecular Weight: 2059.18 g/mol
• Exact Mass: 2056.70
• IUPAC Name: 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide
• SMILES: CC1=C(c2ccc(NC(=O)c3ccccc3F)cc2)CN(c2nnn(C)n2)CC1.CC1=C(c2ccc(NC(=O)c3sccc3C)cc2)CN(c2nccs2)CC1.CC1=C(c2cnc(NC(=O)c3cc(F)ccc3F)cn2)CN(c2ncccc2F)CC1.CC1=C(c2cnc(NC(=O)c3ccccc3Cl)cn2)CN(c2nccnc2Cl)CC1.CC1=C(c2cnc(NC(=O)c3cnccc3C)cn2)CN(c2ncccc2F)CC1
• InChI: InChI=1S/C22H18F3N5O.C22H21FN6O.C21H18Cl2N6O.C21H21FN6O.C21H21N3OS2/c1-13-6-8-30(21-18(25)3-2-7-26-21)12-16(13)19-10-28-20(11-27-19)29-22(31)15-9-14(23)4-5-17(15)24;1-14-5-8-24-10-16(14)22(30)28-20-12-26-19(11-27-20)17-13-29(9-6-15(17)2)21-18(23)4-3-7-25-21;1-13-6-9-29(20-19(23)24-7-8-25-20)12-15(13)17-10-27-18(11-26-17)28-21(30)14-4-2-3-5-16(14)22;1-14-11-12-28(21-24-26-27(2)25-21)13-18(14)15-7-9-16(10-8-15)23-20(29)17-5-3-4-6-19(17)22;1-14-7-10-24(21-22-9-12-27-21)13-18(14)16-3-5-17(6-4-16)23-20(25)19-15(2)8-11-26-19/h2-5,7,9-11H,6,8,12H2,1H3,(H,28,29,31);3-5,7-8,10-12H,6,9,13H2,1-2H3,(H,27,28,30);2-5,7-8,10-11H,6,9,12H2,1H3,(H,27,28,30);3-10H,11-13H2,1-2H3,(H,23,29);3-6,8-9,11-12H,7,10,13H2,1-2H3,(H,23,25)
• InChIKey: FYLIAVLHNTUCKW-UHFFFAOYSA-N
• XLogP: 21.12
• TPSA: 359.98 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 28
• Rotatable Bonds: 20
• Heavy Atoms: 147
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2059.18
LogP ≤ 5	21.12
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	28

Frequently Asked Questions

What is the IUPAC name of 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide?

The IUPAC name of 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide (CID 158179820) is 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide.

What is the SMILES notation for 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide?

The canonical SMILES for 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide is CC1=C(c2ccc(NC(=O)c3ccccc3F)cc2)CN(c2nnn(C)n2)CC1.CC1=C(c2ccc(NC(=O)c3sccc3C)cc2)CN(c2nccs2)CC1.CC1=C(c2cnc(NC(=O)c3cc(F)ccc3F)cn2)CN(c2ncccc2F)CC1.CC1=C(c2cnc(NC(=O)c3ccccc3Cl)cn2)CN(c2nccnc2Cl)CC1.CC1=C(c2cnc(NC(=O)c3cnccc3C)cn2)CN(c2ncccc2F)CC1.

What is the InChIKey of 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide?

The InChIKey is FYLIAVLHNTUCKW-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H18F3N5O.C22H21FN6O.C21H18Cl2N6O.C21H21FN6O.C21H21N3OS2/c1-13-6-8-30(21-18(25)3-2-7-26-21)12-16(13)19-10-28-20(11-27-19)29-22(31)15-9-14(23)4-5-17(15)24;1-14-5-8-24-10-16(14)22(30)28-20-12-26-19(11-27-20)17-13-29(9-6-15(17)2)21-18(23)4-3-7-25-21;1-13-6-9-29(20-19(23)24-7-8-25-20)12-15(13)17-10-27-18(11-26-17)28-21(30)14-4-2-3-5-16(14)22;1-14-11-12-28(21-24-26-27(2)25-21)13-18(14)15-7-9-16(10-8-15)23-20(29)17-5-3-4-6-19(17)22;1-14-7-10-24(21-22-9-12-27-21)13-18(14)16-3-5-17(6-4-16)23-20(25)19-15(2)8-11-26-19/h2-5,7,9-11H,6,8,12H2,1H3,(H,28,29,31);3-5,7-8,10-12H,6,9,13H2,1-2H3,(H,27,28,30);2-5,7-8,10-11H,6,9,12H2,1H3,(H,27,28,30);3-10H,11-13H2,1-2H3,(H,23,29);3-6,8-9,11-12H,7,10,13H2,1-2H3,(H,23,25).

What are the key properties of 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide?

2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide has a molecular weight of 2059.18 g/mol, XLogP of 21.12, 20 rotatable bonds, 5 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 2-chloro-N-[5-[1-(3-chloropyrazin-2-yl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2,5-difluoro-N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[4-[4-methyl-1-(2-methyltetrazol-5-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]benzamide;N-[5-[1-(3-fluoro-2-pyridinyl)-4-methyl-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide;3-methyl-N-[4-[4-methyl-1-(1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]phenyl]thiophene-2-carboxamide is sourced from PubChem (CID 158179820), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).