3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine

C90H66F27N25O5 — CID 158237164

IUPAC3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine
SMILESCC(C)Oc1ccc(-c2cn3c(C(C)(F)F)nnc3cn2)cc1.CC(F)(F)c1nnc2cnc(-c3ccc(C(F)(F)F)cc3F)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC(F)(F)F)c(F)c3)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC4CC(F)(F)C4)cc3)cn12.CC(F)(F)c1nnc2cnc(-c3cnc(OCC(F)(F)F)c(F)c3)cn12.FC(F)(F)Oc1ccc(-c2cn3c(C4CC4)nnc3cn2)cc1
InChIInChI=1S/C17H14F4N4O.C16H16F2N4O.C15H11F3N4O.C14H9F6N5O.C14H8F6N4O.C14H8F6N4/c1-16(18,19)15-24-23-14-8-22-13(9-25(14)15)10-2-4-11(5-3-10)26-12-6-17(20,21)7-12;1-10(2)23-12-6-4-11(5-7-12)13-9-22-14(8-19-13)20-21-15(22)16(3,17)18;16-15(17,18)23-11-5-3-9(4-6-11)12-8-22-13(7-19-12)20-21-14(22)10-1-2-10;1-13(16,17)12-24-23-10-4-21-9(5-25(10)12)7-2-8(15)11(22-3-7)26-6-14(18,19)20;1-13(16,17)12-23-22-11-5-21-9(6-24(11)12)7-2-3-10(8(15)4-7)25-14(18,19)20;1-13(16,17)12-23-22-11-5-21-10(6-24(11)12)8-3-2-7(4-9(8)15)14(18,19)20/h2-5,8-9,12H,6-7H2,1H3;4-10H,1-3H3;3-8,10H,1-2H2;2-5H,6H2,1H3;2-6H,1H3;2-6H,1H3
InChIKeyGFCHWJMHKISOMQ-UHFFFAOYSA-N
MW2090.63 g/mol
LogP22.72
Rot. Bonds20

About 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine

3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine (PubChem CID 158237164) has the molecular formula C90H66F27N25O5 and a molecular weight of 2090.63 g/mol. Its IUPAC name is 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine.

Molecular Properties

Compound Name3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine
PubChem CID158237164
Molecular FormulaC90H66F27N25O5
Molecular Weight2090.63 g/mol
Exact Mass2089.52
IUPAC Name3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine
SMILESCC(C)Oc1ccc(-c2cn3c(C(C)(F)F)nnc3cn2)cc1.CC(F)(F)c1nnc2cnc(-c3ccc(C(F)(F)F)cc3F)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC(F)(F)F)c(F)c3)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC4CC(F)(F)C4)cc3)cn12.CC(F)(F)c1nnc2cnc(-c3cnc(OCC(F)(F)F)c(F)c3)cn12.FC(F)(F)Oc1ccc(-c2cn3c(C4CC4)nnc3cn2)cc1
InChIInChI=1S/C17H14F4N4O.C16H16F2N4O.C15H11F3N4O.C14H9F6N5O.C14H8F6N4O.C14H8F6N4/c1-16(18,19)15-24-23-14-8-22-13(9-25(14)15)10-2-4-11(5-3-10)26-12-6-17(20,21)7-12;1-10(2)23-12-6-4-11(5-7-12)13-9-22-14(8-19-13)20-21-15(22)16(3,17)18;16-15(17,18)23-11-5-3-9(4-6-11)12-8-22-13(7-19-12)20-21-14(22)10-1-2-10;1-13(16,17)12-24-23-10-4-21-9(5-25(10)12)7-2-8(15)11(22-3-7)26-6-14(18,19)20;1-13(16,17)12-23-22-11-5-21-9(6-24(11)12)7-2-3-10(8(15)4-7)25-14(18,19)20;1-13(16,17)12-23-22-11-5-21-10(6-24(11)12)8-3-2-7(4-9(8)15)14(18,19)20/h2-5,8-9,12H,6-7H2,1H3;4-10H,1-3H3;3-8,10H,1-2H2;2-5H,6H2,1H3;2-6H,1H3;2-6H,1H3
InChIKeyGFCHWJMHKISOMQ-UHFFFAOYSA-N
XLogP22.72
TPSA317.52 Ų
H-Bond Donors
H-Bond Acceptors30
Rotatable Bonds20
Heavy Atoms147
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002090.63
LogP ≤ 522.72
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1030

