2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one

C110H103Cl5N18O16S — CID 158221055

About 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one

2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one (PubChem CID 158221055) has the molecular formula C110H103Cl5N18O16S and a molecular weight of 2142.48 g/mol. Its IUPAC name is 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one.

Molecular Properties

• Compound Name: 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one
• PubChem CID: 158221055
• Molecular Formula: C110H103Cl5N18O16S
• Molecular Weight: 2142.48 g/mol
• Exact Mass: 2138.60
• IUPAC Name: 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one
• SMILES: CC(=O)Cc1cc(-c2cc(C(=O)N(C)C)c(-c3ccccc3Cl)o2)c(C)cn1.CC(=O)Cc1cc(-c2nc(-c3nccs3)c(-c3ccccc3Cl)o2)c(C)cn1.CC(=O)Cc1cc(-c2nc(C(=O)NCCCn3ccnc3)c(-c3ccccc3Cl)o2)c(C)cn1.CC(=O)Nc1cc(-c2nc(C(=O)NC[C@@H](C)O)c(-c3ccccc3Cl)o2)c(C)cn1.COCCNC(=O)c1nc(-c2cc(NC(C)=O)ncc2C)oc1-c1ccccc1Cl
• InChI: InChI=1S/C25H24ClN5O3.C22H21ClN2O3.2C21H21ClN4O4.C21H16ClN3O2S/c1-16-14-29-18(12-17(2)32)13-20(16)25-30-22(23(34-25)19-6-3-4-7-21(19)26)24(33)28-8-5-10-31-11-9-27-15-31;1-13-12-24-15(9-14(2)26)10-17(13)20-11-18(22(27)25(3)4)21(28-20)16-7-5-6-8-19(16)23;1-11-9-23-17(25-13(3)28)8-15(11)21-26-18(20(29)24-10-12(2)27)19(30-21)14-6-4-5-7-16(14)22;1-12-11-24-17(25-13(2)27)10-15(12)21-26-18(20(28)23-8-9-29-3)19(30-21)14-6-4-5-7-16(14)22;1-12-11-24-14(9-13(2)26)10-16(12)20-25-18(21-23-7-8-28-21)19(27-20)15-5-3-4-6-17(15)22/h3-4,6-7,9,11,13-15H,5,8,10,12H2,1-2H3,(H,28,33);5-8,10-12H,9H2,1-4H3;4-9,12,27H,10H2,1-3H3,(H,24,29)(H,23,25,28);4-7,10-11H,8-9H2,1-3H3,(H,23,28)(H,24,25,27);3-8,10-11H,9H2,1-2H3/t;;12-;;/m..1../s1
• InChIKey: GDFZWYNHQGWHBB-SGUVDTOLSA-N
• XLogP: 22.07
• TPSA: 458.90 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 29
• Rotatable Bonds: 32
• Heavy Atoms: 150
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2142.48
LogP ≤ 5	22.07
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

The IUPAC name of 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one (CID 158221055) is 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one.

What is the SMILES notation for 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

The canonical SMILES for 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one is CC(=O)Cc1cc(-c2cc(C(=O)N(C)C)c(-c3ccccc3Cl)o2)c(C)cn1.CC(=O)Cc1cc(-c2nc(-c3nccs3)c(-c3ccccc3Cl)o2)c(C)cn1.CC(=O)Cc1cc(-c2nc(C(=O)NCCCn3ccnc3)c(-c3ccccc3Cl)o2)c(C)cn1.CC(=O)Nc1cc(-c2nc(C(=O)NC[C@@H](C)O)c(-c3ccccc3Cl)o2)c(C)cn1.COCCNC(=O)c1nc(-c2cc(NC(C)=O)ncc2C)oc1-c1ccccc1Cl.

What is the InChIKey of 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

The InChIKey is GDFZWYNHQGWHBB-SGUVDTOLSA-N. The full InChI is InChI=1S/C25H24ClN5O3.C22H21ClN2O3.2C21H21ClN4O4.C21H16ClN3O2S/c1-16-14-29-18(12-17(2)32)13-20(16)25-30-22(23(34-25)19-6-3-4-7-21(19)26)24(33)28-8-5-10-31-11-9-27-15-31;1-13-12-24-15(9-14(2)26)10-17(13)20-11-18(22(27)25(3)4)21(28-20)16-7-5-6-8-19(16)23;1-11-9-23-17(25-13(3)28)8-15(11)21-26-18(20(29)24-10-12(2)27)19(30-21)14-6-4-5-7-16(14)22;1-12-11-24-17(25-13(2)27)10-15(12)21-26-18(20(28)23-8-9-29-3)19(30-21)14-6-4-5-7-16(14)22;1-12-11-24-14(9-13(2)26)10-16(12)20-25-18(21-23-7-8-28-21)19(27-20)15-5-3-4-6-17(15)22/h3-4,6-7,9,11,13-15H,5,8,10,12H2,1-2H3,(H,28,33);5-8,10-12H,9H2,1-4H3;4-9,12,27H,10H2,1-3H3,(H,24,29)(H,23,25,28);4-7,10-11H,8-9H2,1-3H3,(H,23,28)(H,24,25,27);3-8,10-11H,9H2,1-2H3/t;;12-;;/m..1../s1.

What are the key properties of 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one has a molecular weight of 2142.48 g/mol, XLogP of 22.07, 32 rotatable bonds, 6 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-[(2R)-2-hydroxypropyl]-1,3-oxazole-4-carboxamide;2-(2-acetamido-5-methyl-4-pyridinyl)-5-(2-chlorophenyl)-N-(2-methoxyethyl)-1,3-oxazole-4-carboxamide;2-(2-chlorophenyl)-N,N-dimethyl-5-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]furan-3-carboxamide;5-(2-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-2-[5-methyl-2-(2-oxopropyl)-4-pyridinyl]-1,3-oxazole-4-carboxamide;1-[4-[5-(2-chlorophenyl)-4-(1,3-thiazol-2-yl)-1,3-oxazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one is sourced from PubChem (CID 158221055), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).