6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide

C128H114F26N26O14S6 — CID 158191630

About 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide

6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide (PubChem CID 158191630) has the molecular formula C128H114F26N26O14S6 and a molecular weight of 2926.84 g/mol. Its IUPAC name is 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide.

Molecular Properties

• Compound Name: 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide
• PubChem CID: 158191630
• Molecular Formula: C128H114F26N26O14S6
• Molecular Weight: 2926.84 g/mol
• Exact Mass: 2924.69
• IUPAC Name: 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide
• SMILES: CC(C)n1c(-c2ncc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)c(C#N)c2ccc(OC(F)F)cc21.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2CC2CC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(OC(F)F)cc3n2CC2CC2)nc1)C(F)(F)F
• InChI: InChI=1S/C23H22F4N4O2S.C22H20F4N4O2S.C21H18F5N5O3S.2C21H18F4N4O2S.C20H18F5N5O3S/c1-14(23(25,26)27)30-34(32,33)17-8-10-20(29-13-17)22-19(12-28)18-9-7-15(24)11-21(18)31(22)16-5-3-2-4-6-16;1-13(22(24,25)26)29-33(31,32)16-7-9-19(28-12-16)21-18(11-27)17-8-6-14(23)10-20(17)30(21)15-4-2-3-5-15;1-11(21(24,25)26)30-35(32,33)14-8-28-19(29-9-14)18-16(7-27)15-5-4-13(34-20(22)23)6-17(15)31(18)10-12-2-3-12;1-12(21(23,24)25)28-32(30,31)15-5-7-18(27-10-15)20-17(9-26)16-6-4-14(22)8-19(16)29(20)11-13-2-3-13;1-12(21(23,24)25)28-32(30,31)15-6-8-18(27-11-15)20-17(10-26)16-7-5-13(22)9-19(16)29(20)14-3-2-4-14;1-10(2)30-16-6-12(33-19(21)22)4-5-14(16)15(7-26)17(30)18-27-8-13(9-28-18)34(31,32)29-11(3)20(23,24)25/h7-11,13-14,16,30H,2-6H2,1H3;6-10,12-13,15,29H,2-5H2,1H3;4-6,8-9,11-12,20,30H,2-3,10H2,1H3;4-8,10,12-13,28H,2-3,11H2,1H3;5-9,11-12,14,28H,2-4H2,1H3;4-6,8-11,19,29H,1-3H3/t14-;13-;11-;2*12-;11-/m000000/s1
• InChIKey: FZVFEHLCSSOQMC-SLNIJGQESA-N
• XLogP: 28.12
• TPSA: 570.92 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 34
• Rotatable Bonds: 36
• Heavy Atoms: 200
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2926.84
LogP ≤ 5	28.12
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide?

The IUPAC name of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide (CID 158191630) is 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide.

What is the SMILES notation for 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide?

The canonical SMILES for 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide is CC(C)n1c(-c2ncc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)c(C#N)c2ccc(OC(F)F)cc21.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2CC2CC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(OC(F)F)cc3n2CC2CC2)nc1)C(F)(F)F.

What is the InChIKey of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide?

The InChIKey is FZVFEHLCSSOQMC-SLNIJGQESA-N. The full InChI is InChI=1S/C23H22F4N4O2S.C22H20F4N4O2S.C21H18F5N5O3S.2C21H18F4N4O2S.C20H18F5N5O3S/c1-14(23(25,26)27)30-34(32,33)17-8-10-20(29-13-17)22-19(12-28)18-9-7-15(24)11-21(18)31(22)16-5-3-2-4-6-16;1-13(22(24,25)26)29-33(31,32)16-7-9-19(28-12-16)21-18(11-27)17-8-6-14(23)10-20(17)30(21)15-4-2-3-5-15;1-11(21(24,25)26)30-35(32,33)14-8-28-19(29-9-14)18-16(7-27)15-5-4-13(34-20(22)23)6-17(15)31(18)10-12-2-3-12;1-12(21(23,24)25)28-32(30,31)15-5-7-18(27-10-15)20-17(9-26)16-6-4-14(22)8-19(16)29(20)11-13-2-3-13;1-12(21(23,24)25)28-32(30,31)15-6-8-18(27-11-15)20-17(10-26)16-7-5-13(22)9-19(16)29(20)14-3-2-4-14;1-10(2)30-16-6-12(33-19(21)22)4-5-14(16)15(7-26)17(30)18-27-8-13(9-28-18)34(31,32)29-11(3)20(23,24)25/h7-11,13-14,16,30H,2-6H2,1H3;6-10,12-13,15,29H,2-5H2,1H3;4-6,8-9,11-12,20,30H,2-3,10H2,1H3;4-8,10,12-13,28H,2-3,11H2,1H3;5-9,11-12,14,28H,2-4H2,1H3;4-6,8-11,19,29H,1-3H3/t14-;13-;11-;2*12-;11-/m000000/s1.

What are the key properties of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide?

6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide has a molecular weight of 2926.84 g/mol, XLogP of 28.12, 36 rotatable bonds, 6 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-(cyclopropylmethyl)-6-(difluoromethoxy)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyrimidine-5-sulfonamide is sourced from PubChem (CID 158191630), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).