Analyze 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine with MolForge

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Related Compounds

6-[2-[(2-fluorophenoxy)methyl]-5-(6-methyl-2-pyridinyl)-1H-imidazol-4-yl]-2-[4-[[5-(6-methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methoxy]phenyl]-[1,2,4]triazolo[1,5-a]pyridine
CID 132035500
3-(Difluoromethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;ethane;3-(1-fluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[2-methyl-5-(trifluoromethoxy)phenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine
CID 142362304
6-[5-Fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine;6-(4-propan-2-yloxyphenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362320
3-(2,2-Difluoropropyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;ethane;3-(3-fluoropropyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-b]pyridazine
CID 142362325
3-(1,1-Difluoroethyl)-6-[4-(trifluoromethoxymethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;ethane;3-(2-fluoroethyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362358
3-(1-Fluorocyclopropyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;1-[4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]phenyl]cyclobutane-1-carbonitrile;3-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362378
Ethane;3-(1-fluoroethyl)-6-[5-fluoro-6-(1,1,1-trifluoropropan-2-yloxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-(3-fluoro-3-methylcyclobutyl)oxy-3-pyridinyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362380
6-[6-(3,3-Difluorocyclobutyl)oxy-5-fluoro-3-pyridinyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine;ethane;3-(1-fluoroethyl)-6-[5-fluoro-6-(1,1,1-trifluoropropan-2-yloxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362383
3-(4-Fluorophenoxy)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362399
3-(1,1-Difluoroethyl)-6-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;ethane;6-[4-(methoxymethyl)phenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362405
3-(1,1-Difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;ethane;3-(1-fluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362426
6-[4-(3,3-Difluorocyclobutyl)oxyphenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(3,3-difluorocyclobutyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine
CID 142362429

Frequently Asked Questions

What is the IUPAC name of 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine?
The IUPAC name of 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine (CID 158237164) is 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine.
What is the SMILES notation for 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine?
The canonical SMILES for 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine is CC(C)Oc1ccc(-c2cn3c(C(C)(F)F)nnc3cn2)cc1.CC(F)(F)c1nnc2cnc(-c3ccc(C(F)(F)F)cc3F)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC(F)(F)F)c(F)c3)cn12.CC(F)(F)c1nnc2cnc(-c3ccc(OC4CC(F)(F)C4)cc3)cn12.CC(F)(F)c1nnc2cnc(-c3cnc(OCC(F)(F)F)c(F)c3)cn12.FC(F)(F)Oc1ccc(-c2cn3c(C4CC4)nnc3cn2)cc1.
What is the InChIKey of 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine?
The InChIKey is GFCHWJMHKISOMQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H14F4N4O.C16H16F2N4O.C15H11F3N4O.C14H9F6N5O.C14H8F6N4O.C14H8F6N4/c1-16(18,19)15-24-23-14-8-22-13(9-25(14)15)10-2-4-11(5-3-10)26-12-6-17(20,21)7-12;1-10(2)23-12-6-4-11(5-7-12)13-9-22-14(8-19-13)20-21-15(22)16(3,17)18;16-15(17,18)23-11-5-3-9(4-6-11)12-8-22-13(7-19-12)20-21-14(22)10-1-2-10;1-13(16,17)12-24-23-10-4-21-9(5-25(10)12)7-2-8(15)11(22-3-7)26-6-14(18,19)20;1-13(16,17)12-23-22-11-5-21-9(6-24(11)12)7-2-3-10(8(15)4-7)25-14(18,19)20;1-13(16,17)12-23-22-11-5-21-10(6-24(11)12)8-3-2-7(4-9(8)15)14(18,19)20/h2-5,8-9,12H,6-7H2,1H3;4-10H,1-3H3;3-8,10H,1-2H2;2-5H,6H2,1H3;2-6H,1H3;2-6H,1H3.
What are the key properties of 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine?
3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine has a molecular weight of 2090.63 g/mol, XLogP of 22.72, 20 rotatable bonds, 0 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for 3-cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine is sourced from PubChem (CID 158237164), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).