5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide

C105H137F11N20O12S4 — CID 158186347

IUPAC5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide
SMILESCC(C)(O)CNC(=O)c1nc(C(=O)N2CCC(F)CC2)c(-c2cnc(NC3CCCC(F)(F)C3)c(C(F)(F)F)c2)s1.Cc1cc(NC2CC(C)(F)C2)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1.Cc1cc(NC2CC3(C2)CC(C)(F)C3)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1.Cc1cc(NC2CCCCC2)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1
InChIInChI=1S/C28H37F2N5O3S.C26H31F6N5O3S.C26H36FN5O3S.C25H33F2N5O3S/c1-16-9-20(33-18-10-28(11-18)13-27(4,30)14-28)31-12-19(16)22-21(25(37)35-7-5-17(29)6-8-35)34-24(39-22)23(36)32-15-26(2,3)38;1-24(2,40)13-34-21(38)22-36-18(23(39)37-8-5-15(27)6-9-37)19(41-22)14-10-17(26(30,31)32)20(33-12-14)35-16-4-3-7-25(28,29)11-16;1-16-13-20(30-18-7-5-4-6-8-18)28-14-19(16)22-21(25(34)32-11-9-17(27)10-12-32)31-24(36-22)23(33)29-15-26(2,3)35;1-14-9-18(30-16-10-25(4,27)11-16)28-12-17(14)20-19(23(34)32-7-5-15(26)6-8-32)31-22(36-20)21(33)29-13-24(2,3)35/h9,12,17-18,38H,5-8,10-11,13-15H2,1-4H3,(H,31,33)(H,32,36);10,12,15-16,40H,3-9,11,13H2,1-2H3,(H,33,35)(H,34,38);13-14,17-18,35H,4-12,15H2,1-3H3,(H,28,30)(H,29,33);9,12,15-16,35H,5-8,10-11,13H2,1-4H3,(H,28,30)(H,29,33)
InChIKeyFZELZZOJOSRSLJ-UHFFFAOYSA-N
MW2208.62 g/mol
LogP18.18
Rot. Bonds28

About 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide

5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide (PubChem CID 158186347) has the molecular formula C105H137F11N20O12S4 and a molecular weight of 2208.62 g/mol. Its IUPAC name is 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide.

Molecular Properties

Compound Name5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide
PubChem CID158186347
Molecular FormulaC105H137F11N20O12S4
Molecular Weight2208.62 g/mol
Exact Mass2206.94
IUPAC Name5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide
SMILESCC(C)(O)CNC(=O)c1nc(C(=O)N2CCC(F)CC2)c(-c2cnc(NC3CCCC(F)(F)C3)c(C(F)(F)F)c2)s1.Cc1cc(NC2CC(C)(F)C2)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1.Cc1cc(NC2CC3(C2)CC(C)(F)C3)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1.Cc1cc(NC2CCCCC2)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1
InChIInChI=1S/C28H37F2N5O3S.C26H31F6N5O3S.C26H36FN5O3S.C25H33F2N5O3S/c1-16-9-20(33-18-10-28(11-18)13-27(4,30)14-28)31-12-19(16)22-21(25(37)35-7-5-17(29)6-8-35)34-24(39-22)23(36)32-15-26(2,3)38;1-24(2,40)13-34-21(38)22-36-18(23(39)37-8-5-15(27)6-9-37)19(41-22)14-10-17(26(30,31)32)20(33-12-14)35-16-4-3-7-25(28,29)11-16;1-16-13-20(30-18-7-5-4-6-8-18)28-14-19(16)22-21(25(34)32-11-9-17(27)10-12-32)31-24(36-22)23(33)29-15-26(2,3)35;1-14-9-18(30-16-10-25(4,27)11-16)28-12-17(14)20-19(23(34)32-7-5-15(26)6-8-32)31-22(36-20)21(33)29-13-24(2,3)35/h9,12,17-18,38H,5-8,10-11,13-15H2,1-4H3,(H,31,33)(H,32,36);10,12,15-16,40H,3-9,11,13H2,1-2H3,(H,33,35)(H,34,38);13-14,17-18,35H,4-12,15H2,1-3H3,(H,28,30)(H,29,33);9,12,15-16,35H,5-8,10-11,13H2,1-4H3,(H,28,30)(H,29,33)
InChIKeyFZELZZOJOSRSLJ-UHFFFAOYSA-N
XLogP18.18
TPSA429.80 Ų
H-Bond Donors12
H-Bond Acceptors28
Rotatable Bonds28
Heavy Atoms152
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002208.62
LogP ≤ 518.18
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1028

