1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

C109H155N17O8 — CID 158219966

IUPAC1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)CC(C)C)CC2)N(CC2CCC2)C1=O.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccncn1)C(=O)N2CC1CCC1.Cc1cccc(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1
InChIInChI=1S/C29H39N5O2.C28H43N3O2.C27H36N6O2.C25H37N3O2/c1-22-9-7-14-25(30-22)31-26(35)20-33-21-28(34(27(33)36)19-23-10-8-11-23)15-17-29(18-16-28,32(2)3)24-12-5-4-6-13-24;1-5-25(32)20-30-21-27(31(26(30)33)19-23-10-9-11-23)14-16-28(17-15-27,29(4)18-22(2)3)24-12-7-6-8-13-24;1-31(2)27(22-9-4-3-5-10-22)14-12-26(13-15-27)19-32(25(35)33(26)17-21-7-6-8-21)18-24(34)30-23-11-16-28-20-29-23;1-4-22(29)18-27-19-24(28(23(27)30)17-20-9-8-10-20)13-15-25(16-14-24,26(2)3)21-11-6-5-7-12-21/h4-7,9,12-14,23H,8,10-11,15-21H2,1-3H3,(H,30,31,35);6-8,12-13,22-23H,5,9-11,14-21H2,1-4H3;3-5,9-11,16,20-21H,6-8,12-15,17-19H2,1-2H3,(H,28,29,30,34);5-7,11-12,20H,4,8-10,13-19H2,1-3H3
InChIKeyGDCXCUGRJUJUST-UHFFFAOYSA-N
MW1831.55 g/mol
LogP17.93
Rot. Bonds30

About 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 158219966) has the molecular formula C109H155N17O8 and a molecular weight of 1831.55 g/mol. Its IUPAC name is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
PubChem CID158219966
Molecular FormulaC109H155N17O8
Molecular Weight1831.55 g/mol
Exact Mass1830.22
IUPAC Name1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)CC(C)C)CC2)N(CC2CCC2)C1=O.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccncn1)C(=O)N2CC1CCC1.Cc1cccc(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1
InChIInChI=1S/C29H39N5O2.C28H43N3O2.C27H36N6O2.C25H37N3O2/c1-22-9-7-14-25(30-22)31-26(35)20-33-21-28(34(27(33)36)19-23-10-8-11-23)15-17-29(18-16-28,32(2)3)24-12-5-4-6-13-24;1-5-25(32)20-30-21-27(31(26(30)33)19-23-10-9-11-23)14-16-28(17-15-27,29(4)18-22(2)3)24-12-7-6-8-13-24;1-31(2)27(22-9-4-3-5-10-22)14-12-26(13-15-27)19-32(25(35)33(26)17-21-7-6-8-21)18-24(34)30-23-11-16-28-20-29-23;1-4-22(29)18-27-19-24(28(23(27)30)17-20-9-8-10-20)13-15-25(16-14-24,26(2)3)21-11-6-5-7-12-21/h4-7,9,12-14,23H,8,10-11,15-21H2,1-3H3,(H,30,31,35);6-8,12-13,22-23H,5,9-11,14-21H2,1-4H3;3-5,9-11,16,20-21H,6-8,12-15,17-19H2,1-2H3,(H,28,29,30,34);5-7,11-12,20H,4,8-10,13-19H2,1-3H3
InChIKeyGDCXCUGRJUJUST-UHFFFAOYSA-N
XLogP17.93
TPSA238.17 Ų
H-Bond Donors2
H-Bond Acceptors15
Rotatable Bonds30
Heavy Atoms134
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001831.55
LogP ≤ 517.93
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 1015

Analyze 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one with MolForge

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Frequently Asked Questions

What is the IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (CID 158219966) is 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(CC2CCC2)C1=O.CCC(=O)CN1CC2(CCC(c3ccccc3)(N(C)CC(C)C)CC2)N(CC2CCC2)C1=O.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccncn1)C(=O)N2CC1CCC1.Cc1cccc(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)n1.
What is the InChIKey of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is GDCXCUGRJUJUST-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H39N5O2.C28H43N3O2.C27H36N6O2.C25H37N3O2/c1-22-9-7-14-25(30-22)31-26(35)20-33-21-28(34(27(33)36)19-23-10-8-11-23)15-17-29(18-16-28,32(2)3)24-12-5-4-6-13-24;1-5-25(32)20-30-21-27(31(26(30)33)19-23-10-9-11-23)14-16-28(17-15-27,29(4)18-22(2)3)24-12-7-6-8-13-24;1-31(2)27(22-9-4-3-5-10-22)14-12-26(13-15-27)19-32(25(35)33(26)17-21-7-6-8-21)18-24(34)30-23-11-16-28-20-29-23;1-4-22(29)18-27-19-24(28(23(27)30)17-20-9-8-10-20)13-15-25(16-14-24,26(2)3)21-11-6-5-7-12-21/h4-7,9,12-14,23H,8,10-11,15-21H2,1-3H3,(H,30,31,35);6-8,12-13,22-23H,5,9-11,14-21H2,1-4H3;3-5,9-11,16,20-21H,6-8,12-15,17-19H2,1-2H3,(H,28,29,30,34);5-7,11-12,20H,4,8-10,13-19H2,1-3H3.
What are the key properties of 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 1831.55 g/mol, XLogP of 17.93, 30 rotatable bonds, 2 hydrogen bond donors, and 15 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(cyclobutylmethyl)-8-(dimethylamino)-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(6-methyl-2-pyridinyl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-pyrimidin-4-ylacetamide;1-(cyclobutylmethyl)-8-[methyl(2-methylpropyl)amino]-3-(2-oxobutyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 158219966), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).