N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide

C143H124N20O16S3 — CID 158256058

About N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide

N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide (PubChem CID 158256058) has the molecular formula C143H124N20O16S3 and a molecular weight of 2474.89 g/mol. Its IUPAC name is N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide.

Molecular Properties

• Compound Name: N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide
• PubChem CID: 158256058
• Molecular Formula: C143H124N20O16S3
• Molecular Weight: 2474.89 g/mol
• Exact Mass: 2472.87
• IUPAC Name: N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide
• SMILES: COc1c(C(=O)NCCSC)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)NCCc2cccs2)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)NCCc2nccs2)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)N[C@@H](C)C(N)=O)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)N[C@@H]2CCOC2=O)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)N[C@H](CO)c2ccccc2)ccc2n[nH]c(-c3ccc4ccccc4c3)c12
• InChI: InChI=1S/C27H23N3O3.C25H21N3O2S.C24H20N4O2S.C23H19N3O4.C22H20N4O3.C22H21N3O2S/c1-33-26-21(27(32)28-23(16-31)18-8-3-2-4-9-18)13-14-22-24(26)25(30-29-22)20-12-11-17-7-5-6-10-19(17)15-20;1-30-24-20(25(29)26-13-12-19-7-4-14-31-19)10-11-21-22(24)23(28-27-21)18-9-8-16-5-2-3-6-17(16)15-18;1-30-23-18(24(29)26-11-10-20-25-12-13-31-20)8-9-19-21(23)22(28-27-19)17-7-6-15-4-2-3-5-16(15)14-17;1-29-21-16(22(27)24-18-10-11-30-23(18)28)8-9-17-19(21)20(26-25-17)15-7-6-13-4-2-3-5-14(13)12-15;1-12(21(23)27)24-22(28)16-9-10-17-18(20(16)29-2)19(26-25-17)15-8-7-13-5-3-4-6-14(13)11-15;1-27-21-17(22(26)23-11-12-28-2)9-10-18-19(21)20(25-24-18)16-8-7-14-5-3-4-6-15(14)13-16/h2-15,23,31H,16H2,1H3,(H,28,32)(H,29,30);2-11,14-15H,12-13H2,1H3,(H,26,29)(H,27,28);2-9,12-14H,10-11H2,1H3,(H,26,29)(H,27,28);2-9,12,18H,10-11H2,1H3,(H,24,27)(H,25,26);3-12H,1-2H3,(H2,23,27)(H,24,28)(H,25,26);3-10,13H,11-12H2,1-2H3,(H,23,26)(H,24,25)/t23-;;;18-;12-;/m1..10./s1
• InChIKey: GHHKYBLRHGHFCY-PIQBKORASA-N
• XLogP: 26.02
• TPSA: 504.57 Ų
• H-Bond Donors: 14
• H-Bond Acceptors: 26
• Rotatable Bonds: 33
• Heavy Atoms: 182
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2474.89
LogP ≤ 5	26.02
H-Bond Donors ≤ 5	14
H-Bond Acceptors ≤ 10	26

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide?

The IUPAC name of N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide (CID 158256058) is N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide.

What is the SMILES notation for N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide?

The canonical SMILES for N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide is COc1c(C(=O)NCCSC)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)NCCc2cccs2)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)NCCc2nccs2)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)N[C@@H](C)C(N)=O)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)N[C@@H]2CCOC2=O)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.COc1c(C(=O)N[C@H](CO)c2ccccc2)ccc2n[nH]c(-c3ccc4ccccc4c3)c12.

What is the InChIKey of N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide?

The InChIKey is GHHKYBLRHGHFCY-PIQBKORASA-N. The full InChI is InChI=1S/C27H23N3O3.C25H21N3O2S.C24H20N4O2S.C23H19N3O4.C22H20N4O3.C22H21N3O2S/c1-33-26-21(27(32)28-23(16-31)18-8-3-2-4-9-18)13-14-22-24(26)25(30-29-22)20-12-11-17-7-5-6-10-19(17)15-20;1-30-24-20(25(29)26-13-12-19-7-4-14-31-19)10-11-21-22(24)23(28-27-21)18-9-8-16-5-2-3-6-17(16)15-18;1-30-23-18(24(29)26-11-10-20-25-12-13-31-20)8-9-19-21(23)22(28-27-19)17-7-6-15-4-2-3-5-16(15)14-17;1-29-21-16(22(27)24-18-10-11-30-23(18)28)8-9-17-19(21)20(26-25-17)15-7-6-13-4-2-3-5-14(13)12-15;1-12(21(23)27)24-22(28)16-9-10-17-18(20(16)29-2)19(26-25-17)15-8-7-13-5-3-4-6-14(13)11-15;1-27-21-17(22(26)23-11-12-28-2)9-10-18-19(21)20(25-24-18)16-8-7-14-5-3-4-6-15(14)13-16/h2-15,23,31H,16H2,1H3,(H,28,32)(H,29,30);2-11,14-15H,12-13H2,1H3,(H,26,29)(H,27,28);2-9,12-14H,10-11H2,1H3,(H,26,29)(H,27,28);2-9,12,18H,10-11H2,1H3,(H,24,27)(H,25,26);3-12H,1-2H3,(H2,23,27)(H,24,28)(H,25,26);3-10,13H,11-12H2,1-2H3,(H,23,26)(H,24,25)/t23-;;;18-;12-;/m1..10./s1.

What are the key properties of N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide?

N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide has a molecular weight of 2474.89 g/mol, XLogP of 26.02, 33 rotatable bonds, 14 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(2S)-1-amino-1-oxopropan-2-yl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;N-[(1S)-2-hydroxy-1-phenylethyl]-4-methoxy-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-N-(2-methylsulfanylethyl)-3-naphthalen-2-yl-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[(3R)-2-oxooxolan-3-yl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-[2-(1,3-thiazol-2-yl)ethyl]-2H-indazole-5-carboxamide;4-methoxy-3-naphthalen-2-yl-N-(2-thiophen-2-ylethyl)-2H-indazole-5-carboxamide is sourced from PubChem (CID 158256058), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).