Analyze 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide with MolForge

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Related Compounds

US10975068, Example 99
CID 132057454
US10975068, Example 274
CID 132057787
US10975068, Example 116
CID 132056908
US10975068, Example 24
CID 132057195
US10975068, Example 122
CID 132057278
US10975068, Example 89
CID 132057294
US10975068, Example 22
CID 132057307
US10975068, Example 446
CID 132057327
US10975068, Example 46
CID 132057375
US10975068, Example 242
CID 132057603
US10975068, Example 93
CID 132057628
US10975068, Example 140
CID 132057663

Frequently Asked Questions

What is the IUPAC name of 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide?
The IUPAC name of 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide (CID 158186347) is 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide.
What is the SMILES notation for 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide?
The canonical SMILES for 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide is CC(C)(O)CNC(=O)c1nc(C(=O)N2CCC(F)CC2)c(-c2cnc(NC3CCCC(F)(F)C3)c(C(F)(F)F)c2)s1.Cc1cc(NC2CC(C)(F)C2)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1.Cc1cc(NC2CC3(C2)CC(C)(F)C3)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1.Cc1cc(NC2CCCCC2)ncc1-c1sc(C(=O)NCC(C)(C)O)nc1C(=O)N1CCC(F)CC1.
What is the InChIKey of 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide?
The InChIKey is FZELZZOJOSRSLJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H37F2N5O3S.C26H31F6N5O3S.C26H36FN5O3S.C25H33F2N5O3S/c1-16-9-20(33-18-10-28(11-18)13-27(4,30)14-28)31-12-19(16)22-21(25(37)35-7-5-17(29)6-8-35)34-24(39-22)23(36)32-15-26(2,3)38;1-24(2,40)13-34-21(38)22-36-18(23(39)37-8-5-15(27)6-9-37)19(41-22)14-10-17(26(30,31)32)20(33-12-14)35-16-4-3-7-25(28,29)11-16;1-16-13-20(30-18-7-5-4-6-8-18)28-14-19(16)22-21(25(34)32-11-9-17(27)10-12-32)31-24(36-22)23(33)29-15-26(2,3)35;1-14-9-18(30-16-10-25(4,27)11-16)28-12-17(14)20-19(23(34)32-7-5-15(26)6-8-32)31-22(36-20)21(33)29-13-24(2,3)35/h9,12,17-18,38H,5-8,10-11,13-15H2,1-4H3,(H,31,33)(H,32,36);10,12,15-16,40H,3-9,11,13H2,1-2H3,(H,33,35)(H,34,38);13-14,17-18,35H,4-12,15H2,1-3H3,(H,28,30)(H,29,33);9,12,15-16,35H,5-8,10-11,13H2,1-4H3,(H,28,30)(H,29,33).
What are the key properties of 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide?
5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide has a molecular weight of 2208.62 g/mol, XLogP of 18.18, 28 rotatable bonds, 12 hydrogen bond donors, and 28 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[6-(cyclohexylamino)-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3,3-difluorocyclohexyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(3-fluoro-3-methylcyclobutyl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[(2-fluoro-2-methylspiro[3.3]heptan-6-yl)amino]-4-methyl-3-pyridinyl]-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide is sourced from PubChem (CID 158186347), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).